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1-ethyl-2-nitrobenzimidazole

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Identification
Molecular formula
C9H9N3O2
CAS number
67567-96-8
IUPAC name
1-ethyl-2-nitro-benzimidazole
State
State

At room temperature, 1-ethyl-2-nitrobenzimidazole is in a solid state. It is typically found as a stable compound under normal laboratory conditions.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
191.19g/mol
Molar mass
191.1860g/mol
Density
1.2300g/cm3
Appearence

1-Ethyl-2-nitrobenzimidazole is a compound that typically appears as a crystalline solid. It may exhibit pale yellow to orange coloration depending on the sample purity and conditions, reflective of its aromatic nitro compound characteristics.

Comment on solubility

Solubility of 1-Ethyl-2-nitro-benzimidazole (C9H9N3O2)

1-Ethyl-2-nitro-benzimidazole is a compound that exhibits specific solubility characteristics worth noting. Here are some key points related to its solubility:

  • Solvent Dependence: The solubility of 1-ethyl-2-nitro-benzimidazole varies significantly depending on the solvent used. It is known to be more soluble in organic solvents compared to polar solvents.
  • Soluble in: Common organic solvents like ethanol and methanol can facilitate the dissolution of this compound effectively.
  • Limited Solubility in Water: Its solubility in water is generally low, which indicates a preference for hydrophobic environments. This low affinity for water leads to challenges in achieving sufficient concentrations in aqueous solutions.

As with many organic compounds, the degree of solubility can be heavily influenced by factors such as:

  • Temperature: Elevated temperatures often increase solubility.
  • pH Levels: Acidic or basic conditions may impact the ionization of the compound, thus affecting its solubility.
  • Presence of Co-solvents: The introduction of additional solvents may enhance overall solubility properties.

In summary, understanding the solubility of 1-ethyl-2-nitro-benzimidazole is crucial for applications in pharmaceuticals and chemical research, making it an intriguing topic of study in the field of chemistry.

Interesting facts

Interesting Facts about 1-Ethyl-2-nitro-benzimidazole

1-Ethyl-2-nitro-benzimidazole is a fascinating compound that belongs to the family of benzimidazoles, which are known for their diverse biological activities. Here are some key insights into this intriguing compound:

  • Pharmacological Interest: Benzimidazole derivatives, including 1-ethyl-2-nitro-benzimidazole, have garnered attention for their potential as pharmaceuticals. Many compounds in this class exhibit properties such as antifungal, antiviral, and anticancer activities.
  • Mechanism of Action: The mechanisms through which benzimidazoles exert their effects vary. Some operate by disrupting cellular processes or inhibiting specific enzymes essential for pathogen survival.
  • Environmental Insights: Studies on nitro-substituted compounds have revealed how they can affect environmental health, prompting research into their degradation, toxicity, and persistence in nature.
  • Selective Toxicity: One of the always-captivating discussions around benzimidazole derivatives is their ability to selectively target organisms. For example, they can be designed to differentiate between human cells and those of parasites or bacteria, making them highly valuable in therapy.
  • Platform for Synthesis: The structural framework of 1-ethyl-2-nitro-benzimidazole serves as an excellent platform for further chemical modifications, leading to a vast array of derivatives with potentially unique properties.

Moreover, the study of 1-ethyl-2-nitro-benzimidazole is a testament to the intricate relationship between structure and function in organic chemistry. As a chemist, one might find it particularly compelling to explore the challenges and achievements in synthesizing such compounds and determining their pathways in biological systems.

In summary, this compound embodies a rich blend of therapeutic potential, environmental significance, and synthetic versatility, making it a valuable subject of study in the realm of chemistry.

Synonyms
1-Ethyl-2-nitrobenzimidazole
BENZIMIDAZOLE, 1-ETHYL-2-NITRO-
10111-02-1
BRN 0913554
DTXSID10143735
5-23-06-00280 (Beilstein Handbook Reference)
DTXCID2066226
Benzimidazole, 1-ethyl-2-nitro- (7CI,8CI)
AKOS006280123
DB-285530