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Phenytoin

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Identification
Molecular formula
C15H12N2O2
CAS number
57-41-0
IUPAC name
1-cyclohexyl-3-phenyl-imidazolidine-2,4-dione
State
State
At room temperature, phenytoin is a solid. It is typically found in a crystalline powder form and is used in solid dosage formulations.
Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
332.00
Boiling point (Kelvin)
605.15
General information
Molecular weight
252.27g/mol
Molar mass
252.2680g/mol
Density
1.3000g/cm3
Appearence
Phenytoin appears as a white to off-white, crystalline powder. It is odorless but has a slightly bitter taste. The crystalline appearance is typical for this type of compound, reflecting its structured molecular configuration.
Comment on solubility

Solubility of 1-cyclohexyl-3-phenyl-imidazolidine-2,4-dione

1-cyclohexyl-3-phenyl-imidazolidine-2,4-dione is a fascinating compound whose solubility characteristics can be understood through various perspectives:

  • Polarity: The structure of this compound features both hydrophilic (polar) and hydrophobic (non-polar) components. The imidazolidine ring and the carbonyl groups contribute to its polar nature, which may enhance its solubility in polar solvents.
  • Common Solvents: It is generally observed that compounds with such hybrid characteristics often dissolve well in:
    • Alcohols (like ethanol and methanol)
    • Aromatic hydrocarbons (such as toluene)
    • Dimethyl sulfoxide (DMSO)
  • Solubility in Water: Based on its structure, this compound is expected to have limited solubility in water due to the bulky cyclohexyl and phenyl groups that impede interaction with water molecules.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, making it easier to incorporate into various solutions.

In summary, the solubility of 1-cyclohexyl-3-phenyl-imidazolidine-2,4-dione is predominantly influenced by its balance between polar and non-polar attributes, with a tendency towards solubility in organic solvents rather than in aqueous environments.

Interesting facts

Interesting Facts about 1-Cyclohexyl-3-phenyl-imidazolidine-2,4-dione

1-Cyclohexyl-3-phenyl-imidazolidine-2,4-dione, a compound belonging to the family of imidazolidine derivatives, exhibits a fascinating array of properties and potential applications that pique the interest of both chemists and pharmacologists.

Unique Structural Features

  • Imidazolidine Ring: The presence of the imidazolidine ring is noteworthy. This five-membered ring structure is known for its ability to stabilize various chemical functionalities.
  • Aromatic Phenyl Group: The phenyl group enhances the compound's electronic properties, which is crucial for its interaction with biological targets.
  • Cyclohexyl Group: The cyclohexyl group contributes to the compound's hydrophobic characteristics, influencing its solubility and bioactivity.

Potential Applications

This compound has drawn attention in the field of medicinal chemistry due to its potential therapeutic applications:

  • Pharmacological Research: Compounds with imidazolidine cores are often investigated for their effects on neurotransmitter systems, making them candidates for neuroprotective drugs.
  • Antioxidant Activity: There is evidence suggesting that similar imidazolidines exhibit antioxidant properties, which could be beneficial in managing oxidative stress-related diseases.
  • Structural Analogs: The unique structure provides a platform for designing various analogs that could enhance efficacy or target specificity.

Research Insights

Research on 1-cyclohexyl-3-phenyl-imidazolidine-2,4-dione is still in nascent stages, but preliminary studies suggest:

  • Biological Activity: The compound shows promise in modulating certain biological pathways, which may be leveraged in therapeutic contexts.
  • Chemical Stability: Its stability under various conditions makes it a favorable candidate for further investigations and applications.
  • Synergistic Effects: When used in combination with other compounds, it may enhance therapeutic outcomes due to synergistic effects.

As research continues, it is likely that further properties and applications of this compound will be uncovered, steering new innovations in both chemistry and medicine.

Synonyms
HYDANTOIN, 1-CYCLOHEXYL-3-PHENYL-
14395-03-0
GS 234
1-Cyclohexyl-3-phenylhydantoin
BRN 0888980
2,4-Imidazolidinedione, 1-cyclohexyl-3-phenyl-
DTXSID90162580
DTXCID1085071
2,4-Imidazolidinedione, 1-cyclohexyl-3-phenyl-(9CI)
5-24-05-00197 (Beilstein Handbook Reference)
1-cyclohexyl-3-phenylimidazolidine-2,4-dione
SCHEMBL29590229