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para-Anisyl chloride

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Identification
Molecular formula
C7H7ClO
CAS number
104-94-9
IUPAC name
1-chloro-4-methoxy-benzene
State
State

At room temperature, para-Anisyl chloride exists as a liquid. It should be handled with care due to its volatile nature and potential to emit fumes.

Melting point (Celsius)
13.00
Melting point (Kelvin)
286.15
Boiling point (Celsius)
218.00
Boiling point (Kelvin)
491.15
General information
Molecular weight
142.58g/mol
Molar mass
142.5840g/mol
Density
1.1050g/cm3
Appearence

Para-Anisyl chloride is typically a colorless to pale-yellow liquid with a characteristic aromatic odor. It is clear and can become slightly yellow upon exposure to light or air over time.

Comment on solubility

Solubility of 1-Chloro-4-methoxy-benzene

1-Chloro-4-methoxy-benzene, also known as para-chloroanisole, exhibits notable solubility characteristics that can be summarized as follows:

  • General Solubility: This compound is considered to be sparingly soluble in water due to its hydrophobic aromatic structure, which hinders interaction with polar water molecules.
  • Solvent Preferences: It demonstrates good solubility in organic solvents, particularly:
    • Alcohols (e.g., ethanol)
    • Aromatic hydrocarbons (e.g., toluene)
    • Chlorinated solvents (e.g., dichloromethane)
  • Influence of Functional Groups: The presence of both the −Cl and −OCH3 groups adds complexity to its solubility profile, affecting polarity and interaction potential.

In summary, while 1-chloro-4-methoxy-benzene is not soluble in water, it finds a compatible environment in various organic solvents that enhance its solubility and enable practical applications in laboratory settings.

Interesting facts

Interesting Facts about 1-Chloro-4-methoxy-benzene

1-Chloro-4-methoxy-benzene, commonly referred to as p-chloroanisole, is an organic compound that holds significant interest within the fields of chemistry and material science. Here are some engaging facts about this compound:

  • Versatile Applications: This compound is predominantly used as a building block in organic synthesis, particularly in the production of various pharmaceuticals, agrochemicals, and other industrial chemicals.
  • Unique Aroma: Many chlorinated aromatic compounds are known for their distinct scents. In the case of p-chloroanisole, it is often noted for its sweet and pleasant aroma, making it relevant in the fragrance industry.
  • Biochemical Relevance: Research indicates that derivatives of p-chloroanisole exhibit antimicrobial properties. This raises potential implications for its use in developing new disinfectants or preservatives.
  • Environmental Considerations: As with many chlorinated compounds, 1-chloro-4-methoxy-benzene's environmental impact is a topic of interest. Its degradation and the byproducts formed during its breakdown are essential for understanding its ecological effects.
  • Reactivity and Structure: The presence of both the chlorine and the methoxy group on the benzene ring induces a unique reactivity profile. This makes this compound a fascinating subject for studying substitution reactions in aromatic chemistry.

In summary, 1-chloro-4-methoxy-benzene represents a blend of industrial utility, chemical curiosity, and environmental significance. Its diverse applications and the structural influences on its reaction behavior make it a compound worthy of exploration.

Synonyms
4-Chloroanisole
1-Chloro-4-methoxybenzene
Benzene, 1-chloro-4-methoxy-
P-CHLOROANISOLE
p-Chlorophenyl methyl ether
Anisole, p-chloro-
Anisyl chloride
p-Chloromethoxybenzene
4-Chlorophenol methyl ether
1-methoxy-4-chlorobenzene
4-Monochloroanisole
p-methoxychlorobenzene
4-METHOXYCHLOROBENZENE
p-methoxyphenyl chloride
4-methoxyphenyl chloride
para-Chloroanisole
NSC 4129
UNII-0F18BLY08Q
0F18BLY08Q
NSC-4129
EINECS 210-772-2
AI3-07211
DTXSID1060764
4-CHLOROPHENYL METHYL ETHER
pChloroanisole
Anisole, pchloro
4Monochloroanisole
pChloromethoxybenzene
1Chloro4methoxybenzene
Benzene, 1chloro4methoxy
pChlorophenyl methyl ether
Anisole, pchloro (8CI)
4Chlorophenol methyl ether
Anisole, p-chloro-(8CI)
DTXCID7043295
210-772-2
inchi=1/c7h7clo/c1-9-7-4-2-6(8)3-5-7/h2-5h,1h
yrgayagbvixnaq-uhfffaoysa-n
623-12-1
1-chloro-4-methoxy-benzene
4-Chloroanisole--d4
MFCD00000616
1219804-86-0
4-chloroanisol
4-chloro-anisole
p-anisolyl chloride
4-Chloroanisole, 99%
SCHEMBL154527
SCHEMBL11036846
SCHEMBL12015226
NSC4129
STL301917
AKOS008948222
CS-W011015
FC64630
AC-14974
AS-12682
SY005701
DB-054127
NS00035003
EN300-65450
Q27236691
F0001-1669