Skip to main content

1-Chloro-4-fluorobenzene

ADVERTISEMENT
Identification
Molecular formula
C6H4ClF
CAS number
352-33-4
IUPAC name
1-chloro-4-fluoro-benzene
State
State
This compound is in a liquid state at room temperature.
Melting point (Celsius)
-1.00
Melting point (Kelvin)
272.15
Boiling point (Celsius)
130.50
Boiling point (Kelvin)
403.65
General information
Molecular weight
128.56g/mol
Molar mass
128.5560g/mol
Density
1.2471g/cm3
Appearence

1-Chloro-4-fluorobenzene is a colorless liquid with a sharp, aromatic odor characteristic of other halogenated benzenes.

Comment on solubility

Solubility of 1-chloro-4-fluoro-benzene

1-chloro-4-fluoro-benzene, with the chemical formula C6H4ClF, exhibits intriguing solubility characteristics, primarily influenced by its molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of both the chlorine and fluorine atoms introduces significant polar character to the molecule, affecting its interactions with solvents.
  • Solvent Compatibility: 1-chloro-4-fluoro-benzene is generally more soluble in non-polar solvents like hexane or toluene, demonstrating its affinity for hydrophobic environments.
  • Poor Water Solubility: This compound exhibits low solubility in water, which is typical for many halogenated aromatic compounds due to their hydrophobic nature.
  • Temperature Effects: Solubility can also vary with temperature, potentially increasing in organic solvents as temperature rises.

In summary, while 1-chloro-4-fluoro-benzene may not dissolve readily in polar solvents like water, it is compatible with a variety of non-polar and weakly polar solvents, making it versatile for uses in organic synthesis and other chemical applications. Its solubility characteristics reflect its unique molecular interactions driven by both dipole moments and the aromatic system's stability.

Interesting facts

Interesting Facts about 1-Chloro-4-fluoro-benzene

1-Chloro-4-fluoro-benzene is a fascinating aromatic compound that belongs to the class of halogenated benzenes. Its unique structure and functional groups contribute to various interesting properties and applications. Here are some noteworthy highlights:

  • Halogenated Hydrocarbons: This compound contains both chlorine and fluorine atoms, making it a part of the halogenated hydrocarbon family, which is essential in various industrial processes.
  • Applications in Synthesis: 1-Chloro-4-fluoro-benzene is often utilized as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, due to the reactivity of its halogen atoms.
  • Electrophilic Substitution Reactions: The presence of both the chloro and fluoro substituents enables this compound to undergo electrophilic substitution reactions, a vital reaction pathway in organic chemistry.
  • Environmental Considerations: Halogenated compounds like this are studied for their environmental impact, particularly their role in atmospheric chemistry and potential effects on ozone depletion.
  • Research Relevance: Due to its chemical characteristics, 1-chloro-4-fluoro-benzene is frequently found in research focused on developing new materials, including polymer chemistry and liquid crystal applications.

As stated by many chemists, “The beauty of organic chemistry lies in understanding the intricacies of compound interactions.” 1-chloro-4-fluoro-benzene exemplifies this beauty, demonstrating how simple structural variations can significantly influence the properties and behaviors of compounds.

In summary, this compound serves as a vital building block in organic synthesis and environmental research, showcasing the intricate connections within chemistry.

Synonyms
1-Chloro-4-fluorobenzene
352-33-0
p-Chlorofluorobenzene
p-Fluorochlorobenzene
Benzene, 1-chloro-4-fluoro-
4-Chlorofluorobenzene
4-Fluorochlorobenzene
1-Fluoro-4-chlorobenzene
1-Chloro-4-fluoro-benzene
55256-17-2
1,4-Fluorochlorobenzene
EINECS 206-521-1
NSC 10272
DTXSID2059853
1-Chloro-4-fluorobenzene, 98%
NSC-10272
pChlorofluorobenzene
pFluorochlorobenzene
NSC10272
1Fluoro4chlorobenzene
p-chloro-fluorobenzene
4-fluorophenyl chloride
Benzene, 1chloro4fluoro
1-chloro-4-fluorbenzene
1-Chlor-4-fluor-benzol
4MH2SJ5JJR
SCHEMBL35226
1-chloranyl-4-fluoranyl-benzene
DTXCID1038959
MFCD00000603
AKOS006222741
AC-10630
PS-11967
A6188
NS00041648
EN300-97493
D89284
A822665
206-521-1