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Cyclohexylmethylbarbituric acid

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Identification
Molecular formula
C12H20N2O3
CAS number
77-63-4
IUPAC name
1-cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, Cyclohexylmethylbarbituric acid is in a solid state. It is a stable compound commonly used in the pharmaceutical industry for its potent properties in CNS depression.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
390.80
Boiling point (Kelvin)
663.95
General information
Molecular weight
225.27g/mol
Molar mass
225.2720g/mol
Density
1.2845g/cm3
Appearence

This compound appears as a white crystalline powder. Its solid-state is typically characterized by a uniform and fine consistency, often resembling many other barbiturate derivatives.

Comment on solubility

Solubility of 1-Cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione

The solubility of a compound can often provide significant insight into its potential applications and behavior in various environments. For 1-cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione, the specific solubility characteristics are less documented, but we can consider some general factors that influence solubility in organic compounds:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents such as water.
  • Hydrophobicity: Conversely, larger hydrocarbon chains or rings, such as the cyclohexyl group in this compound, can lead to greater hydrophobic interactions, potentially decreasing solubility in polar solvents.
  • Hydrogen Bonding: The ability of the molecule to form hydrogen bonds can significantly affect its solubility in certain solvents.
  • Temperature: Solubility can also vary with temperature; often, higher temperatures can increase solubility.

As a result, while detailed solubility data may not be readily available for 1-cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione, one might hypothesize that its unique structure can lead to moderate solubility in organic solvents while being less soluble in water. To accurately determine the solubility, empirical measurements would be essential.

Interesting facts

Interesting Facts about 1-Cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione

1-Cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound with notable characteristics and applications. Here are some intriguing points to consider:

  • Unique Structure: This compound features a pyrimidine ring that is modified with cyclohexyl and methyl groups. Its complex structure contributes to its interesting chemical behavior.
  • Biological Activity: Compounds similar to 1-cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione have been studied for their potential pharmacological properties, including antibacterial and antifungal activities.
  • Synthesis Methods: The synthesis of this compound can involve various organic reactions, including cyclization and functional group modifications, which are essential for students of chemistry to explore.
  • Applications in Research: Researchers are interested in this compound for its possible applications in drug development and molecular biology, showcasing its relevance in the pharmaceutical industry.
  • Educational Value: The study of such compounds is beneficial for students as it provides insights into the principles of organic chemistry, including reaction mechanisms and the importance of substituents on reactivity.

In summary, 1-cyclohexyl-5-methyl-hexahydropyrimidine-2,4,6-trione serves as an excellent example of organic compounds that bridge the gap between fundamental chemistry and real-world applications. Its synthesis, properties, and biological relevance make it an intriguing topic for both scientific researchers and students alike.

Synonyms
834-90-2
1-Cyclohexyl-5-methylbarbituric acid
BRN 0887044
2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-cyclohexyl-5-methyl-
BARBITURIC ACID, 1-CYCLOHEXYL-5-METHYL-
1-Cyclohexyl-5-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione
SCHEMBL1426317
DTXSID901003391
3-Cyclohexyl-6-hydroxy-5-methylpyrimidine-2,4(3H,5H)-dione