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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
134-11-2
IUPAC name
1-cyclohexyl-N-methyl-propan-2-amine
State
State

At room temperature, methamphetamine is usually found as a solid. In illicit use, it commonly appears as a crystalline solid in the form of a powder or crystals. When it appears as a crystalline substance, it is often referred to as "crystal meth."

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.20
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.20
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9440g/cm3
Appearence

Methamphetamine typically appears as a crystalline powder or in the form of coarse crystals. It is colorless to white in its pure form. When impure, it may appear in various colors, such as brown, yellow, red, or pink. In illicit form, especially as crystal meth, it is commonly found in large chunky crystals resembling ice or glass.

Comment on solubility

Solubility of 1-cyclohexyl-N-methyl-propan-2-amine

The solubility of 1-cyclohexyl-N-methyl-propan-2-amine can be explored through various factors that play a crucial role in its behavior in different solvents. Here are some key points to consider:

  • Polarity: This compound is relatively polar due to the presence of the amine group. Polarity influences solubility significantly; polar compounds tend to dissolve well in polar solvents.
  • Common Solvents: It may find good solubility in solvents such as water or ethanol, as these are capable of engaging in hydrogen bonding with the amine group.
  • Effect of Cyclohexyl Group: The bulky cyclohexyl group can hinder solubility to an extent due to steric effects, which might reduce interaction with solvent molecules.
  • Temperature: Generally, increasing the temperature may enhance the solubility of this compound, allowing for better interaction with solvents.
  • Concentration: At higher concentrations, solubility behaviors may shift, introducing potential precipitation or saturation points.

In summary, the solubility of 1-cyclohexyl-N-methyl-propan-2-amine is influenced by several factors, and understanding these aspects can assist in predicting its behavior in various chemical environments. As always, conducting specific solubility tests is advised for accurate measurements.

Interesting facts

Interesting Facts about 1-Cyclohexyl-N-methyl-propan-2-amine

1-Cyclohexyl-N-methyl-propan-2-amine, often referred to in a more abbreviated form, is a fascinating compound with several noteworthy aspects:

  • Chemical Structure: This compound belongs to the class of amines, which are derivatives of ammonia. Its structure features a cyclohexyl group, which contributes to its unique properties, making it a subject of interest in both organic chemistry and medicinal chemistry fields.
  • Potential Applications: Compounds like 1-cyclohexyl-N-methyl-propan-2-amine are studied extensively for their potential use in various therapeutic areas, particularly in the development of central nervous system stimulants. Researchers are keen on exploring its effects on neurotransmitter activity.
  • Research and Development: It has garnered attention in the pharmaceutical industry, being investigated for its potential role in treating mood disorders and enhancing cognitive function. As such, ongoing studies are aimed at understanding its mechanism of action and effects.
  • Synthetic Pathways: The synthesis of 1-cyclohexyl-N-methyl-propan-2-amine involves multiple steps that showcase the creativity and precision required in organic chemistry. The process may include the use of catalysts and various reagents, emphasizing the importance of reaction conditions.
  • Safety Precautions: While there is much excitement around this compound, it is vital to note that handling amines requires caution. Proper safety protocols are essential to prevent exposure and ensure safe laboratory practices.

In conclusion, 1-cyclohexyl-N-methyl-propan-2-amine stands out not only for its intriguing chemical structure but also for its potential applications in medical research. As scientists continue to explore the properties and effects of this compound, it holds promise for future innovations in therapeutic treatments.

Synonyms
Propylhexedrine
Benzedrex
Hydromethamphetamine
Propylhexedrin
Dristan
Obesin
Hexahydrodesoxyephedrine
Dristan Inhaler
CHP-Depot
101-40-6
Propilhexedrina
Propylhexadrine
Propylhexedrinum
1-cyclohexyl-N-methylpropan-2-amine
DL-propylhexedrine
Propilesedrina
Methyl-(1-methyl-2-cyclohexylethyl)amine
1-Cyclohexyl-2-(methylamino)propane
1-Cyclohexyl-N-methyl-2-propanamine
NSC 32410
1-Cyclohexyl-2-methylaminopropan
UNII-LQU92IU8LL
LQU92IU8LL
N,alpha-Dimethylcyclohexaneethylamine
EINECS 202-939-3
NSC-32410
BRN 3194303
(+-)-N,alpha-Dimethylcyclohexaneethylamine
(Cyclohexaneethyl)amine, N-alpha-dimethyl-
Cyclohexaneethanamine, N,.alpha.-dimethyl-
Propylhexedrine dl-form
beta-Cyclohexyl-isopropylmethylamin
(+/-) Propylhexedrine
EINECS 222-741-0
Propylhexedrinum [INN-Latin]
Propilhexedrina [INN-Spanish]
DTXSID1023526
CYCLOHEXANEETHYLAMINE, alpha,N-DIMETHYL-
Propylhexedrine [USP:INN:BAN]
3-12-00-00108 (Beilstein Handbook Reference)
NSC32410
(1-cyclohexylpropan-2-yl)(methyl)amine
NCGC00182042-01
Cyclohexaneethylamine, N-.alpha.-dimethyl-
Propylhexedrinum (INN-Latin)
Propilhexedrina (INN-Spanish)
PROPYLHEXEDRINE (MART.)
PROPYLHEXEDRINE [MART.]
Propylhexedrine (USP:INN:BAN)
cyclohexane, (2-methylamino)propyl-
PROPYLHEXEDRINE (USP MONOGRAPH)
PROPYLHEXEDRINE [USP MONOGRAPH]
Propilesedrina [DCIT]
1-Cyclohexyl-2-methylaminopropan [German]
beta-Cyclohexyl-isopropylmethylamin [German]
Cyclohexaneethanamine, N,alpha-dimethyl-, (+-)
Dristan inhaler (TN)
Cyclohexaneethanamine, N,alpha-dimethyl-
Propylhexedrine (USP/INN)
Cyclohexaneethanamine, N,alpha-dimethyl-, (+-)-
SCHEMBL28537
PROPYLHEXEDRINE [INN]
PROPYLHEXEDRINE [VANDF]
DTXCID303526
CHEMBL2105275
PROPYLHEXEDRINE [WHO-DD]
SCHEMBL20780004
WLN: L6TJ A1Y1&M1
CHEBI:134783
N-Methyl-1-cyclohexylisopropylamine
BENZEDREX09-19-2014
GAA19297
Tox21_113077
PROPYLHEXEDRINE DL-FORM [MI]
STK664138
AKOS005172629
.alpha.,N-Dimethylcyclohexaneethylamine
Cyclohexaneethanamine,.alpha.-dimethyl-
DB06714
N,.alpha.-Dimethylcyclohexaneethylamine
NCGC00182042-03
NCGC00182042-04
3595-11-7
CAS-101-40-6
N-.alpha.-(Dimethylcyclohexane)ethylamine
Cyclohexaneethylamine, .alpha.,N-dimethyl-
NS00078933
(Cyclohexaneethyl)amine, N-.alpha.-dimethyl-
D05637
EN300-135610
AB01331925-02
(+/-)-N,alpha-DIMETHYLCYCLOHEXANEETHANAMINE
(.+/-.)-N,.alpha.-Dimethylcyclohexaneethylamine
Q408704
(+/-)-N,.ALPHA.-DIMETHYLCYCLOHEXANEETHANAMINE
BRD-A35667010-001-01-8
Cyclohexaneethanamine, N,.alpha.-dimethyl-, (.+/-.)
202-939-3
222-741-0