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Furfurylidenemalononitrile

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Identification
Molecular formula
C8H9N5O
CAS number
420-04-2
IUPAC name
1-(diaminomethylene)-2-(2-furylmethyl)guanidine
State
State

At room temperature, 1-(diaminomethylene)-2-(2-furylmethyl)guanidine is typically in a solid state.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
366.00
Boiling point (Kelvin)
639.15
General information
Molecular weight
181.20g/mol
Molar mass
181.1950g/mol
Density
1.3710g/cm3
Appearence

The compound typically appears as a crystalline solid. The appearance may range from a white to an off-white color, depending on purity and form.

Comment on solubility

Solubility of 1-(diaminomethylene)-2-(2-furylmethyl)guanidine

The solubility of 1-(diaminomethylene)-2-(2-furylmethyl)guanidine can be influenced by various factors including its molecular structure and the polarity of its functional groups. Generally, guanidine derivatives are known for their polar characteristics, which can enhance their solubility in polar solvents such as:

  • Water
  • Alcohols
  • Aqueous salt solutions

In contrast, they typically display lower solubility in non-polar solvents. The presence of both diamine and furyl moieties can also impact its solubility profile. As a result, one can expect the following:

  • Higher solubility in polar protic solvents due to hydrogen bonding.
  • Limited solubility in non-polar solvents owing to the hydrophobic nature of some components.
  • Temperature dependence where increased temperatures may enhance solubility.

In addition, compounds similar to 1-(diaminomethylene)-2-(2-furylmethyl)guanidine exhibit solubility characteristics that suggest ionic interactions could play a role in their dissolving behavior. This complex interplay of molecular interactions emphasizes the importance of considering both the functional groups present and the solvent environment when evaluating solubility.

Interesting facts

Interesting Facts about 1-(Diaminomethylene)-2-(2-furylmethyl)guanidine

1-(Diaminomethylene)-2-(2-furylmethyl)guanidine is a fascinating compound with unique structural features that enhance its chemical properties. Here are some intriguing aspects:

  • Structure-Activity Relationship: This compound contains both guanidine and furyl functional groups. The molecular structure allows for interesting interactions with biological systems, making it a subject of study in medicinal chemistry.

  • Biological Relevance: Several derivatives of guanidine compounds have been explored for their pharmacological activities, such as their antimicrobial and antiviral properties. This compound may thus exhibit similar potential.

  • Versatile Reactivity: The presence of the diamino group in this molecule enhances its nucleophilicity, allowing it to participate in various organic reactions, including condensation and substitution.

  • Sustainability in Research: The synthesis of furyl-containing compounds is gaining attention in green chemistry, as many derivatives are derived from renewable resources. This makes 1-(diaminomethylene)-2-(2-furylmethyl)guanidine a candidate for sustainable synthetic approaches.

  • Exploratory Applications: Due to its unique structural attributes, researchers are interested in investigating its potential applications in the development of novel therapeutics, agrochemicals, and functional materials.

In summary, 1-(diamino­methylene)-2-(2-furylmethyl)guanidine is more than just a chemical compound. Its intriguing properties and potential applications signify it as a compound worthy of deeper investigation in the realms of both chemistry and pharmacology.

Synonyms
Furfuryl Biguanide
7644-42-0
DTXSID30274696
DTXCID10226158
Maybridge1_003898
N-furfurylbiguanide
SCHEMBL6695378
CHEMBL5267818
WXIHLCZQQGEOKH-UHFFFAOYSA-N
NSC756972
NSC-756972