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Cyclohexylphenylbarbital

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Identification
Molecular formula
C19H28N2O3
CAS number
77-16-1
IUPAC name
1-cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, Cyclohexylphenylbarbital is in a solid state. It is stable under normal temperature and pressure conditions.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
362.00
Boiling point (Kelvin)
635.15
General information
Molecular weight
304.39g/mol
Molar mass
304.3850g/mol
Density
1.1500g/cm3
Appearence

Cyclohexylphenylbarbital typically appears as a white crystalline solid. It is odorless but can have a slightly bitter taste. The compound is usually handled as a crystalline powder in laboratory settings.

Comment on solubility

Solubility of 1-cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione

The solubility of 1-cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione is influenced by several factors owing to its complex structure. Generally, solubility can be categorized based on the following considerations:

  • Polarity: As a compound featuring both cyclohexyl and bis-hydroxy functional groups, it exhibits a degree of polarity which may enhance its solubility in polar solvents, such as water and ethanol.
  • Hydrogen Bonding: The presence of the hydroxyl (-OH) group allows the compound to form hydrogen bonds, which can facilitate solubility in polar environments.
  • Environment: Solubility may vary significantly with temperature – higher temperatures usually increase solubility for most organic compounds.
  • Solvent Choice: It is likely to dissolve better in organic solvents like ethanol, acetone, and dimethyl sulfoxide (DMSO), compared to non-polar solvents.

In summary, while the solubility of 1-cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione in water may be limited due to the bulkiness of the cyclohexyl group, it stands to show increased solubility in polar organic solvents. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and materials science.

Interesting facts

Insights on 1-Cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione

This intriguing compound, 1-cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione, belongs to a class of compounds known as pyrimidines, which are essential in many biological processes. Here are some interesting aspects:

  • Structural Complexity: The compound features a hexahydropyrimidine core, showcasing a rich tapestry of chemical bonding, including fused rings that contribute to its unique characteristics.
  • Potential Biological Activity: Compounds with pyrimidine structures are often scrutinized for their pharmacological properties. They can act as vital components in medications, influencing processes like metabolism and cellular regulation.
  • Synthetic Applications: The versatility of this compound allows for various synthetic methodologies. It serves as a valuable intermediate in organic synthesis, paving the way for the development of more complex molecules.
  • Hydroxyl Groups: The presence of hydroxyl groups in the structure can enhance solubility and reactivity, often leading to increased biological activity. Such features make this compound a candidate for drug discovery research.
  • Study Significance: Understanding compounds like this is essential for chemists and pharmacologists alike, as they play a crucial role in the development of new therapeutic agents strategized to combat various health issues.

In summary, 1-cyclohexyl-5-(3-hydroxybutyl)hexahydropyrimidine-2,4,6-trione offers a glimpse into the sophisticated world of organic chemistry, revealing the possibilities that arise from its complex structure and functional groups. As we explore this compound further, we may unlock new doors in medicinal chemistry and biochemistry.

Synonyms
1-Cyclohexyl-5-(3-hydroxybutyl)barbituric acid
17148-44-6
1-cyclohexyl-5-(3-hydroxybutyl)-1,3-diazinane-2,4,6-trione
1-Cyclohexyl-5-(3-hydroxybutyl)perhydropyrimidine-2,4,6-trione
BARBITURIC ACID, 1-CYCLOHEXYL-5-(3-HYDROXYBUTYL)-
1-Cyclohexyl-5-(3-hydroxybutyl)-2,4,6-trioxoperhydropyrimidine
DTXSID50937993
3-Cyclohexyl-6-hydroxy-5-(3-hydroxybutyl)pyrimidine-2,4(3H,5H)-dione