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(3-Fluorophenyl)methyl chloride

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Identification
Molecular formula
C7H6ClF
CAS number
456-42-8
IUPAC name
1-(chloromethyl)-3-fluoro-benzene
State
State

At room temperature, (3-Fluorophenyl)methyl chloride is in a liquid state.

Melting point (Celsius)
-15.00
Melting point (Kelvin)
258.15
Boiling point (Celsius)
188.20
Boiling point (Kelvin)
461.35
General information
Molecular weight
144.57g/mol
Molar mass
144.5700g/mol
Density
1.1980g/cm3
Appearence

(3-Fluorophenyl)methyl chloride is typically a colorless liquid. It may have a slightly yellowish tint and is often noted for its sharp smell.

Comment on solubility

Solubility of 1-(chloromethyl)-3-fluoro-benzene

Understanding the solubility of 1-(chloromethyl)-3-fluoro-benzene (C8H8ClF) within various solvents can provide essential insights into its behavior in different environments. Here are some key points regarding its solubility:

  • Polar Solvents: This compound is likely to have *limited solubility* in polar solvents such as water, due to its hydrophobic aromatic structure. The presence of a chlorine atom and a fluorine atom influences its interaction with water molecules.
  • Non-polar Solvents: In contrast, 1-(chloromethyl)-3-fluoro-benzene is expected to be more soluble in non-polar solvents, like hexane or benzene, owing to its overall non-polar characteristics stemming from the aromatic ring.
  • Effects of Temperature: The solubility can also *vary significantly* with temperature; typically, increasing temperature will increase the solubility in organic solvents.
  • Practical Importance: Understanding its solubility is critical for applications in chemical synthesis, extraction processes, and industrial applications where its solubility profile can affect reactivity and product yield.

In summary, while 1-(chloromethyl)-3-fluoro-benzene exhibits limited solubility in polar solvents, it finds greater compatibility with non-polar solvents. Thus, when working with this compound, it is crucial to consider the solvent choice in order to optimize its usage in chemical applications.

Interesting facts

Interesting Facts About 1-(Chloromethyl)-3-fluoro-benzene

1-(Chloromethyl)-3-fluoro-benzene, a member of the aromatic halide family, exhibits unique characteristics that make it a subject of interest in both synthetic chemistry and industrial applications. Below are some intriguing points about this fascinating compound:

  • Reactivity: The presence of both a fluorine and a chloromethyl group significantly alters the reactivity of this compound. The fluorine atom can engage in various chemical transformations, making it a useful building block for more complex molecules.
  • Applications in Synthesis: This compound can be utilized in the synthesis of pharmaceuticals and agrochemicals. The halogen atoms make it an excellent candidate for nucleophilic substitution reactions, paving the way for the creation of more complex organic structures.
  • Environmental Considerations: As with many halogenated compounds, it's important to consider the environmental impact and potential toxicity of 1-(chloromethyl)-3-fluoro-benzene. Proper handling and disposal methods should always be followed in laboratory and industrial settings.
  • Research Interests: Ongoing research into this compound focuses on its potential in medicinal chemistry, particularly for developing new therapies and understanding its behavior in various biological systems.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” This sentiment rings true for compounds like 1-(chloromethyl)-3-fluoro-benzene, which may lead to new discoveries and advancements in chemical research.

In conclusion, the unique attributes of 1-(chloromethyl)-3-fluoro-benzene make it a vital compound in the world of chemistry, prompting further investigation and exploration. Its versatility allows scientists to push the boundaries of chemical synthesis and contribute to innovative applications across multiple fields.

Synonyms
3-Fluorobenzyl chloride
456-42-8
1-(Chloromethyl)-3-fluorobenzene
M-FLUOROBENZYL CHLORIDE
Benzene, 1-(chloromethyl)-3-fluoro-
3-Fluorobenzylchloride
1-Chloromethyl-3-fluoro-benzene
Toluene, .alpha.-chloro-m-fluoro-
EINECS 207-264-8
NSC 60720
3-Fluorophenylmethyl chloride
.alpha.-Chloro-m-fluorotoluene
.alpha.-Chloro-3-fluorotoluene
DTXSID4060026
NSC-60720
alpha-Chloro-3-fluorotoluene
alpha-Chloro-m-fluorotoluene
MFCD00000904
3-flurobenzylchloride
m-fluorobenzylchloride
mFluorobenzyl chloride
3-flourobenzyl chloride
alphaChloromfluorotoluene
alphaChloro3fluorotoluene
m-fluoro-benzyl chloride
3-fluoro-benzyl chloride
DXT56E2KBP
Toluene, alphachloromfluoro
SCHEMBL70652
1(Chloromethyl)3fluorobenzene
3-Fluorobenzyl chloride, 96%
DTXCID8040438
Benzene, 1(chloromethyl)3fluoro
Toluene, alpha-chloro-m-fluoro-
Toluene, alphachloromfluoro (8CI)
CS-D0813
NSC60720
STL195659
AKOS000120643
AC-26193
DB-024085
F0210
NS00126547
EN300-18208
A22404
F2190-0252
m-Fluorobenzyl chloride; alpha-Chloro-m-fluorotoluene; 1-(Chloromethyl)-3-fluoro-benzene
-(chloromethyl)-3-fluoro-benzen;3-Fluorophenylmethyl chloride;Toluene, alpha-chloro-m-fluoro-