Skip to main content

1-Chloropiperidine

ADVERTISEMENT
Identification
Molecular formula
C5H10ClN
CAS number
123-03-5
IUPAC name
1-chloropiperidine
State
State

1-Chloropiperidine is typically a liquid at room temperature.

Melting point (Celsius)
-44.30
Melting point (Kelvin)
228.85
Boiling point (Celsius)
150.01
Boiling point (Kelvin)
423.16
General information
Molecular weight
105.58g/mol
Molar mass
105.5800g/mol
Density
0.9838g/cm3
Appearence

1-Chloropiperidine appears as a colorless to pale yellow liquid. This compound is typically clear and is known to have an unpleasant or distinctive odor. It can be handled as a liquid under normal laboratory conditions.

Comment on solubility

Solubility of 1-Chloropiperidine

1-Chloropiperidine, with the chemical formula C5H10ClN, exhibits interesting solubility characteristics that are noteworthy:

  • Polarity: Due to the presence of a chlorine atom and the amine group, 1-chloropiperidine is a polar compound.
  • Solvents: It is soluble in several organic solvents, including:
    • Water
    • Ethanol
    • Dichloromethane
  • Temperature Effects: Solubility may increase with temperature, which is a common trend observed in organic compounds.
  • Solubility Limits: The exact solubility parameters can depend on the presence of other solutes or solvents, as well as experimental conditions.

As a result, it is crucial to consider the conditions under which the solubility is being measured. In practical applications, 1-chloropiperidine is often enjoyed for its capacity to dissolve in both hydrophilic and lipophilic environments, making it a versatile compound in chemical syntheses.

Interesting facts

Interesting Facts about 1-Chloropiperidine

1-Chloropiperidine is an intriguing compound in the realm of organic chemistry. It is a halogenated derivative of piperidine, which is a cyclic amine known for its versatility in various chemical synthesis processes. Here are some engaging facts about 1-chloropiperidine:

  • Key Intermediate: 1-Chloropiperidine serves as an essential intermediate in the synthesis of various pharmaceuticals and agrochemicals, highlighting its industrial significance.
  • Diverse Applications: It is used in the synthesis of potential therapeutic agents targeting various neurological and cardiovascular disorders.
  • Substituent Influence: The introduction of the chlorine atom enhances the reactivity of the piperidine ring, making it a valuable target for further chemical modifications.
  • Synthesis Pathways: Chemists typically produce 1-chloropiperidine through nucleophilic substitution reactions, showcasing the elegance of organic synthesis techniques.
  • Solvent Properties: This compound is known to serve as a solvent for various organic reactions, proving its versatility in lab settings.
  • Safety Considerations: As with many halogenated compounds, it is essential to handle 1-chloropiperidine with care due to its potential toxicity and environmental impact.

Overall, 1-chloropiperidine exemplifies how a simple alteration in molecular structure can lead to significant changes in chemical behavior and application. Chemically adept individuals continue to explore the diverse possibilities that this compound offers in synthetic organic chemistry.

Synonyms
N-Chloropiperidine
1-Chloropiperidine
PIPERIDINE, 1-CHLORO-
DTXSID10175894
DTXCID1098385
2156-71-0
1-Chloro-Piperidine
4V5HK98PCN
UNII-4V5HK98PCN
1-CHLOROPIPERIDINE-
CHLOROPIPERIDINE, N-
SCHEMBL1262242
CIQJWKNJDQKPPO-UHFFFAOYSA-N
AKOS025149416
NCP
DB-199401
Q28410927