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Fluorophenylbiguanide

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Identification
Molecular formula
C8H11FN5
CAS number
156930-14-8
IUPAC name
1-(diaminomethylene)-2-(4-fluorophenyl)guanidine
State
State

At room temperature, fluorophenylbiguanide is in a solid state, often found as crystalline powder.

Melting point (Celsius)
106.50
Melting point (Kelvin)
379.70
Boiling point (Celsius)
289.10
Boiling point (Kelvin)
562.30
General information
Molecular weight
198.22g/mol
Molar mass
198.2140g/mol
Density
1.3200g/cm3
Appearence

Fluorophenylbiguanide typically appears as a white to off-white powder. The compound is stable under standard conditions but should be handled with care to prevent exposure to light and moisture.

Comment on solubility

Solubility of 1-(Diaminomethylene)-2-(4-fluorophenyl)guanidine

1-(Diaminomethylene)-2-(4-fluorophenyl)guanidine, a compound with intricate chemical properties, exhibits solubility traits that can influence its application and behavior in various environments. The solubility of this compound can be characterized by the following considerations:

  • Polarity: The presence of multiple amine groups (-NH2) in the guanidine structure enhances the compound's polarity, making it more likely to dissolve in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the amine groups significantly contributes to its solubility. This interaction allows the compound to engage with solvent molecules effectively.
  • Temperature Dependence: As with many organic compounds, the solubility may vary with temperature. Generally, an increase in temperature can lead to an increase in solubility.
  • pH Sensitivity: The solubility of this guanidine derivative can also be affected by the pH of the solution, as the protonation state of the amine functions changes in different pH environments.

In summary, solubility is an essential aspect of 1-(diaminomethylene)-2-(4-fluorophenyl)guanidine, impacted by multiple factors including polarity, hydrogen bonding, temperature, and pH conditions. Understanding these solubility characteristics is critical for researchers and practitioners working with this compound. As the saying goes, "Like dissolves like," and in this case, the polar nature of the compound suggests it will have a favorable interaction with polar solvents.

Interesting facts

Interesting Facts about 1-(Diaminomethylene)-2-(4-fluorophenyl)guanidine

1-(Diaminomethylene)-2-(4-fluorophenyl)guanidine, often referred to in research settings for its unique properties, is an intriguing compound that has captured the interest of chemists and biologists alike.

Biological Significance

This compound is notable for its function as a guanidine derivative. Guanidines are known to play important roles in biological systems, and compounds like this one can have implications in pharmacology and medicinal chemistry. Some key aspects include:

  • Potential Antimicrobial Activity: Studies suggest that guanidine derivatives may exhibit antimicrobial properties, making them candidates for developing new antibiotics.
  • Neuroprotective Effects: There is ongoing research into how similar compounds might protect neural tissues and assist in neurodegenerative conditions.

Chemical Properties

The guanidine functional group is characterized by its ability to form strong hydrogen bonds due to the presence of amino groups. This results in:

  • High Reactivity: The presence of amino groups makes this compound reactive, which is valuable in organic synthesis.
  • Involvement in Complex Formation: It can form complexes with various metal ions, which is useful in catalysis and material science.

Applications in Research

1-(Diaminomethylene)-2-(4-fluorophenyl)guanidine is also a subject of interest in various research fields:

  • Organic Synthesis: Its unique structure allows it to be a precursor in the synthesis of more complex molecules.
  • Pharmaceutical Development: Researchers are exploring its potential as a lead compound in drug development due to its promising biological activities.

In summary, 1-(Diaminomethylene)-2-(4-fluorophenyl)guanidine stands out not only for its intriguing chemical structure but also for its potential applications in health and technology. As with many chemical compounds, the full scope of its utility is still being unveiled, making it a fascinating subject for ongoing research.

Synonyms
16018-82-9
1-(diaminomethylidene)-2-(4-fluorophenyl)guanidine
Imidodicarbonimidic diamide, N-(4-fluorophenyl)-
N-(4-fluorophenyl)imidodicarbonimidic diamide hydrochloride
Maybridge1_006960
1-(4-Fluorophenyl)biguanide
SCHEMBL3674744
CHEMBL3628708
SCHEMBL19038540
DTXSID40274829
STK109870
AKOS001121939
NCGC00328460-01
N-(4-fluorophenyl)imidodicarbonimidic diamide
ST50106267
AB01324380-02
1-(Diaminomethylene)-2-(4-Fluorophenyl)Guanidine
amino{[(4-fluorophenyl)amino]iminomethyl}carboxamidine
1-{[{[AMINO(IMINO)METHYL]AMINO}(IMINO)METHYL]AMINO}-4-FLUOROBENZENE