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Cyclohexylphenobarbital

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Identification
Molecular formula
C16H22N2O3
CAS number
52-75-6
IUPAC name
1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione
State
State

This compound is typically found as a solid at room temperature.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
411.50
Boiling point (Kelvin)
684.65
General information
Molecular weight
318.36g/mol
Molar mass
318.4030g/mol
Density
1.2287g/cm3
Appearence

Cyclohexylphenobarbital is typically a white crystalline powder. It is known for being odorless and tasteless.

Comment on solubility

Solubility of 1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

The solubility of 1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione is an intriguing topic, as it presents unique characteristics due to its complex structure. Understanding the solubility of this compound can be broken down into several key points:

  • Polar and Nonpolar Interactions: The presence of both cyclohexyl and phenyl groups suggests that the compound may possess both polar and nonpolar characteristics, impacting its solubility in various solvents.
  • Solvent Dependence: This compound is likely more soluble in organic solvents such as ethanol or dichloromethane, compared to water, owing to the nonpolar nature of the cyclohexyl and phenyl groups.
  • Hydrogen Bonding: The functional groups within the hexahydropyrimidine ring may allow the compound to engage in hydrogen bonding with appropriate solvents, enhancing solubility in polar solvents.
  • Temperature Effects: Solubility can also be temperature dependent; increasing the temperature might improve solubility by increasing the kinetic energy of molecules.

In summary, while 1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione exhibits potential solubility in various solvents, a detailed empirical study would be necessary to determine precise solubility values. As with many organic compounds, one must consider the balance of polar and nonpolar interactions that ultimately dictate solubility behavior.

Interesting facts

Interesting Facts about 1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione

This unique compound, 1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione, belongs to a fascinating class of organic compounds characterized by a bicyclic structure featuring a pyrimidine ring. Here are some engaging insights about this intriguing compound:

  • Diverse Applications: Compounds similar to this one are often explored for their potential roles in medicinal chemistry. Their unique structures may lead to activities such as anti-inflammatory, anti-cancer, or anti-viral effects.
  • Synthetic Interest: The synthesis of this compound can involve various cyclization techniques, showcasing the ingenuity of organic chemistry. Such methods can help illustrate key principles of reaction mechanisms and the formation of complex structures.
  • Structure-Activity Relationship (SAR): Understanding how variations in the compound's structure influence biological activity is crucial. This may include altering substituents on the cyclohexyl or phenyl rings to enhance desired properties or lessen side effects.
  • Electronics and Resonance: The presence of electron-donating groups such as the phenyl ring can engage in resonance with the pyrimidine core, which may impact the reactivity and stability of the compound. This interplay is essential for predicting behavior during reactions.
  • Educational Impact: For students, studying this compound can enhance learning in areas such as stereochemistry and molecular geometry. It provides a practical example of how structural features correlate with chemical properties.

Overall, the exploration of 1-cyclohexyl-5-phenyl-hexahydropyrimidine-2,4,6-trione not only deepens our understanding of complex organic molecules but also opens pathways to potential therapeutic applications. The study of such compounds exemplifies the creativity and innovation inherent in the field of chemistry.

Synonyms
846-27-5
1-Cyclohexyl-5-phenylbarbituric acid
BRN 0759262
BARBITURIC ACID, 1-CYCLOHEXYL-5-PHENYL-
1-Cyclohexyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 1-cyclohexyl-5-phenyl-
SCHEMBL1639821
DTXSID501004878
3-Cyclohexyl-6-hydroxy-5-phenylpyrimidine-2,4(3H,5H)-dione