1-Ethyl-1-(1-naphthyl)isothiourea | Solubility of Things

Identification

Molecular formula

C₁₃H₁₄N₂S

CAS number

53648-05-0

IUPAC name

1-ethyl-1-(1-naphthyl)isothiourea

State

At room temperature, 1-ethyl-1-(1-naphthyl)isothiourea is a solid compound.

Melting point (Celsius)

144.00

Melting point (Kelvin)

417.15

Boiling point (Celsius)

409.15

Boiling point (Kelvin)

682.30

General information

Molecular weight

239.33g/mol

Molar mass

239.3400g/mol

Density

1.1812g/cm³

Appearence

1-Ethyl-1-(1-naphthyl)isothiourea typically appears as a solid with a crystalline structure. It is often off-white to pale yellow in color.

Comment on solubility

Solubility of 1-ethyl-1-(1-naphthyl)isothiourea

1-ethyl-1-(1-naphthyl)isothiourea is an intriguing compound when it comes to its solubility properties. Understanding the solubility of this compound can be crucial for its application in various fields, including pharmacology and chemical synthesis. Here are some key points to consider:

General Solubility Behavior: The compound is expected to exhibit limited solubility in water due to its hydrophobic naphthyl group.
Polar vs Nonpolar Solvents: It tends to have better solubility in organic solvents, such as ethanol and dimethyl sulfoxide (DMSO), which are capable of interacting with the polar characteristics of the isothiourea moiety.
Temperature Influence: Solubility can increase with temperature, reflecting a common trend in many organic compounds.
pH Effect: The solubility may vary with the pH of the solvent, influenced by the protonation state of the isothiourea functional group.

It is often said that "like dissolves like," and in the case of 1-ethyl-1-(1-naphthyl)isothiourea, its enhanced solubility in nonpolar solvents reflects this principle. Investigating its solubility in different media will provide further insights into its potential applications and behavior in various chemical processes.

Interesting facts

Interesting Facts about 1-Ethyl-1-(1-naphthyl)isothiourea

1-Ethyl-1-(1-naphthyl)isothiourea is a fascinating compound that belongs to the class of isothioureas, which are known for their diverse applications in biochemical research. This specific compound draws attention due to its unique structural features and properties.

Key Characteristics

Structural Significance: The presence of both ethyl and naphthyl groups in its structure contributes to its distinct reactivity and functional properties.
Biological Activity: Isothioureas, including this compound, often exhibit interesting biological activities. They have been studied for their potential roles in pharmacology, especially in relation to enzyme inhibition.
Research Applications: This compound has found applications in various research areas, particularly in the study of nitric oxide synthase and its regulation within biological systems.

Chemical Behavior

1-Ethyl-1-(1-naphthyl)isothiourea is known for its ability to interact with various biological targets due to its chemical structure. Here are some fascinating aspects of its behavior:

Stability: Isothiourea derivatives are often thermally stable, making them suitable for diverse experimental conditions.
Reactivity: The compound can undergo various chemical reactions, allowing researchers to modify its structure for enhanced biological activity.

Quote from the Field

A renowned chemist once said, "The beauty of isothioureas lies in their adaptability and the wealth of potential they hold for innovative drug design." This statement resonates well with the research conducted on 1-ethyl-1-(1-naphthyl)isothiourea, showcasing its promise as a valuable tool in medicinal chemistry.

Overall, 1-ethyl-1-(1-naphthyl)isothiourea is not just a compound to study; it represents a bridge between organic chemistry and biological applications, illustrating the interconnectedness of chemical research and real-world applications.