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1-Cinnamyl-3-phenylazetidine

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Identification
Molecular formula
C18H19N
CAS number
59833-49-1
IUPAC name
1-cinnamyl-3-phenyl-azetidine
State
State
At room temperature, 1-Cinnamyl-3-phenylazetidine is typically in a liquid state due to its relatively low melting point and liquid appearance.
Melting point (Celsius)
37.00
Melting point (Kelvin)
310.15
Boiling point (Celsius)
335.40
Boiling point (Kelvin)
608.55
General information
Molecular weight
249.35g/mol
Molar mass
249.3490g/mol
Density
1.0850g/cm3
Appearence

This compound typically appears as a yellow oil.

Comment on solubility

Solubility of 1-Cinnamyl-3-phenyl-azetidine

1-Cinnamyl-3-phenyl-azetidine exhibits some intriguing solubility characteristics that are worth discussing. This compound, with its unique azetidine core and aromatic functionalities, tends to demonstrate the following solubility traits:

  • Solvent Dependence: The solubility of 1-cinnamyl-3-phenyl-azetidine can be influenced significantly by the solvent used. Non-polar and weakly polar solvents are generally more effective in dissolving such organic compounds due to their hydrophobic nature.
  • Temperature Sensitivity: As with many organic compounds, increasing the temperature can improve solubility. This phenomenon can be attributed to the increased kinetic energy facilitating the breakdown of intermolecular interactions.
  • Functional Group Interactions: The presence of the cinnamyl and phenyl groups may contribute to π-π stacking interactions, which could lead to decreased solubility in polar solvents. This phenomenon is often observed in compounds with substantial aromatic character.
  • Crystallinity: If the compound has a crystalline structure, solubility may be limited at room temperature if the lattice energy is high; breaking these interactions may require heating the solution.

Overall, while exact solubility information for 1-cinnamyl-3-phenyl-azetidine may be limited, it is expected to show a stronger affinity for non-polar solvents and can be influenced by temperature and structural interactions. Achieving solubility is crucial for various applications in pharmaceuticals and organic synthesis, making understanding these properties essential for chemists.

Interesting facts

Interesting Facts about 1-Cinnamyl-3-phenyl-azetidine

1-Cinnamyl-3-phenyl-azetidine is a fascinating compound that showcases the complexity and versatility of organic chemistry. Here are some engaging insights about this compound:

  • Structural Uniqueness: This compound features a four-membered ring structure known as an azetidine, which is relatively rare in organic molecules. The incorporation of a phenyl and cinnamyl group adds to its distinctive attributes.
  • Potential Applications: Compounds like 1-cinnamyl-3-phenyl-azetidine have potential applications in medicinal chemistry. Their unique structures can lead to various biological activities, making them candidates for drug development.
  • Synthetic Pathways: The synthesis of azetidine derivatives often involves intricate multi-step processes. Understanding these synthetic routes is crucial for chemists aiming to create new therapeutics or materials from this framework.
  • Reactivity: The azetidine ring can undergo various reactions, such as ring-opening, which can lead to the formation of more complex molecules. This feature is important for the development of new chemical entities.
  • Cultural Significance: The cinnamyl component connects this compound to the spice cinnamon, which has been treasured for its flavor and medicinal properties throughout history. This highlights the intersection of chemistry and cultural heritage.

As you explore the realm of 1-cinnamyl-3-phenyl-azetidine, remember that the world of chemistry is filled with endless possibilities and connections. The study of such compounds not only broadens our understanding of organic chemistry but also opens doors to innovative solutions in various fields.