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Metformin hydrochloride

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Identification
Molecular formula
C4H12ClN5
CAS number
110-57-6
IUPAC name
1-(diaminomethylene)-2-phenyl-guanidine;hydrochloride
State
State

At room temperature, Metformin hydrochloride is in a solid state. Its stability and efficacy make it a commonly used pharmaceutical compound.

Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
165.63g/mol
Molar mass
165.6250g/mol
Density
1.3300g/cm3
Appearence

Metformin hydrochloride typically appears as a white to off-white crystalline powder. It is odorless and hygroscopic in nature, meaning it can absorb moisture from the atmosphere. The compound is stable under recommended storage conditions but should be protected from light.

Comment on solubility

Solubility of 1-(diaminomethylene)-2-phenyl-guanidine;hydrochloride

The solubility of the compound 1-(diaminomethylene)-2-phenyl-guanidine;hydrochloride (C4H12ClN5) can be characterized as follows:

  • Water Solubility: This compound is generally soluble in water due to its ionic nature, attributed to the presence of the hydrochloride form.
  • Solvent Interaction: It can dissolve in polar solvents. The presence of amine groups contributes to its affinity for water.
  • Influencing Factors:
    • Temperature: Increased temperatures typically enhance solubility.
    • pH: Solubility may be affected by the pH of the solution, as protonation states can alter solubility.
  • Practical Application: The solubility in aqueous solutions makes it suitable for various biochemical applications and synthesis routes.

In conclusion, understanding the solubility characteristics of this compound is pivotal for its application in scientific research, where its stability and behavior in solution influence experimental outcomes.

Interesting facts

Interesting Facts about 1-(Diaminomethylene)-2-phenyl-guanidine Hydrochloride

1-(Diaminomethylene)-2-phenyl-guanidine hydrochloride is a fascinating compound that has garnered attention in various fields, particularly in medicinal chemistry. Here are some intriguing aspects to consider:

  • Role in Pharmacology: This compound is often explored for its potential pharmaceutical applications. Its structure suggests it may interact with various biological targets, making it a candidate for further research in drug development.
  • Versatile Functional Groups: The presence of multiple amine groups in its structure allows for a wide range of chemical reactivity. This versatility can lead to interesting derivatives and analogs, which may possess different biological activities.
  • Research Applications: Studies have indicated that guanidine derivatives can exhibit significant activity against various pathogens and potentially serve as novel therapeutic agents.
  • Mechanism of Action: The mechanism by which these guanidine compounds operate can involve interactions with enzyme systems, which is a key area of interest for researchers aiming to understand their efficacy in various biological systems.
  • Chemical Synthesis: The synthesis of 1-(diaminomethylene)-2-phenyl-guanidine hydrochloride can be accomplished through methods that highlight the fascinating chemistry of imines and guanidines, often incorporating innovative techniques in organic synthesis.

As you can see, 1-(diaminomethylene)-2-phenyl-guanidine hydrochloride is much more than just a chemical formula. Its unique properties and potential applications keep it at the forefront of chemical research, continuously inspiring scientists and students alike.

Synonyms
55-57-2
1-PHENYLBIGUANIDE HYDROCHLORIDE
N-Phenylimidodicarbonimidic diamide hydrochloride
Phenylbiguanide hydrochloride
1-Phenylbiguanide monohydrochloride
Phenyldiguanide hydrochloride
1-Phenylbiquanide hydrochloride
Phenylbiguanide monohydrochloride
N'-Phenylbiguanide monohydrochloride
MFCD00035040
Phenylbiguanide (hydrochloride)
Imidodicarbonimidic diamide, N-phenyl-, monohydrochloride
1-carbamimidamido-N-phenylmethanimidamide hydrochloride
N-Phenylbiguanide;PBG; 1-Phenylbiguanide
1-Phenylbiquanide HCl
NSC 3392
EINECS 200-239-2
AI3-14763
SR-01000075565
Phenylbiguanide Monohydrochloride; N'-Phenylbiguanide Monohydrochloride; N-Phenylimidodicarbonimidic Diamide Monohydrochloride; N-Phenylimidodicarbonimidic Diamide Hydrochloride; 1-Phenylbiguanide Monohydrochloride;
N-Phenylimidodicarbonimidic diamide monohydrochloride
N-Phenyl-imidodicarbonimidic diamide monohydrochloride
BIGUANIDE, 1-PHENYL-, MONOHYDROCHLORIDE
SPECTRUM1503641
WLN: MUYZMYUM&MR &GH
CHEMBL3039205
DTXSID1058763
Imidodicarbonimidicdiamide, N-phenyl-, hydrochloride (1:1)
N1-phenyl-biguanide hydrochloride
NSC3392
AAA05557
NSC-3392
CCG-40252
1-Phenylbiguanide hydrochloride, 98%
AKOS005170535
DS-3168
N-Phenylimidodicarbonimidic diamide HCl
NCGC00095920-01
NCGC00095920-02
PD000964
SY115355
CS-0021170
NS00078940
EN300-59552
N-Phenylimidodicarbonimidicdiamidehydrochloride
D78238
SR-01000075565-3
SR-01000075565-4
Z56762969
Imidodicarbonimidic diamide, N-phenyl-, hydrochloride (1:1)
200-239-2