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Metformin

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Identification
Molecular formula
C4H11N5
CAS number
657-24-9
IUPAC name
1-(diaminomethylene)-2-propyl-guanidine
State
State

At room temperature, Metformin is in the form of a solid.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
129.17g/mol
Molar mass
129.1660g/mol
Density
1.3380g/cm3
Appearence

Metformin appears as a white, crystalline powder. It is odorless and is known for its bitter taste. The compound is hygroscopic and is freely soluble in water.

Comment on solubility

Solubility of 1-(diaminomethylene)-2-propyl-guanidine

1-(diaminomethylene)-2-propyl-guanidine is quite an intriguing compound when it comes to its solubility characteristics. Understanding how a compound interacts with solvents is crucial for its applications in various fields. Here are some key points regarding the solubility of this compound:

  • Water Solubility: This compound is generally soluble in water due to its ability to form hydrogen bonds, primarily stemming from its guanidine functional group.
  • Polar Solvents: The presence of amino groups enhances its solubility in polar solvents, allowing for a wide range of potential uses in biochemical applications.
  • Organic Solvents: Contrarily, 1-(diaminomethylene)-2-propyl-guanidine is not soluble in non-polar organic solvents, which is typical for compounds containing significant polar character.
  • pH Effects: Solubility can also be influenced by pH; changes in the protonation state of the guanidine group can enhance or inhibit solubility in particular environments.

In summary, 1-(diaminomethylene)-2-propyl-guanidine exhibits notable solubility in aqueous and polar environments, while showing limited solubility in non-polar solvents. This solubility profile makes it a valuable compound in organic synthesis and medicinal chemistry, where its interactions with water-soluble environments are of particular interest.

Interesting facts

Interesting Facts about 1-(Diaminomethylene)-2-propyl-guanidine

1-(Diaminomethylene)-2-propyl-guanidine, often referred to in the scientific community as a unique guanidine derivative, possesses intriguing properties and applications that attract the attention of chemists and researchers alike. Here are some noteworthy aspects:

  • Biological Significance: This compound has been studied for its potential biological roles, especially as an inhibitor in various enzymatic reactions. Its guanidine structure allows for interaction with biological macromolecules, which can be vital in drug development.
  • Pharmaceutical Applications: The structural features of 1-(diaminomethylene)-2-propyl-guanidine make it a subject of interest in the pharmaceutical field. Researchers are exploring its potential in treating conditions like hypertension and heart failure by investigating its mechanism of action.
  • Research Implications: This guanidine derivative serves as a model compound in synthetic studies and helps in understanding the reactivity of guanidine derivatives in organic chemistry, which has broad implications in the synthesis of more complex molecules.
  • Therapeutic Targets: The ability of this compound to modulate certain biological pathways could lead to the development of new medicinal therapies, particularly in areas related to cardiovascular health and metabolic disorders.

In summary, 1-(diaminomethylene)-2-propyl-guanidine may not just be a simple organic compound; it harbors potential that could bridge the realms of organic chemistry and medicinal research. As one researcher noted, "The exploration of guanidine derivatives continues to unveil opportunities for innovative therapies that can improve human health."

Synonyms
propylbiguanide
SCHEMBL668625
SCHEMBL28170305
AKOS006341027
AKOS017407410