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1-Cycloheptyl-3-(p-tolylsulfonyl)urea

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Identification
Molecular formula
C15H22N2O3S
CAS number
241125-95-7
IUPAC name
1-cycloheptyl-3-(p-tolylsulfonyl)urea
State
State

At room temperature, 1-Cycloheptyl-3-(p-tolylsulfonyl)urea is typically in a solid state. It is commonly handled in powder form and should be stored in a cool, dry place to maintain its stability and integrity.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
326.43g/mol
Molar mass
326.4320g/mol
Density
1.3100g/cm3
Appearence

This compound typically appears as a crystalline solid and its color can vary from white to off-white or slightly yellow, depending on the level of purity and specific batch characteristics.

Comment on solubility

Solubility of 1-Cycloheptyl-3-(p-tolylsulfonyl)urea

The solubility characteristics of 1-cycloheptyl-3-(p-tolylsulfonyl)urea exhibit notable features that reflect its chemical structure. This compound is typically considered to be moderately soluble in various organic solvents, but its solubility can be significantly influenced by factors such as temperature and the presence of distinct functional groups.

Key Points on Solubility:

  • Solvent Compatibility: 1-cycloheptyl-3-(p-tolylsulfonyl)urea shows a preference for polar organic solvents such as dimethyl sulfoxide (DMSO) and ethanol.
  • Temperature Effects: Increased temperature generally enhances the solubility of this compound, making it easier to dissolve in solution.
  • Ionic vs. Non-ionic Medium: Its solubility in an ionic medium can vary, as the sulfonyl group may interact differently with ions, affecting overall solubility.
  • Hydrophobic Interactions: The cycloheptyl moiety contributes to hydrophobic interactions, which can limit solubility in aqueous environments.

In summary, the solubility of 1-cycloheptyl-3-(p-tolylsulfonyl)urea may be described as conditional, largely governed by its molecular interactions and environmental factors. This makes understanding its solubility essential for applications in various chemical contexts.

Interesting facts

Exploring 1-Cycloheptyl-3-(p-tolylsulfonyl)urea

1-Cycloheptyl-3-(p-tolylsulfonyl)urea is an intriguing compound that plays a notable role in the field of medicinal chemistry. As a member of the urea family, it demonstrates a variety of functionalities that make it a promising candidate for pharmaceutical applications.

Key Features:

  • Versatile Applications: Compounds like this urea derivative are known for their potential use in therapeutic agents, particularly in the treatment of conditions such as cancer and inflammation.
  • Unique Structure: The presence of both a cycloheptyl and a p-tolylsulfonyl group contributes to its distinctive chemical properties, allowing for unique interactions in biological systems.
  • Research Potential: Studies reveal that modifications on urea structures can lead to diverse biological activities, making 1-cycloheptyl-3-(p-tolylsulfonyl)urea a focal point for investigations into drug design.

Scientific Context:

The sulfonamide group, present in the p-tolylsulfonyl moiety, is especially significant as it has been widely adopted for its antibacterial properties. This compound could represent a hybrid approach, combining both sulfonamide efficacy and urea versatility.

As a chemistry student or researcher, consider:

  • The potential side effects and metabolic pathways of such compounds in biological systems.
  • The synthesis methods that could be explored to optimize efficacy and reduce toxicity.
  • The implications of cycloalkane incorporation into drug design, influencing solubility and bioavailability.

In conclusion, 1-cycloheptyl-3-(p-tolylsulfonyl)urea stands out as a compound with diverse applications and interesting chemical behavior, making it a valuable subject in both theoretical and practical aspects of chemistry.

Synonyms
HEPTOLAMIDE
Heptolamida
Heptolamide [INN]
1034-82-8
Heptolamidum
UNII-459OHZ7GEN
1-Cycloheptyl-3-p-tolylsulfonylurea
459OHZ7GEN
1-Cycloheptyl-3-(4-methylphenylsulfonyl)urea
DTXSID30145817
DTXCID1068308
1-cycloheptyl-3-(4-methylphenyl)sulfonylurea
Oprea1_376839
SCHEMBL1814750
CHEMBL2104335
NS00124610
Q27258825