Skip to main content

1-Ethyl-1-phenylguanidine hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C9H14ClN3
CAS number
2941-65-3
IUPAC name
1-ethyl-1-phenyl-guanidine;hydrochloride
State
State

At room temperature, 1-ethyl-1-phenylguanidine hydrochloride is generally in a solid crystalline form.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
301.00
Boiling point (Kelvin)
574.15
General information
Molecular weight
199.68g/mol
Molar mass
199.7100g/mol
Density
1.0665g/cm3
Appearence

1-Ethyl-1-phenylguanidine hydrochloride appears as a white to off-white crystalline solid. It may also be available in powder form and is typically highly soluble in water, forming a clear solution.

Comment on solubility

Solubility of 1-ethyl-1-phenyl-guanidine hydrochloride

1-ethyl-1-phenyl-guanidine hydrochloride is a chemical compound whose solubility characteristics are quite significant in its applications. Understanding its solubility can provide valuable insights into its behavior in various solvents.

Key Points about Solubility

  • Solvent Compatibility: This compound is generally soluble in water and polar organic solvents, making it versatile for use in different chemical environments.
  • pH Dependence: The solubility of 1-ethyl-1-phenyl-guanidine hydrochloride can be affected by the pH of the solution. Typically, its solubility may increase in acidic conditions due to the protonation of the guanidine group.
  • Temperature Influence: As with many ionic compounds, increasing the temperature can enhance the solubility of 1-ethyl-1-phenyl-guanidine hydrochloride, allowing for a more comprehensive formulation in various systems.

It is also noteworthy that the presence of electrolytes can impact the solubility of this compound in solution. As highlighted, “the interaction of solute and solvent molecules plays a critical role in determining solubility”, and this principle holds especially true for 1-ethyl-1-phenyl-guanidine hydrochloride.

Understanding these solubility factors is crucial for its effective application in pharmaceuticals and biochemistry, where precise concentrations are essential for the desired outcome.

Interesting facts

Exploring 1-Ethyl-1-Phenyl-Guanidine Hydrochloride

1-Ethyl-1-phenyl-guanidine hydrochloride is a fascinating compound that belongs to the class of guanidine derivatives, which are known for their diverse applications in both research and industry. Here are some remarkable facts about this compound:

  • Role in Biological Research: This compound plays a critical role in various biological studies, particularly in the field of neuroscience. It has been investigated for its potential as a modulator of nitric oxide synthase.
  • Pharmaceutical Potential: Given its structure, 1-ethyl-1-phenyl-guanidine hydrochloride has been explored in medicinal chemistry for its properties that can influence cardiovascular and neuroprotective activities.
  • Synthetic Versatility: The guanidine scaffold is quite versatile; numerous derivatives can be synthesized to optimize biological activity or to form conjugates with other therapeutic agents.
  • Mechanism of Action: Research studies have suggested that compounds like 1-ethyl-1-phenyl-guanidine hydrochloride may exert their effects through complex interactions with biological targets, including ion channels and receptors, emphasizing the need for detailed mechanistic studies.
  • Research Applications: It has attracted attention in various experimental protocols, particularly in the synthesis of other bioactive compounds due to its reactive nature.

As you explore the intricacies of 1-ethyl-1-phenyl-guanidine hydrochloride, consider how its study can enhance our understanding of chemical biology and lead to significant therapeutic advances. The compound's robust structure and reactivity indeed open up avenues for innovative research!

Synonyms
1-Ethyl-1-phenylguanidine hydrochloride
N-Ethyl-N-phenylguanidine hydrochloride
321-44-8
GUANIDINE, 1-ETHYL-1-PHENYL-, MONOHYDROCHLORIDE
DTXSID70185893
DTXCID10108384