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1-(Chloromethyl)pyrrole-2,5-dione

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Identification
Molecular formula
C5H4ClNO2
CAS number
993-70-0
IUPAC name
1-(chloromethyl)pyrrole-2,5-dione
State
State

At room temperature, 1-(Chloromethyl)pyrrole-2,5-dione is generally found in a solid state. It is often handled as a crystalline material and is usually stable under standard conditions of temperature and pressure.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.00
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.00
General information
Molecular weight
145.55g/mol
Molar mass
145.5450g/mol
Density
1.3700g/cm3
Appearence

1-(Chloromethyl)pyrrole-2,5-dione appears as a white to light brown crystalline solid. It can sometimes also appear as a powder depending on the form it is obtained. The solid form often features a somewhat crystalline structure.

Comment on solubility

Solubility of 1-(chloromethyl)pyrrole-2,5-dione

The solubility of 1-(chloromethyl)pyrrole-2,5-dione can be characterized by various factors that influence its interaction with solvents. Understanding these factors is essential for applications in organic synthesis and materials science.

Key Points on Solubility

  • Polarity: This compound features polar functional groups which may enhance its solubility in polar solvents such as water and alcohols.
  • Hydrophobic regions: The presence of chloromethyl groups can introduce hydrophobic characteristics, potentially leading to lower solubility in very polar solvents.
  • Solvent compatibility: 1-(chloromethyl)pyrrole-2,5-dione may demonstrate varying solubility across different organic solvents:
    • Highly soluble: Ethanol, Methanol
    • Moderate solubility: Acetone, Chloroform
    • Poor solubility: Hexane, Toluene

As a result, researchers often recommend testing solubility in different solvents to determine the most effective medium for their specific applications. In summary, the solubility of 1-(chloromethyl)pyrrole-2,5-dione is a complex interplay of its structural properties and the solvent used, making it a compound of interest for solubility studies.

Interesting facts

Interesting Facts about 1-(Chloromethyl)pyrrole-2,5-dione

1-(Chloromethyl)pyrrole-2,5-dione is an intriguing compound that has gained attention in the field of organic chemistry. Here are some captivating insights about this compound:

  • Identity and Structure: This compound features a pyrrole ring, which is a five-membered aromatic ring containing nitrogen. The addition of a chloromethyl group enhances its reactivity, positioning it as a versatile intermediate in organic syntheses.
  • Applications: It is particularly noted for its utility in the synthesis of pharmaceuticals and agrochemicals. Its unique structure allows it to serve as a building block for more complex molecules.
  • Biological Activity: Some derivatives of pyrrole-2,5-dione exhibit interesting biological properties, including antimicrobial and antiviral activities. This makes the study of 1-(chloromethyl)pyrrole-2,5-dione relevant to medicinal chemistry.
  • Reactivity: Due to the presence of both a chlorine atom and a double-bonded oxygen in its structure, this compound can participate in various chemical reactions, including nucleophilic substitutions and cycloadditions.
  • Research Significance: Ongoing research is being conducted to understand the mechanisms through which this compound interacts at the molecular level, paving the way for advances in chemical synthesis and drug development.

As scientists delve deeper into the properties and potential applications of 1-(chloromethyl)pyrrole-2,5-dione, it stands to play a significant role in the synthesis of novel compounds that could lead to breakthroughs in various fields of chemistry.

Synonyms
7685-96-3
MALEIMIDE, N-CHLOROMETHYL-
N-Chloromethylmaleimide
1H-Pyrrole-2,5-dione, 1-(chloromethyl)-
BRN 0115740
AI3-61980
DTXSID70227661
4-21-00-04637 (Beilstein Handbook Reference)
DTXCID20150152
1-(chloromethyl)pyrrole-2,5-dione
SCHEMBL4813241
AKOS006385709
1-(chloromethyl)-2,5-dihydro-1H-pyrrole-2,5-dione