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1-Ethyl-1-nitrosourea

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Identification
Molecular formula
C3H7N3O2
CAS number
759-73-9
IUPAC name
1-ethyl-1-nitroso-urea
State
State

At room temperature, 1-Ethyl-1-nitrosourea is typically in a solid state. It is important to store it under recommended conditions to maintain its stability.

Melting point (Celsius)
51.00
Melting point (Kelvin)
324.15
Boiling point (Celsius)
249.00
Boiling point (Kelvin)
522.15
General information
Molecular weight
133.12g/mol
Molar mass
133.1200g/mol
Density
1.1700g/cm3
Appearence

1-Ethyl-1-nitrosourea appears as a yellow to orange, crystalline solid. It may also be seen as a pale yellow powder in some instances. Like many nitroso compounds, it should be handled with care in a controlled environment.

Comment on solubility

Solubility of 1-ethyl-1-nitroso-urea

The solubility of 1-ethyl-1-nitroso-urea (C3H8N2O2) is an interesting aspect to explore, given its unique chemical composition. This compound demonstrates the following solubility characteristics:

  • Polar Solvent Interaction: 1-ethyl-1-nitroso-urea tends to be soluble in polar solvents such as water, due to its ability to form hydrogen bonds.
  • Non-Polar Solvent Behavior: It has limited solubility in non-polar solvents, which can be attributed to the hydrophilic nature of the urea functional group.
  • Temperature Effects: Solubility may increase with temperature, as is common with many solid solutes; however, specific data on the solubility gradient with temperature is essential for precise applications.

It is vital to consider that the solubility can be influenced by several factors, including:

  1. pH of the solution - where higher acidity may enhance solubility.
  2. The presence of other solutes that may either hinder or promote solubility through various chemical interactions.

In conclusion, the solubility of 1-ethyl-1-nitroso-urea is a multifaceted topic that underscores the interplay between its molecular structure and the solvent environment. Understanding this can be critical for its application in biochemical research and pharmaceutical development.

Interesting facts

Interesting Facts about 1-Ethyl-1-Nitroso-Urea

1-Ethyl-1-nitroso-urea is a fascinating compound with a variety of applications and a rich history in chemical research. Here are some key points about this intriguing substance:

  • Origin of the Name: The name 1-ethyl-1-nitroso-urea highlights its structure, which includes an ethyl group and a nitroso functional group attached to a urea backbone. This nomenclature indicates both its chemical composition and its uniqueness among urea derivatives.
  • Applications in Research: This compound has been widely used in molecular biology, particularly as a mutagen. Researchers employ it to induce mutations in organisms like bacteria, making it instrumental in understanding gene function and cellular processes.
  • Historical Context: It gained attention in the 1970s during studies exploring the mechanisms of mutagenesis. The ability of 1-ethyl-1-nitroso-urea to cause specific genetic changes has provided insights into cancer research and genetic engineering.
  • Safety Considerations: Due to its mutagenic properties, handling this compound requires stringent safety protocols. It underscores the importance of responsible laboratory practices and the need for protective equipment when working with such substances.
  • Chemical Properties: 1-Ethyl-1-nitroso-urea is a stable compound under certain conditions. However, it can decompose when exposed to heat or light, which presents a challenge for storage and usage in laboratory settings.

In summary, 1-ethyl-1-nitroso-urea stands out not just for its chemical structure but also for its profound impact on genetic research. As a versatile tool in the hands of scientists, it continues to contribute to our understanding of DNA and mutagenic processes, leaving a lasting mark on the fields of biology and chemistry.

Synonyms
1-Ethyl-1-nitrosourea
N-NITROSO-N-ETHYLUREA
N-Ethyl-N-nitrosourea
Ethylnitrosourea
Urea, N-ethyl-N-nitroso-
N-Nitrosoethylurea
NE-Urea
N-Ethyl-N-nitosourea
CCRIS 302
HSDB 5111
EINECS 212-072-2
BRN 1761174
DTXSID8020593
NSC-45403
DTXCID20593
1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine
ETHYL-1-NITROSOUREA, 1-
3-04-00-00233 (Beilstein Handbook Reference)
N-ETHYL-N-NITROSOUREA [MI]
NSC45403
N-ETHYL-N-NITROSOUREA [IARC]
N-NITROSO-N-ETHYLUREA [HSDB]
N-ETHYL-N-NITROSOUREA (IARC)
N Ethyl N nitrosourea
N-ethyl-N-nitrosocarbamide
NEthylnitrosourea
NNitrosoethylurea
NEUrea
NEthylNnitrosourea
1Ethyl1nitrosourea
Aethylnitrosoharnstoff
Urea, NethylNnitroso
1Ethyl1nitrosomocovina
Urea, 1ethyl1nitroso
NEthylNnitroso carbamide
Carbamide, NethylNnitroso
212-072-2
fusgacrlafqqrl-uhfffaoysa-n
759-73-9
Ethyl nitrosourea
N-Ethylnitrosourea
Nitrosoethylurea
N-Ethyl-N-nitroso-urea
Aethylnitroso-harnstoff
Aenh
Urea, 1-ethyl-1-nitroso-
N-Ethyl-N-nitroso carbamide
ENU
NSC 45403
RCRA waste number U176
Carbamide, N-ethyl-N-nitroso-
1-Ethyl-1-nitrosomocovina
N-Nitroso-N-ethyl Urea, Contains 40% water, 1.8 % AcOH
CHEBI:23995
P8M1T4190R
AENH [German]
ANH [German]
CAS-759-73-9
Aethylnitroso-harnstoff [German]
1-Ethyl-1-nitrosomocovina [Czech]
1-ethyl-1-nitroso-urea
RCRA waste no. U176
UNII-P8M1T4190R
WLN: ZVN2&NO
SCHEMBL77485
CHEMBL167667
N-Nitroso-N-ethylurea, ISOPAC(R)
Tox21_202151
Tox21_302749
N-Nitroso-N-ethylurea, Bulk package
AKOS006274354
HY-W019815
NCGC00090828-01
NCGC00090828-02
NCGC00256468-01
NCGC00259700-01
DB-221694
1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine #
NS00022760
C19178
EN300-206286
G29190
Q287629
Z1198149309
N-Nitroso-N-ethyl Urea, Contains 40per cent water, 1.8 per cent AcOH