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N-Chlorosuccinimide

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Identification
Molecular formula
C4H4ClNO2
CAS number
128-09-6
IUPAC name
1-chloropyrrolidine-2,5-dione
State
State
N-Chlorosuccinimide is in a solid state at room temperature. Due to its crystalline nature, it is handled typically as a granular or fine powder.
Melting point (Celsius)
151.00
Melting point (Kelvin)
424.00
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.00
General information
Molecular weight
133.54g/mol
Molar mass
133.5470g/mol
Density
1.6530g/cm3
Appearence

N-Chlorosuccinimide typically appears as a white to off-white crystalline solid. It is often available in powder form and is known for its distinctive sharp odor. The compound is quite stable when dry but hydrolyzes slowly in the presence of moisture.

Comment on solubility

Solubility of 1-Chloropyrrolidine-2,5-dione

1-Chloropyrrolidine-2,5-dione is an intriguing compound that presents unique solubility characteristics. Understanding its solubility behavior can enhance its application in various chemical processes. Here are some key points regarding its solubility:

  • Solvent Affinity: 1-Chloropyrrolidine-2,5-dione is generally soluble in polar solvents such as water and alcohols, owing to its polar functional groups.
  • Chemical Structure Influence: The presence of a chlorine atom in its structure can affect the solubility due to its electronegativity, potentially leading to increased interactions with solvents.
  • Temperature Effects: Like many organic compounds, the solubility of 1-chloropyrrolidine-2,5-dione may vary with temperature. An increase in temperature typically enhances solubility in most solvents.
  • Aqueous Solutions: Its solubility in water is notably significant, which makes it relevant for various applications in aqueous reactions.

In conclusion, the solubility of 1-chloropyrrolidine-2,5-dione is determined by factors such as solvent choice, temperature, and its unique molecular structure. As one might say, “The ability to dissolve reveals much about a compound’s potential.” Thus, exploring its solubility is crucial for optimizing its applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about 1-Chloropyrrolidine-2,5-dione

1-Chloropyrrolidine-2,5-dione is a fascinating compound that piques the interest of chemists due to its unique structural features and versatile applications. Here are some key highlights:

  • Structural Significance: This compound contains a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle. The presence of a chlorine atom adds to its reactivity, making it a subject of extensive research in synthetic chemistry.
  • Potential Applications: 1-Chloropyrrolidine-2,5-dione has potential applications in various fields, including medicinal chemistry. Derivatives of this compound may exhibit interesting biological activities, which could be beneficial in drug discovery.
  • Versatile Reagent: As a chlorinated compound, it can serve as a versatile reagent in organic synthesis, facilitating the formation of various other organic compounds through nucleophilic substitution reactions.
  • Research Interest: This compound is often studied for its role in the synthesis of amino acid derivatives and other biologically relevant molecules, highlighting its importance in the pharmaceutical industry.
  • Chirality Considerations: The presence of the pyrrolidine moiety also raises intriguing questions around chirality and enantiomeric purity, which are critical for the development of effective medications.

In summary, 1-chloropyrrolidine-2,5-dione is not just another chemical compound; it's a gateway to advanced research and a potential key player in future therapeutic agents. As a chemistry student or researcher, exploring its properties and applications could lead to exciting discoveries in the realm of organic and medicinal chemistry.

Synonyms
N-CHLOROSUCCINIMIDE
128-09-6
1-chloropyrrolidine-2,5-dione
Succinchlorimide
Chlorosuccinimide
Succinochlorimide
2,5-Pyrrolidinedione, 1-chloro-
Succinic N-chloroimide
1-Chloro-2,5-pyrrolidinedione
Succinic acid, imide, N-chloro-
NSC-8748
0FWP306H7X
DTXSID2042199
CHEBI:53203
DTXCID0022199
RefChem:163119
204-878-8
Succinimide, N-chloro-
NCS
C4H4ClNO2
MFCD00005511
NSC 8748
1-Chloro-2,5-pyrrolidine-dione
1-chloroazolidine-2,5-dione
Caswell No. 807
N-chloro-succinimide
N-Chloro succinimide
HSDB 5407
Succinchlorimide [NF]
EINECS 204-878-8
EPA Pesticide Chemical Code 077301
BRN 0113915
UNII-0FWP306H7X
AI3-52304
n-chlorsuccinimide
n-chorosuccinimide
N-chlorosuccinimid
N-chlorosucinimide
N-Clorosuccinimide
N-chlorosuccinirnide
N -chlorosuccinimide
N-chlorosuc-cinimide
N-Chlorosuccinimid e
2, 1-chloro-
SCHEMBL72
WLN: T5VNVTJ BG
N-chlorosuccinic acid imide
N-Chlorosuccinimide, 98%
5-21-09-00543 (Beilstein Handbook Reference)
SUCCINCHLORIMIDE [HSDB]
1-chloro-2,5 pyrrolidinedione
orb2664355
SCHEMBL5897812
SCHEMBL8158051
CHEMBL2107513
N-CHLOROSUCCINIMIDE [MI]
SUCCINCHLORIMIDE [MART.]
1-chloro-pyrrolidine-2,5-dione
NSC8748
1-chloro-pyrrolidine-2, 5-dione
BCP27379
HY-Y0532
Tox21_301368
BBL027530
SBB058749
STL194270
AKOS000121131
FC14779
PS-3219
NCGC00255991-01
BP-21326
CAS-128-09-6
DB-007755
NS00006599
ST51037890
EN300-25969
D78048
F005014
Q286192
F0001-0394
InChI=1/C4H4ClNO2/c5-6-3(7)1-2-4(6)8/h1-2H