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1-ethyl-3-methyl-3-phenyl-azetidine

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Identification
Molecular formula
C11H17N
CAS number
32585-40-1
IUPAC name
1-ethyl-3-methyl-3-phenyl-azetidine
State
State

At room temperature, 1-ethyl-3-methyl-3-phenyl-azetidine is in a liquid state. It possesses a slightly amine-like odor typical of many nitrogen-containing organics.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.20
Boiling point (Celsius)
245.10
Boiling point (Kelvin)
518.30
General information
Molecular weight
175.27g/mol
Molar mass
175.2740g/mol
Density
1.0010g/cm3
Appearence

1-ethyl-3-methyl-3-phenyl-azetidine is a colorless to pale yellow liquid. The compound's appearance is consistent with many organic amines, characterized by a slightly oily texture.

Comment on solubility

Solubility of 1-ethyl-3-methyl-3-phenyl-azetidine

1-ethyl-3-methyl-3-phenyl-azetidine, a nitrogenous heterocyclic compound, exhibits interesting solubility characteristics that can be primarily attributed to its unique molecular structure.

In general, the solubility of compounds like this can be influenced by several factors:

  • Polarity: The presence of aliphatic and aromatic groups can affect the overall polarity, thereby influencing solubility in various solvents.
  • Hydrogen Bonding: The nitrogen atom in the azetidine ring may participate in hydrogen bonding, which can enhance solubility in polar solvents.
  • Hydrophobic Interactions: The phenyl group introduces hydrophobic characteristics, which may limit solubility in water, but improve solubility in non-polar solvents.

In practical terms:

  • It is expected to be more soluble in organic solvents such as ethanol, acetone, and dichloromethane.
  • Conversely, its solubility in water is likely to be quite limited due to hydrophobic regions in the molecule.

As a summary, the solubility of 1-ethyl-3-methyl-3-phenyl-azetidine can be described as:

  • A tendency for higher solubility in non-polar and polar aprotic solvents.
  • Limited solubility in water due to hydrophobic effects.

Understanding these solubility properties is essential for applications in pharmaceuticals and materials science, where solvent interactions can significantly impact reactivity and function.

Interesting facts

Interesting Facts about 1-Ethyl-3-methyl-3-phenyl-azetidine

1-Ethyl-3-methyl-3-phenyl-azetidine is a fascinating compound, especially in the realm of organic chemistry. This compound belongs to the class of azetidines, which are four-membered ring compounds featuring nitrogen atoms. Here are some intriguing aspects of this compound:

  • Structural Diversity: The unique combination of ethyl, methyl, and phenyl groups attached to the azetidine ring contributes to the compound's structural diversity. This can lead to variations in its chemical properties and reactivity.
  • Potential Applications: Compounds similar to 1-ethyl-3-methyl-3-phenyl-azetidine are explored for their potential in medicinal chemistry. Their unique structures may lead to the development of new pharmaceuticals with improved efficacy.
  • Chirality: The specific arrangement of substituents around the azetidine ring can result in chirality, giving rise to different enantiomers. This chirality can significantly influence the biological activity of the compound.
  • Reactivity: Azetidines, including this compound, can be involved in various chemical reactions such as nucleophilic substitutions and cyclization reactions, making them valuable intermediates in synthetic organic chemistry.
  • Research Interest: The exploration of azetidine derivatives has garnered attention in recent years, with studies focusing on their potential as building blocks for complex organic molecules.

As a student or scientist in the field, understanding compounds like 1-ethyl-3-methyl-3-phenyl-azetidine can broaden perspectives on molecular interactions and inspire innovative approaches in synthesis and application.

Synonyms
1-Ethyl-3-methyl-3-phenylazetidine
AZETIDINE, 1-ETHYL-3-METHYL-3-PHENYL-
L 1960
BRN 1425488
DTXSID50222492
DTXCID50144983
5-20-06-00368 (beilstein handbook reference)
7215-26-1
SCHEMBL25457063