Skip to main content

1-Chloroacetone

ADVERTISEMENT
Identification
Molecular formula
C3H5ClO
CAS number
78-95-5
IUPAC name
1-chloropropan-2-one
State
State

At room temperature, 1-Chloroacetone is a liquid. Despite being a small organic compound, its halogen content attributes to it remaining liquid.

Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.15
Boiling point (Celsius)
119.00
Boiling point (Kelvin)
392.15
General information
Molecular weight
92.53g/mol
Molar mass
92.5250g/mol
Density
1.1540g/cm3
Appearence

1-Chloroacetone is typically a colorless liquid. It is known for its pungent odor. Being a halogenated ketone, it can grow yellowish over time due to impurities.

Comment on solubility

Solubility of 1-chloropropan-2-one

1-chloropropan-2-one, also known as acetone chlorohydrin or 1-chloro-2-propanone, exhibits notable solubility characteristics that are essential in various chemical processes.

  • It is miscible with water, meaning it can mix in any proportion without separating. This characteristic is crucial for its application in aqueous solutions.
  • Additionally, 1-chloropropan-2-one is soluble in many organic solvents, such as ethanol and diethyl ether. This property enhances its versatility in organic synthesis.
  • However, caution should be exercised when handling this compound due to its potential reactivity with other substances.

In general, the solubility of 1-chloropropan-2-one can be described as:

  1. High solubility in polar solvents: Its ability to dissolve in water underscores its polar nature.
  2. Compatible with non-polar solvents: While primarily polar, its solubility in non-polar solvents like hexane indicates some degree of interaction with non-polar phases as well.

In conclusion, the solubility of 1-chloropropan-2-one plays a vital role in its application in laboratories and industries, facilitating various chemical reactions and processes.

Interesting facts

Interesting Facts About 1-Chloropropan-2-one

1-Chloropropan-2-one, also known as isopropyl chloroacetate, is a noteworthy organic compound with a variety of applications in both the industrial and laboratory settings. Here are some fascinating aspects of this compound:

  • Synthesis: 1-Chloropropan-2-one can be synthesized through various methods, including the reaction of propan-2-one with thionyl chloride, showcasing its versatility in organic chemistry.
  • Reactivity: As a chlorinated compound, it exhibits unique reactivity patterns, making it an important intermediate in the synthesis of other chemical compounds, particularly in the pharmaceutical industry.
  • Applications: It serves as a key reagent in the preparation of α-halo ketones and is often used in the synthesis of herbicides and fungicides, revealing its significance in agriculture and pest control.
  • Toxicity Concerns: Like many chlorinated compounds, it is important to handle 1-chloropropan-2-one with care due to its toxicity. Understanding its safety profile is crucial for researchers and industrial workers.
  • Environmental Impact: The compound's stability and potential to persist in the environment highlight the need for ongoing studies into its biodegradation and ecological effects.

In summary, 1-chloropropan-2-one is an interesting compound due to its synthetic utility and reactivity, as well as its implications for safety and environmental science. As researchers continue to explore its properties, the discoveries made could pave the way for innovative applications across various fields.

Synonyms
Chloroacetone
1-Chloropropan-2-one
78-95-5
Chloropropanone
Monochloroacetone
1-Chloroacetone
Acetonyl chloride
Chloro-2-propanone
1-CHLORO-2-PROPANONE
Chloracetone
Chloromethyl methyl ketone
Tonite
Monochloracetone
2-Propanone, 1-chloro-
3-Chloro-2-propanone
Acetone, chloro-
1-Chloropropanone
Monochloropropanone
A-Stoff
alpha-Chloroacetone
1-Chloro-2-ketopropane
Chloracetone [French]
1-Chloro-2-oxopropane
.alpha.-Chloroacetone
NSC 30673
CCRIS 1943
1-chloro-propan-2-one
Chloroacetone, stabilized
HSDB 1070
chloromethylketone
EINECS 201-161-1
UN1695
BRN 0605369
DTXSID0021547
CHEBI:47220
NSC-30673
CHLOROACETONE [MI]
60ZTR74268
DTXCID101547
EC 201-161-1
4-01-00-03215 (Beilstein Handbook Reference)
1-CHLORO-2-PROPANONE [HSDB]
Cholroacetone
MONOCHLOROACETONE, (STABILIZED)
MONOCHLOROACETONE, [STABILIZED]
chloroactone
cloroacetone
chloro acetone
chloro-acetone
1Chloroacetone
chloro-propanone
Chloro2propanone
Acetone, chloro
UNII-60ZTR74268
1Chloro2propanone
3Chloro2propanone
isopropoyl chloride
1Chloro2oxopropane
Chlorinated acetone
1Chloro2ketopropane
1-Chloroacetone #
isopropanoyl chloride
MFCD00000936
2Propanone, 1chloro
Chloroacetone, 95%
UN 1695
propanone, 1-chloro-
CH3COCH2Cl
Chloroacetone (unstabilized) [Forbidden]
ClCH2COCH3
1-Chloro-propane-2-one
Monochloroacetone (unstabilized) [Forbidden]
Chloroacetone (unstabilized)
WLN: G1V1
2-PROPANONE, CHLORO-
Monochloroacetone (unstabilized)
CHEMBL1231084
NSC30673
Tox21_200027
BBL036265
STL185549
AKOS000119650
CAS-78-95-5
NCGC00166003-01
NCGC00166003-02
NCGC00257581-01
NS00008819
Chloroacetone, stabilized [UN1695] [Poison]
InChI=1/C3H5ClO/c1-3(5)2-4/h2H2,1H
Q425346
Chloroacetone, produced by Wacker Chemie AG, Burghausen, Germany, >=96.0% (GC)
201-161-1