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4-[(4-Fluorophenyl)thio]benzyl chloride

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Identification
Molecular formula
C13H10ClFS
CAS number
774-50-9
IUPAC name
1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene
State
State

This compound is a solid at room temperature, characterized by its crystalline structure.

Melting point (Celsius)
59.00
Melting point (Kelvin)
332.20
Boiling point (Celsius)
355.40
Boiling point (Kelvin)
628.50
General information
Molecular weight
250.72g/mol
Molar mass
250.7220g/mol
Density
1.2990g/cm3
Appearence

4-[(4-Fluorophenyl)sulfanylmethyl]benzene appears as a white to off-white crystalline solid. Its crystalline structure contributes to its solid state at room temperature.

Comment on solubility

Solubility of 1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene

1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene exhibits interesting solubility characteristics that are influenced by its structural components. Understanding its solubility is essential for various applications, particularly in pharmaceuticals and organic synthesis.

Factors Affecting Solubility:

  • Polarity: The presence of the chloro group increases its dipole moment, influencing solubility in polar solvents.
  • Molecular Interactions: The sulfanylmethyl group enhances interactions with other organic compounds, which can improve solubility in certain organic solvents.
  • Hydrophobic Regions: The aromatic rings in the structure contribute to hydrophobic characteristics, which may limit solubility in polar solvents.

In general, 1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene is expected to have:

  • Moderate Solubility: Likely to be more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone.
  • Poor Solubility in Water: Given its structure, it is likely to have limited solubility in aqueous environments.

Therefore, when working with this compound, one must consider the choice of solvent for optimal dissolution and reactivity.

Interesting facts

Interesting Facts about 1-Chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene

The compound 1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene, often abbreviated as part of complex organic syntheses, exhibits several intriguing characteristics that highlight its significance in the field of chemistry.

Chemical Structure and Properties

  • Chlorine Influence: The presence of a chlorine atom in its structure contributes to its reactivity, making it a valuable intermediate in organic synthesis.
  • Sulfanyl Group: The sulfanylmethyl group enhances its nucleophilic properties, which can be exploited in various chemical reactions.
  • Fluorine Effects: The fluorophenyl component often affects the electronic properties of the molecule, providing unique challenges and opportunities in reactivity and interaction with biological systems.

Applications in Industry

This compound plays a critical role in the synthesis of:

  • Pharmaceuticals: It may serve as a precursor in the synthesis of drug molecules due to the unique interactions offered by its functional groups.
  • Pesticides: Compounds with similar structures are often investigated for agricultural applications, aimed at enhancing crop protection.
  • Material Science: Its chemical characteristics can be utilized in the development of advanced materials and polymers.

Research Highlights

Investigating this compound can lead to insights into:

  • Mechanistic Pathways: Understanding how 1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene interacts in various chemical reactions.
  • Biological Activity: Studies may reveal how it affects biological systems, influencing drug design and discovery.

This compound exemplifies the intersection of structure and function in organic chemistry, showcasing how slight variations in molecular composition can drastically influence its behavior in chemical reactions and its applicability in various scientific fields.

Synonyms
FLUORBENSIDE
405-30-1
Fluoroparacide
Fluorparacide
Fluorsulphacide
Fluorosulphacide
Fluorosulfacide
1-chloro-4-[(4-fluorophenyl)sulfanylmethyl]benzene
Fluorbenside [ISO]
Caswell No. 183B
p-Chlorobenzyl p-fluorophenyl sulphide
p-Chlorobenzyl p-fluorophenyl sulfide
Sulfide, p-chlorobenzyl p-fluorophenyl
4-Chlorobenzyl 4'-fluorophenyl sulphide
HSDB 1539
HRS 942
4-Chlorobenzyl 4-fluorphenyl sulphide
EPA Pesticide Chemical Code 283300
4-Chlorobenzyl 4'-fluorophenyl sulfide
RD 2454
BRN 3291675
1-Chloro-4-(((4-fluorophenyl)thio)methyl)benzene
UNII-Q449322QX1
Benzene, 1-chloro-4-(((4-fluorophenyl)thio)methyl)-
FLUORBENSIDE [HSDB]
Q449322QX1
DTXSID6041979
4-CHLOROBENZYL 4-FLUOROPHENYL SULFIDE
SCHEMBL166370
DTXCID4021979
pChlorobenzyl pfluorophenyl sulfide
4Chlorobenzyl 4fluorphenyl sulphide
pChlorobenzyl pfluorophenyl sulphide
Sulfide, pchlorobenzyl pfluorophenyl
4Chlorobenzyl 4'fluorophenyl sulfide
4Chlorobenzyl 4'fluorophenyl sulphide
1Chloro4(((4fluorophenyl)thio)methyl)benzene
Benzene, 1chloro4(((4fluorophenyl)thio)methyl)
Q27286968