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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
1-ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea
State
State

At room temperature, Nitrofurazone is a solid substance, specifically existing as a crystalline powder. It remains stable under ordinary conditions, but should be stored in a well-sealed container to prevent exposure to excessive moisture and light.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1560g/mol
Density
1.6760g/cm3
Appearence

Nitrofurazone typically appears as a yellow, crystalline powder. It possesses a distinctive bright yellow color due to the presence of the nitrofuran moiety. The compound may also be characterized by its bitter taste and is often provided in powdered form for various applications.

Comment on solubility

Solubility of 1-ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea

The solubility of 1-ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea can be influenced by several factors due to its complex structure. Solubility is a crucial property that dictates how well a compound can interact in various solvents, and for this specific compound, the following points are noteworthy:

  • Polarity: The presence of the nitro group (-NO2) in the 5-position of the furan ring increases the overall polarity, potentially enhancing its solubility in polar solvents like water.
  • Hydrogen Bonding: The urea functionality in the structure allows for the possibility of hydrogen bonding with water molecules, promoting solubility.
  • Solvent Compatibility: While it is expected to be soluble in polar solvents, the compound may show reduced solubility in non-polar solvents due to its inherent characteristics.
  • Concentration Dependency: At different concentrations, the solubility behavior may vary significantly, which can be critical for applications, especially in synthesis or biological contexts.

Exploring the solubility profile of this compound not only reveals insights into its chemical behavior but also its potential applications in various fields. Pay close attention to the solvent choice as it can dramatically influence the effectiveness of the compound in various processes.

Interesting facts

Exploring 1-Ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea

1-Ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea is a unique compound, notable for its interesting chemical structure and potential applications. Here are some fascinating aspects:

  • Pharmacological Potential: This compound is part of a broader class of nitro compounds which often exhibit significant biological activity. The presence of the 5-nitro-2-furyl moiety suggests potential use in pharmaceuticals, particularly in the development of agents that can combat various diseases.
  • Chemical Interactivity: The unique functional groups within this compound allow for various chemical reactions. This means it could serve as a versatile building block in organic synthesis, especially in medicinal chemistry.
  • Research Insights: Scientists are intrigued by the properties of derivatives of this compound. Research continues to explore its reactivity and efficacy in potential applications, from therapeutic agents to agrochemicals.
  • Environmental Considerations: Like many compounds with nitro groups, there is a need to study the environmental impact of their use. Understanding how they interact with biological systems and the environment is crucial for sustainable development.

In addition to its potential uses, understanding the synthesis and reactivity of 1-Ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea can provide valuable insights into the design of new compounds with enhanced properties. As the field of medicinal chemistry evolves, compounds like this one may pave the way for innovative therapeutic solutions.

In the words of chemist Paul Dirac, “The theoretical physicist is like a mathematician, only more so.” This resonates in chemistry as well; the theoretical aspects of compounds like 1-Ethyl-1-[(5-nitro-2-furyl)methyleneamino]urea remind us of the intricate relationships between structure, function, and application.

Synonyms
BFE9UAV73M
Hydrazinecarboxamide, 1-ethyl-2-((5-nitro-2-furanyl)methylene)-
Nifursemizona
Etafurazone;NF161
5-Nitro-2-furaldehyde 2-ethylsemicarbazone
Nifursemizonum
Hydrazinecarboxamide, 1-ethyl-2-[(5-nitro-2-furanyl)methylene]-
2-Furaldehyde, 5-nitro-, 2-ethylsemicarbazone
UNII-BFE9UAV73M
NIFURSEMIZONE [INN]
Nifursemizone [USAN:INN]
NIFURSEMIZONE [USAN]
DTXSID30204357
NSC 186580
2-Ethyl-(5-nitrofuraldehyd)semicarbazon
Q27274643
1-Ethyl-2-((5-nitro-2-furanyl)methylene)hydrazinecarboxamide