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1-Ethoxy-2-nitrobenzene

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Identification
Molecular formula
C8H9NO3
CAS number
2217-99-4
IUPAC name
1-ethoxy-2-nitro-benzene
State
State

At room temperature, 1-ethoxy-2-nitrobenzene is a liquid. It is typically used in research or industrial environments in this state.

Melting point (Celsius)
3.00
Melting point (Kelvin)
276.00
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.00
General information
Molecular weight
181.18g/mol
Molar mass
181.1760g/mol
Density
1.1545g/cm3
Appearence

1-Ethoxy-2-nitrobenzene appears as a pale yellow liquid. It is a clear compound without any suspended particles under normal conditions.

Comment on solubility

Solubility of 1-Ethoxy-2-nitro-benzene

1-Ethoxy-2-nitro-benzene, with the chemical formula C9H11NO2, exhibits specific solubility characteristics due to its unique molecular structure. When considering solubility, several important factors come into play:

  • Polarity: The presence of the nitro group (-NO2) contributes to the overall polarity of the compound, making it more soluble in polar solvents compared to non-polar ones.
  • Solvent Compatibility: 1-Ethoxy-2-nitro-benzene is expected to be soluble in common organic solvents such as ethanol, acetone, and dichloromethane. However, it has limited solubility in water due to its hydrophobic ethoxy group.
  • Temperature Dependency: Solubility can vary with temperature; typically, as temperature increases, the solubility of organic compounds in solvents like ethanol also increases.

In summary, while 1-ethoxy-2-nitro-benzene exhibits moderate solubility in polar organic solvents, its limited solubility in water is a key consideration for practical applications. Understanding these solubility traits is crucial for efficiently utilizing this compound in various chemical processes and formulations.

Interesting facts

Interesting Facts about 1-Ethoxy-2-nitro-benzene

1-Ethoxy-2-nitro-benzene is a fascinating compound that showcases the versatility of organic chemistry. Here are some intriguing aspects of this compound:

  • Structural Features: This compound consists of a nitro group (−NO₂) and an ethoxy group (−OCH₂CH₃) attached to a benzene ring, highlighting the ability of functional groups to influence the properties and reactivity of aromatic compounds.
  • Applications in Synthesis: 1-Ethoxy-2-nitro-benzene is often utilized in the synthesis of various organic materials, particularly in the production of dyes and pharmaceuticals. Its unique functional groups contribute to the creation of more complex molecules.
  • Electrophilic Aromatic Substitution: The presence of the nitro group makes the compound an excellent candidate for electrophilic aromatic substitution reactions, a fundamental reaction in organic synthesis. The nitro group is known to be a strong *deactivator* for further electrophilic attacks, but it also directs new substituents to the meta position, showcasing the nuanced behavior of substituents on aromatic systems.
  • Safety Considerations: As with many nitro compounds, safety protocols are essential when handling 1-ethoxy-2-nitro-benzene. Proper lab safety practices can mitigate risks associated with its potential toxicity and reactivity.
  • Environmental Impact: Understanding the behavior of compounds like 1-ethoxy-2-nitro-benzene can help in assessing their environmental impact. Research into their persistence and degradation in various environments is crucial for toxicology and environmental chemistry.

In summary, 1-ethoxy-2-nitro-benzene is more than just a chemical compound; it serves as a critical tool in synthetic organic chemistry and poses intriguing questions regarding its environmental and safety profiles. Its structure and reactive properties underline the interplay of functional groups in determining the behavior of organic molecules.

Synonyms
2-Nitrophenetole
1-Ethoxy-2-nitrobenzene
2-Ethoxynitrobenzene
Benzene, 1-ethoxy-2-nitro-
CCRIS 2331
NSC 5404
EINECS 210-232-6
UNII-Q0268PNU8K
BRN 2047308
Q0268PNU8K
AI3-00232
NSC-5404
NITROPHENETOLE, O-
DTXSID8060589
XGLGESCVNJSAQY-UHFFFAOYSA-
O-NITROBENZENE ETHYL ETHER
4-06-00-01250 (Beilstein Handbook Reference)
oNitrophenetole
oNitroethoxybenzene
Phenetole, onitro
1Ethoxy2nitrobenzene
Benzene, 1ethoxy2nitro
Ethyl onitrophenyl ether
DTXCID7042936
inchi=1/c8h9no3/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6h,2h2,1h3
xglgescvnjsaqy-uhfffaoysa-n
610-67-3
o-Nitrophenetole
PHENETOLE, o-NITRO-
Ethyl o-nitrophenyl ether
1-Ethoxy-2-nitro-benzene
MFCD00053603
NSC5404
CHEMBL167876
SCHEMBL2436211
AKOS006228945
AS-56771
N0489
NS00034551
A833029
Q27286833