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1-(Cyclohexylamino)propan-2-ol

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Identification
Molecular formula
C9H19NO
CAS number
3539-77-5
IUPAC name
1-(cyclohexylamino)propan-2-ol
State
State

1-(Cyclohexylamino)propan-2-ol can exist either as a liquid or solid at room temperature, depending on its purity and specific conditions. It is usually found as a liquid due to its melting point being close to room temperature.

Melting point (Celsius)
19.00
Melting point (Kelvin)
292.20
Boiling point (Celsius)
157.50
Boiling point (Kelvin)
430.60
General information
Molecular weight
157.24g/mol
Molar mass
157.2430g/mol
Density
0.9774g/cm3
Appearence

1-(Cyclohexylamino)propan-2-ol is typically a colorless to pale yellow liquid. It may also be available in a solid form under certain conditions. In its pure state, the liquid is clear and has a characteristic odor.

Comment on solubility

Solubility of 1-(cyclohexylamino)propan-2-ol

The solubility of 1-(cyclohexylamino)propan-2-ol can be characterized by several key factors:

  • Polarity: This compound contains both an amine group and a hydroxyl group, contributing to its polar nature, which generally enhances solubility in polar solvents.
  • Hydrogen Bonding: The presence of the hydroxyl (-OH) group allows 1-(cyclohexylamino)propan-2-ol to form hydrogen bonds with water, further aiding its solubility.
  • Non-Polar Characteristics: The cyclohexyl group introduces some non-polar character, which may affect solubility in highly polar solvents, leading to a balance in its overall solubility profile.

In summary, 1-(cyclohexylamino)propan-2-ol is expected to be moderately soluble in water due to its dual nature of hydrophilic and hydrophobic characteristics. As a general rule:

  1. It will dissolve well in polar solvents.
  2. Its solubility in non-polar solvents may be limited.

Understanding the solubility properties of such compounds is crucial for their applications in various fields, including pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about 1-(cyclohexylamino)propan-2-ol

1-(cyclohexylamino)propan-2-ol, often referred to in scientific circles for its intriguing structure and properties, is a notable compound in organic chemistry. This compound stands out for several reasons:

  • Pharmaceutical Relevance: It plays a role as an intermediate in the synthesis of various pharmaceuticals. Its unique amine functionality allows for diverse chemical transformations that contribute to drug development.
  • Structural Diversity: The presence of the cyclohexyl group adds a level of complexity to its chemical behavior, influencing solubility and interaction with biological targets.
  • Stereochemistry: The compound has chirality due to the presence of a stereocenter at the 2-position. This property is crucial as it can lead to different biological activities based on the enantiomer used.
  • Applications in Research: Beyond its pharmaceutical applications, it has been investigated in academic settings for studying amine reactivity and hydrogen bonding interactions within molecular frameworks.

Furthermore, scientists appreciate it for its potential to form hydrogen bonds, enhancing its interactions with other molecules. As one researcher noted, “the ability of 1-(cyclohexylamino)propan-2-ol to participate in multiple types of chemical bonding makes it an attractive candidate for further studies in synthesis and material science.”

In summary, 1-(cyclohexylamino)propan-2-ol exemplifies the fascinating interplay between structure and reactivity, making it a subject of interest for both students and seasoned chemists alike.

Synonyms
1-(cyclohexylamino)propan-2-ol
103-00-4
1-CYCLOHEXYLAMINO-2-PROPANOL
1-Cyclohexylaminopropan-2-ol
2-Propanol, 1-(cyclohexylamino)-
USAF DO-19
NSC 3179
EINECS 203-069-7
BRN 2072298
AI3-17435
1-(cyclohexylamino)-propan-2-ol
DTXSID60870443
4-12-00-00026 (Beilstein Handbook Reference)
1-cyclohexyl-amino-2-propanol
1-(cyclohexylamino)-2-propanol
NSC3179
WLN: L6TJ AM1YQ1
SCHEMBL183426
1-Cyclohexylamino-propan-2-ol
DTXCID80818165
AAA10300
NSC-3179
AKOS009006852
NS00041184
EN300-65482
G33141
Z90526999