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1-Cyclopropyl-3-phenylurea

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Identification
Molecular formula
C10H12N2O
CAS number
39500-41-7
IUPAC name
1-cyclopropyl-3-phenyl-urea
State
State

At room temperature, 1-Cyclopropyl-3-phenylurea is in a solid state. It has a crystalline structure which makes it stable under normal conditions, though it should be stored in a sealed container to prevent contamination and moisture uptake.

Melting point (Celsius)
184.00
Melting point (Kelvin)
457.15
Boiling point (Celsius)
284.40
Boiling point (Kelvin)
557.50
General information
Molecular weight
190.23g/mol
Molar mass
190.2310g/mol
Density
1.2014g/cm3
Appearence

1-Cyclopropyl-3-phenylurea typically appears as a white to off-white crystalline powder. It is generally odorless and has a relatively fine granulation depending on the method of synthesis and processing.

Comment on solubility

Solubility of 1-cyclopropyl-3-phenyl-urea

1-cyclopropyl-3-phenyl-urea is an interesting compound when it comes to solubility characteristics. Its solubility is influenced by its molecular structure, which includes both hydrophobic and hydrophilic components.

Key Points on Solubility:

  • Solvent Dependency: Generally, organic compounds like 1-cyclopropyl-3-phenyl-urea tend to be more soluble in organic solvents (e.g., ethanol, acetone) than in water.
  • Hydrogen Bonding: The presence of the urea group enables potential hydrogen bonding with polar solvents, which can enhance solubility.
  • Hydrophobic Interactions: The cyclopropyl and phenyl groups introduce hydrophobic characteristics that may limit solubility in highly polar solvents like water.

In summary, while 1-cyclopropyl-3-phenyl-urea shows some ability to dissolve in polar solvents due to hydrogen bonding, its hydrophobic parts may pose limitations on solubility in water. These solubility traits are crucial for its practical applications in various chemical and pharmaceutical fields.

Interesting facts

Interesting Facts about 1-Cyclopropyl-3-phenyl-urea

1-Cyclopropyl-3-phenyl-urea is a fascinating compound that has garnered attention in various fields of research due to its unique structural properties and potential applications. Here are some notable aspects of this compound:

  • Structural Innovation: The compound features a cyclopropyl group, which is a three-membered ring that influences the chemical reactivity and physical properties of the molecule. This structure can create unique steric effects that are important in medicinal chemistry.
  • Pharmacological Potential: Compounds with urea functional groups often demonstrate interesting biological activities. 1-Cyclopropyl-3-phenyl-urea is no exception, as it may possess antitumor and anti-inflammatory properties, making it a candidate for drug development.
  • Versatile Building Block: This compound can serve as a versatile building block in organic synthesis. Its ability to participate in various reactions can lead to the development of more complex molecules in pharmaceuticals and agrochemicals.
  • Research Interest: Scientists are continuously exploring the mechanisms of action for urea derivatives like this one. Understanding how such compounds interact with biological systems can lead to significant breakthroughs in drug discovery.
  • Previous Studies: Research has shown that modifications to the phenyl and cyclopropyl groups can greatly influence the compound's activity. This highlights the importance of structure-activity relationships (SAR) in optimizing its efficacy.

In summary, 1-cyclopropyl-3-phenyl-urea is not just another compound; it represents a convergence of chemistry and pharmacology, opening doors to new therapeutic possibilities. Its unique structure and biological implications make it a subject of ongoing scientific investigation and inter-disciplinary collaboration.

Synonyms
N-CYCLOPROPYL-N'-PHENYLUREA
13140-86-8
1-cyclopropyl-3-phenylurea
SCHEMBL751860
SCHEMBL752017
(cyclopropylamino)-N-benzamide
SCHEMBL7013534
SCHEMBL10825858
DTXSID80157026
STK466795
AKOS003292936
DB-404133
ST50929382
Z44603201