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4-Chlorobenzyl chloride

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Identification
Molecular formula
C7H6Cl2S
CAS number
1192-37-6
IUPAC name
1-chloro-4-(chloromethylsulfanyl)benzene
State
State

4-Chlorobenzyl chloride is a liquid at room temperature.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
234.00
Boiling point (Kelvin)
507.15
General information
Molecular weight
191.09g/mol
Molar mass
191.0850g/mol
Density
1.3200g/cm3
Appearence

At room temperature, 4-Chlorobenzyl chloride exists as a colorless or pale yellow liquid. It may appear slightly oily and exhibits a sharp odor typical of chlorinated aromatic compounds. It should be handled with caution, as chlorinated compounds can be hazardous.

Comment on solubility

Solubility of 1-chloro-4-(chloromethylsulfanyl)benzene

1-chloro-4-(chloromethylsulfanyl)benzene, with its complex structure, exhibits intriguing solubility characteristics. As a member of the chlorinated aromatic compounds, its solubility profile is influenced by several key factors:

  • Polarity: The presence of chlorine atoms contributes to the overall polarity of the molecule, potentially enhancing solubility in polar solvents.
  • Solvent Compatibility: This compound tends to be more soluble in organic solvents such as chloroform or ethyl acetate than in water.
  • Temperature Effect: Increasing temperature typically aids in the solubility of many organic compounds, and this one may behave similarly.

It’s noteworthy that, despite its chlorinated nature, it may exhibit limited solubility in water due to hydrophobic segments that resist interaction with the polar solvent. In summary, while 1-chloro-4-(chloromethylsulfanyl)benzene displays a propensity to dissolve in certain organic mediums, its solubility in aqueous environments remains quite restricted.

Interesting facts

Interesting Facts about 1-Chloro-4-(chloromethylsulfanyl)benzene

1-Chloro-4-(chloromethylsulfanyl)benzene is a fascinating compound that belongs to the class of aromatic compounds known as halogenated benzenes. This compound has a variety of applications in the field of organic synthesis and materials chemistry. Here are some intriguing details about it:

  • Functional Groups: The molecule features both a chloro group and a chloromethylsulfanyl group, making it a valuable precursor in various synthetic pathways.
  • Versatile Reagents: The chloromethylsulfanyl group can act as a nucleophile or electrophile, allowing for multiple reaction pathways. This versatility makes it useful in designing complex chemical structures.
  • Applications in Industry: In the pharmaceutical industry, derivatives of chlorinated benzenes are often used as starting materials for the synthesis of drugs and agrochemicals.
  • Toxicology Considerations: Like many halogenated compounds, 1-chloro-4-(chloromethylsulfanyl)benzene may pose environmental and health risks, which underscores the importance of handling and disposal considerations in laboratory settings.
  • In the Laboratory: This compound can be used in the synthesis of sulfonamide antibiotics, which have historically played a crucial role in the treatment of bacterial infections.

In summary, 1-chloro-4-(chloromethylsulfanyl)benzene is not just another chemical; it's a gateway to understanding complex organic syntheses and their applications in medicine and industry. As with many compounds, proper safety measures are essential when working with it, highlighting the importance of responsible chemistry practice.

Synonyms
7205-90-5
Chloromethyl 4-chlorophenyl sulphide
p-Chloro-S-chloromethylbenzenethiol
Thiophenol, p-chloro-S-chloromethyl
p-Chlorfenyl-chlormethylsulfid
1-Chloro-4-(chloromethylthio)benzene
p-Chlorfenylmerkaptomethylchlorid
EINECS 230-578-1
p-Chlorfenyl-chlormethylsulfid [Czech]
BRN 2043507
p-Chlorfenylmerkaptomethylchlorid [Czech]
Benzene, 1-chloro-4-((chloromethyl)thio)-
Benzene, 1-chloro-4-[(chloromethyl)thio]-
Thiophenol, p-chloro-S-chloromethyl-
4-06-00-01593 (Beilstein Handbook Reference)
1-Chloro-4-((chloromethyl)thio)benzene
1-Chloro-4-[(chloromethyl)thio]benzene
230-578-1
inchi=1/c7h6cl2s/c8-5-10-7-3-1-6(9)2-4-7/h1-4h,5h
Chloromethyl 4-chlorophenyl sulfide
1-chloro-4-(chloromethylsulfanyl)benzene
Sulfide, chloromethyl p-chlorophenyl
1-chloro-4-chloromethylthiobenzene
SCHEMBL907105
DTXSID0064593
Chloromethyl p-chlorophenyl sulfide
p-Chlorophenyl chloromethyl sulfide
(p-Chlorophenylthio)methyl chloride
(4-Chlorophenyl)thiomethyl chloride
4-Chloro-1-(chloromethylthio)benzene
AKOS015889055
Chloromethyl 4-chlorophenyl sulfide,98%
Chloromethyl 4-chlorophenyl sulfide, 97%
1-Chloro-4-[(chloromethyl)sulfanyl]benzene
C3670
NS00037322
1-Chloro-4-[(chloromethyl)sulfanyl]benzene #