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1-Ethoxy-2,2,2-trifluoroethanol

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Identification
Molecular formula
C4H7F3O2
CAS number
559-49-5
IUPAC name
1-ethoxy-2,2,2-trifluoro-ethanol
State
State
Liquid at room temperature.
Melting point (Celsius)
-80.70
Melting point (Kelvin)
192.45
Boiling point (Celsius)
99.40
Boiling point (Kelvin)
372.55
General information
Molecular weight
132.09g/mol
Molar mass
132.0890g/mol
Density
1.2508g/cm3
Appearence
1-Ethoxy-2,2,2-trifluoroethanol is a clear, colorless liquid with a mild odor.
Comment on solubility

Solubility of 1-Ethoxy-2,2,2-trifluoro-ethanol

1-Ethoxy-2,2,2-trifluoro-ethanol, with the formula C4H7F3O, exhibits notable solubility characteristics due to its unique structure. The presence of both the ethoxy group and the trifluoromethyl groups contributes to its solubility properties:

  • Polarity: The ethoxy group (-OCH2CH3) introduces polarity to the compound, making it more soluble in polar solvents.
  • Hydrogen Bonding: The hydroxyl group (-OH) enables the compound to engage in hydrogen bonding, which can enhance solubility in water.
  • Influence of Fluorine: The trifluoro group (-CF3) increases the overall electronegativity and effects such as dipole interactions, complicating solubility behavior in nonpolar solvents.

Overall, 1-ethoxy-2,2,2-trifluoro-ethanol tends to be soluble in a range of polar solvents, significantly in water due to hydrogen bonding capabilities. However, its solubility decreases in nonpolar solvents due to the repulsive nature of its polar functional groups compared to nonpolar ones. As a result, one might say: "The combination of hydrophilic and hydrophobic elements makes it a versatile yet intriguing compound in terms of solubility."

Interesting facts

Interesting Facts about 1-Ethoxy-2,2,2-trifluoroethanol

1-Ethoxy-2,2,2-trifluoroethanol is an intriguing chemical compound that belongs to the class of alcohols. Its unique structure and properties make it a subject of interest in various fields of study. Here are some engaging facts about this compound:

  • Fluorinated Surfactant: The presence of trifluoromethyl groups introduces remarkable properties, making it a potential candidate for use as a surfactant in formulations due to its ability to lower surface tension.
  • Green Chemistry: This compound can serve as a solvent in organic reactions, aligning with the principles of green chemistry by offering a more environmentally friendly alternative to traditional solvents.
  • Biological Applications: Research has shown that compounds like 1-ethoxy-2,2,2-trifluoroethanol may exhibit interesting biological activities, paving the way for future pharmaceutical applications.
  • Industrial Relevance: Its unique properties make it useful in the manufacturing of specialty chemicals, providing versatility in various chemical processes.
  • Layer of Complexity: The ethoxy group enhances its solubility, providing chemists with opportunities to explore its reactivity and interactions in different solvent systems.

Due to its distinct functional groups, 1-ethoxy-2,2,2-trifluoroethanol exemplifies how small changes in molecular structure can lead to significant variations in properties and applications. As quoted by noted chemists, "The essence of chemistry lies in understanding how the arrangement of atoms influences the behavior of substances." This compound serves as a perfect illustration of that principle, highlighting the complexity and beauty of chemical interactions.

In summary, 1-ethoxy-2,2,2-trifluoroethanol is more than just a chemical; it’s a gateway into the broader world of chemistry, encouraging further exploration into its potential uses and the significance of its structural features.

Synonyms
433-27-2
Trifluoroacetaldehyde ethyl hemiacetal
1-Ethoxy-2,2,2-trifluoroethanol
Fluoral ethyl hemiacetal
ETHANOL, 1-ETHOXY-2,2,2-TRIFLUORO-
TRIFLUOROACETALDEHYDEETHYLHEMIACETAL
EINECS 207-087-6
MFCD00000441
NSC 65431
BRN 0906797
Trifluoroacetaldehyde hemiethylacetal
DTXSID30870536
Trifluoroacetaldehyde Ethyl Hemiacetal (contains ca. 10% Ethanol)
1-ethoxy-2,2,2-trifluoroethan-1-ol
Trifluoroacetaldehyde ethyl hemiacetal (tech.)
1-ethoxy-2,2,2-trifluoro-ethanol
1-Ethoxy-2,2,2-trifluoro-ethanol; 1-Ethoxy-2,2,2-trifluoroethanol; Fluoral ethyl hemiacetal; NSC 65431
Perfluoroacetaldehyde Ethyl Hemiacetal
SCHEMBL613969
1-Ethoxy-2,2-trifluoroethanol
CHEMBL1979687
DTXCID50818253
NSC65431
trifluoroacetaldehyde ethylhemiacetal
NSC-65431
triflouroacetaldehyde ethyl hemiacetal
trifluoroacetaldehyde ethyl-hemiacetal
AKOS005254321
tri-fluoroacetaldehyde ethyl hemiacetal
BS-23878
NCI60_018864
Trifluoroacetaldehyde ethyl hemiacetal, 90%
2,2,2-trifluoroacetaldehyde ethyl hemiacetal
NS00043404
T0791
Trifluoroacetaldehyde ethyl hemiacetal, tech.
EN300-93419
F53519