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Diethyl ethylmethylphosphonate

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Identification
Molecular formula
C8H19O3P
CAS number
22971-41-9
IUPAC name
1-diethoxyphosphoryl-2-methyl-pentan-3-one
State
State

At room temperature, diethyl ethylmethylphosphonate is typically found in a liquid state. Its liquid nature conforms to moderate temperatures, remaining stable and non-volatile under standard conditions without necessitating additional containment measures.

Melting point (Celsius)
-66.00
Melting point (Kelvin)
207.15
Boiling point (Celsius)
118.00
Boiling point (Kelvin)
391.15
General information
Molecular weight
180.19g/mol
Molar mass
180.1890g/mol
Density
1.0080g/cm3
Appearence

Diethyl ethylmethylphosphonate is a colorless liquid. It is often characterized by its clear and homogenous consistency, making it easily miscible with various organic solvents. It exhibits a typical liquid viscosity and is free of any visible particulates when in a pure state.

Comment on solubility

Solubility of 1-diethoxyphosphoryl-2-methyl-pentan-3-one

The solubility of 1-diethoxyphosphoryl-2-methyl-pentan-3-one, a compound featuring both phosphonate and ketone functionalities, can be intriguing due to its diverse interactions with solvents. Generally, its solubility characteristics can be influenced by the following factors:

  • Polarity: The presence of the diethoxyphosphoryl group enhances the compound's polarity, which may lead to greater solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The functional groups can participate in hydrogen bonding, further promoting solubility in polar environments.
  • Alkyl Chain Length: The hydrophobic character of the 2-methyl-pentan-3-one moiety may reduce solubility in highly polar solvents but could improve compatibility with organic solvents.

As a result, 1-diethoxyphosphoryl-2-methyl-pentan-3-one is expected to exhibit:

  • Good solubility in polar solvents like methanol and ethanol
  • Limited solubility in non-polar solvents such as hexane and toluene

In conclusion, the solubility profile of this compound can be complex, reliant on the balance between its polar and non-polar characteristics. Understanding these properties is vital for applications in chemistry and related fields.

Interesting facts

Interesting Facts About 1-Diethoxyphosphoryl-2-methyl-pentan-3-one

1-Diethoxyphosphoryl-2-methyl-pentan-3-one is a fascinating molecule that serves as an important point of study in synthetic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

  • Synthetic Applications: This compound features a diethoxyphosphoryl group, making it a valuable intermediate in the synthesis of various pharmaceuticals. Its unique structure allows chemists to explore new pathways for drug development.
  • Bioactivity: Research suggests that compounds similar to 1-diethoxyphosphoryl-2-methyl-pentan-3-one may exhibit significant biological activity. This opens up opportunities for discovery in areas like antiviral and antitumor research.
  • Phosphoryl Group Importance: The phosphoryl group is known for its ability to mimic natural phosphates, which plays a crucial role in biochemical processes. This allows for the exploration of interactions with biomolecules like proteins and nucleic acids.
  • Structure-Activity Relationship (SAR): The presence of the diethoxyphosphoryl moiety provides a rich ground for SAR studies, enabling scientists to understand how structural changes can influence biological activity.
  • Reactivity: The compound's reactivity can lead to interesting applications in organophosphorus chemistry, where modifications can yield derivatives with tailored properties.

As scientists continue to uncover the many facets of 1-diethoxyphosphoryl-2-methyl-pentan-3-one, its potential roles in both technology and medicine appear boundless. With ongoing research, this compound could contribute significantly to advancements in both synthetic methodologies and therapeutic strategies.

Synonyms
16965-90-5
DIETHYL (2-METHYL-3-OXOPENTYL)PHOSPHONATE
SCHEMBL7619464
DTXSID00937660