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Chloramphenicol

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Identification
Molecular formula
C11H12Cl2N2O5
CAS number
56-75-7
IUPAC name
1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene
State
State

Chloramphenicol is typically found as a solid at room temperature.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
419.50
Boiling point (Kelvin)
692.65
General information
Molecular weight
323.13g/mol
Molar mass
323.1310g/mol
Density
1.2430g/cm3
Appearence

Chloramphenicol is a white to grayish-white crystalline powder. It is generally tasteless and has no discernible odor. The compound is often encountered as a fine powder.

Comment on solubility

Solubility of 1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene

The solubility of the compound 1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene in various solvents is influenced by its molecular structure and polarity.

Key Points:

  • Polarity: The presence of chlorine and nitro groups in the compound contributes to a higher polarity, which typically enhances solubility in polar solvents.
  • Solubility in Water: The compound is expected to have low solubility in water due to its larger hydrophobic hydrocarbon portions, making it less amenable to interaction with polar solvent molecules.
  • Organic Solvents: It is more likely to dissolve in organic solvents like ethanol, acetone, or chloroform, where its non-polar regions can effectively interact.
  • Temperature Effects: Solubility may increase with temperature, as increased kinetic energy can help disrupt intermolecular forces.

In summary, while 1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene may exhibit limited solubility in polar solvents such as water, its compatibility with various organic solvents highlights the significance of molecular structure on solubility behavior. Such compounds warrant careful consideration in applications requiring specific solubility characteristics.

Interesting facts

Interesting Facts about 1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene

This compound, known for its unique structure, belongs to a class of organic molecules that incorporate both chlorine and nitro groups, making it of particular interest in medicinal chemistry and material science. Here are some intriguing points about it:

  • Structure and Substituents: The compound features a complex arrangement of substituents including a 4-chlorophenyl group and a nitro-butyl chain. This diversity of functional groups can significantly influence its chemical reactivity and biological activity.
  • Synthetic Applications: Compounds such as 1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene are often used as intermediates in the synthesis of pharmaceuticals. Their versatile structure allows for various modifications to enhance specific properties.
  • Biological Relevance: The presence of chlorine and nitro groups suggests potential antimicrobial and anticancer properties, which are often investigated in drugs designed for therapeutic applications.
  • Research Interest: Scientists continue to explore the functional roles of similar compounds in various fields including organic electronics and agrochemicals, where their stability and reactivity can be harnessed.

As the demand for novel pharmaceuticals and materials increases, compounds like 1-chloro-4-[1-(4-chlorophenyl)-2-nitro-butyl]benzene are likely to remain a focal point of study due to their multifaceted characteristics and potential applications. Understanding the intricacies of such compounds not only enhances our knowledge of organic chemistry but also paves the way for innovations in drug development and materials engineering.

Synonyms
BULAN
117-26-0
Caswell No. 092A
1,1-Bis(4-chlorophenyl)-2-nitrobutane
CS 674A
1,1'-(2-Nitrobutylidene)bis(4-chlorobenzene)
1-Chloro-4-[1-(4-chlorophenyl)-2-nitrobutyl]benzene
ENT 18,065
1,1-Bis(p-chlorophenyl)-2-nitrobutane
2-Nitro-1,1-bis(p-chlorophenyl)butane
HSDB 1420
Butane, 1,1-bis(p-chlorophenyl)-2-nitro-
UNII-F22DJI2649
BRN 2509596
BULAN [HSDB]
BULAN [MI]
Benzene, 1,1'-(2-nitrobutylidene)bis(4-chloro-
DTXSID1041687
F22DJI2649
4-05-00-01944 (Beilstein Handbook Reference)
Benzene, 1,1'-(2-nitrobutylidene)bis[4-chloro-
1,1'-(2-Nitrobutylidene)bis[4-chlorobenzene]
SCHEMBL115818
DTXCID9021687
1,1Bis(pchlorophenyl)2nitrobutane
2Nitro1,1bis(pchlorophenyl)butane
1,1Bis(4chlorophenyl)2nitrobutane
Butane, 1,1bis(pchlorophenyl)2nitro
USEPA/OPP Pesticide Code: 056602
1,1'(2Nitrobutylidene)bis(4chlorobenzene)
Benzene, 1,1'(2nitrobutylidene)bis(4chloro
NS00125464
Q21546939
1-Chloro-4-[1-(4-chlorophenyl)-2-nitrobutyl]benzene #