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1-(Ethoxymethyl)piperidine

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Identification
Molecular formula
C8H17NO
CAS number
54882-84-1
IUPAC name
1-(ethoxymethyl)piperidine
State
State

At room temperature, 1-(Ethoxymethyl)piperidine is in a liquid state.

Melting point (Celsius)
-45.00
Melting point (Kelvin)
228.15
Boiling point (Celsius)
184.50
Boiling point (Kelvin)
457.65
General information
Molecular weight
157.24g/mol
Molar mass
157.2420g/mol
Density
0.9134g/cm3
Appearence

1-(Ethoxymethyl)piperidine is a colorless liquid. It may appear slightly yellowish if impure. The compound is typically free of any particulate matter and has a smooth, uniform appearance.

Comment on solubility

Solubility of 1-(ethoxymethyl)piperidine

1-(ethoxymethyl)piperidine, with the formula C9H19N, displays interesting solubility characteristics that are influenced by its chemical structure. Given its piperidine base, this compound has moderate solubility in various solvents:

  • Water: 1-(ethoxymethyl)piperidine is generally considered moderately soluble in water due to the presence of the ethoxy group, which can form hydrogen bonds with water molecules.
  • Organic Solvents: It shows a good level of solubility in many organic solvents such as ethanol, acetone, and dichloromethane, primarily due to its hydrophobic piperidine ring and the ethoxy group.
  • Solvent Interactions: The solubility can be influenced by factors such as temperature and the presence of other solutes, leading to variations in solubility under different conditions.

Understanding the solubility of 1-(ethoxymethyl)piperidine is crucial for its applications in pharmaceutical formulations and chemical processes. As with many organic compounds, the interaction between the solute and solvent is key; therefore, it is important to consider these factors when handling this compound in solution.

Interesting facts

Exploring 1-(ethoxymethyl)piperidine

1-(ethoxymethyl)piperidine is an intriguing compound that falls under the category of piperidine derivatives. This compound exhibits unique properties and functionalities that make it a subject of interest in various fields of chemistry.

Key Characteristics

  • Versatile Building Block: The structure of 1-(ethoxymethyl)piperidine can be modified to create a wide range of derivatives, which can lead to the discovery of new pharmaceuticals and organic compounds.
  • Biological Activity: Compounds similar to 1-(ethoxymethyl)piperidine are often evaluated for their potential biological activities, such as analgesic or anti-inflammatory properties, which can be beneficial in drug development.
  • Synthetic Applications: Chemists utilize this compound in the synthesis of complex organic molecules, making it valuable in both academic and industrial laboratories.

Scientific Importance

The study of 1-(ethoxymethyl)piperidine also opens up discussions on:

  • Structure-Activity Relationship (SAR): Understanding how variations in the compound's structure can affect its biological activity.
  • Mechanistic Insights: Investigating how this compound interacts at the molecular level can provide insights across chemistry and medicinal chemistry disciplines.
  • Pharmacophore Modeling: Utilized as a framework in drug design, where it can help in predicting the interactions of potential drug candidates.

In Summary

1-(ethoxymethyl)piperidine is more than just a simple chemical compound; it serves as a gateway to significant research avenues in medicinal chemistry and organic synthesis. As scientists continue to delve into its properties and potentials, this compound exemplifies the intricate relationships between chemical structure and biological function. Lautrec once said, "The only real voyage of discovery consists not in seeking new landscapes, but in having new eyes." This certainly rings true when exploring compounds like 1-(ethoxymethyl)piperidine!

Synonyms
N-(Ethoxymethyl)piperidine
PIPERIDINE, N-(ETHOXYMETHYL)-
N-Aethoxymethylpiperidin
3275-13-6
Piperidine, 1-(ethoxymethyl)-
NSC-507287
1-(Ethoxymethyl)piperidine
N-Aethoxymethylpiperidin [German]
NSC 507287
BRN 0103749
N-Aethoxymethylpiperidin [German]
ZH7LCV9KZ7
ethoxy-N-piperidinylmethane
1-(ethoxymethyl)pi-peridine
NCIOpen2_003536
WLN: T6NTJ A1O2
4-20-00-00849 (Beilstein Handbook Reference)
1-(Ethoxymethyl)piperidine #
SCHEMBL2016344
DTXSID40186418
IHQZMTASTVTDLX-UHFFFAOYSA-N
NSC507287