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1-ethyl-3-phenylurea

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Identification
Molecular formula
C9H12N2O
CAS number
645-37-2
IUPAC name
1-ethyl-3-phenyl-urea
State
State

At room temperature, 1-ethyl-3-phenylurea is typically found in a solid state, characterized by its crystalline form.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
178.22g/mol
Molar mass
178.2150g/mol
Density
1.1400g/cm3
Appearence

1-ethyl-3-phenylurea typically appears as a crystalline solid. The crystals are usually white to off-white in color, giving them a somewhat pristine and clean appearance.

Comment on solubility

Solubility of 1-ethyl-3-phenyl-urea

1-ethyl-3-phenyl-urea, with the chemical formula C10H12N2O, exhibits interesting solubility characteristics that merit discussion:

  • Solvent Interactions: This compound is generally soluble in polar solvents and shows limited solubility in non-polar solvents. A key aspect of its solubility lies in its ability to form hydrogen bonds due to the presence of the urea functional group.
  • Temperature Effects: Like many organic compounds, the solubility of 1-ethyl-3-phenyl-urea can vary with temperature. Increased temperatures often lead to enhanced solubility.
  • Solubility in Water: While 1-ethyl-3-phenyl-urea has some solubility in water, it is considered to be only moderately soluble, making it necessary to consider alternative solvents for practical applications.
  • pH Influence: The solubility can also be affected by the pH of the solution, highlighting the importance of the ionic state of the compound in various environments.

In summary, understanding the solubility of 1-ethyl-3-phenyl-urea is crucial for its effective use in industrial and laboratory settings. The interactions with solvents and the environmental conditions play a significant role in its overall solubility profile.

Interesting facts

Interesting Facts about 1-Ethyl-3-phenyl-urea

1-Ethyl-3-phenyl-urea is a fascinating compound with diverse applications and interesting properties. Here are some key aspects to consider:

  • Pharmaceutical Relevance: This compound plays a significant role in medicinal chemistry. It is often studied for its potential as a pharmacological agent, particularly in the development of anti-diabetic drugs.
  • Urea Derivative: As a derivative of urea, it features a functional group that is crucial in biological systems. Urea itself is a product of protein metabolism and is widely recognized for its role in nitrogen disposal.
  • Interaction Studies: Researchers often focus on the interaction of 1-ethyl-3-phenyl-urea with various biological targets, enhancing our understanding of drug-receptor dynamics.
  • Synthesis Techniques: The compound can be synthesized via straightforward methods, making it an accessible target for organic chemists. Techniques often involve condensation reactions, which showcase the beauty of synthetic organic chemistry.
  • Solubility Considerations: This compound's solubility characteristics can determine its bioavailability and efficacy in pharmaceutical applications, highlighting the importance of studying its physical properties.

In summary, 1-ethyl-3-phenyl-urea is more than just a chemical entity; it serves as a bridge between sociological demands for better medical solutions and the profound complexities of chemical interactions in medicinal chemistry.

Synonyms
1-Ethyl-3-phenylurea
Urea, N-ethyl-N'-phenyl-
N-Phenyl-N'-ethylurea
UREA, 1-ETHYL-3-PHENYL-
N-Ethyl-N'-phenylurea
NSC 46782
BRN 2087534
90O3F38DTW
NSC-46782
UNII-90O3F38DTW
DTXSID90211143
4-12-00-00735 (Beilstein Handbook Reference)
DTXCID90133634
Urea, N-ethyl-N'-phenyl-(9CI)
623-064-7
xufxdodgxlvpnj-uhfffaoysa-n
621-04-5
1-phenyl-3-ethylurea
CHEMBL3235061
3-ethyl-1-phenylurea
NSC46782
MFCD00026696
SCHEMBL340246
BDBM50006452
STK083139
AKOS001303461
DB-054064
CS-0298621
Z44586347