Skip to main content

EPM

ADVERTISEMENT
Identification
Molecular formula
C26H30N2O2
CAS number
127792-27-6
IUPAC name
1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-pyrrolidin-2-one
State
State

EPM is typically a solid at room temperature. In its pure form, it is observed as crystalline in nature.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
585.80
Boiling point (Kelvin)
859.00
General information
Molecular weight
408.54g/mol
Molar mass
408.5420g/mol
Density
1.1852g/cm3
Appearence

EPM appears as an off-white solid compound. It can be seen in crystalline form, indicating its solid state at room temperature.

Comment on solubility

Solubility of 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-pyrrolidin-2-one

The solubility of the compound 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-pyrrolidin-2-one (C26H30N2O2) can be a fascinating aspect to explore due to its unique structure. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and chemical synthesis.

Factors Influencing Solubility

The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of multiple aromatic groups in the structure may lead to varying degrees of polarity, affecting how well it dissolves in different solvents.
  • Hydrophilicity/Hydrophobicity: The morpholino group suggests some hydrophilic characteristics, while the ethyl and diphenyl portions portray hydrophobic tendencies.
  • Temperature: Generally, solubility increases with temperature; thus, the behavior of this compound may vary in different thermal conditions.
  • Solvent Interaction: The choice of solvent plays a significant role. For instance, it may be more soluble in organic solvents than in water due to its overall structure.

Expected Solubility

Based on the aforementioned factors, it can be anticipated that:

  • The compound is expected to have moderate solubility in polar organic solvents.
  • Its aqueous solubility may be limited, aligning with the behavior of many diphenyl-pyrrolidine derivatives.

In conclusion, while precise solubility data may require empirical testing, the structural insights provide valuable guidance. As the famous saying goes, "Understanding the solubility of a compound is crucial for unlocking its potential." This compound, with its complex nature, offers an intriguing study in solubility science.

Interesting facts

Interesting Facts about 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-pyrrolidin-2-one

The compound 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-pyrrolidin-2-one showcases a fascinating intersection of organic chemistry and pharmaceutical applications. As a member of the pyrrolidinone class, this compound presents additional functionalities due to its complex structure, making it pertinent for various therapeutic studies.

Structural Complexity

  • Pyrrolidinone Ring: The presence of a pyrrolidinone moiety enhances the compound's ability to interact with biological targets, particularly in neuroscience.
  • Phenyl Groups: The two diphenyl groups contribute to the lipophilicity, assisting in the compound's ability to cross cell membranes, which is crucial for drug design.
  • Morpholine Functionality: The morpholinoethyl group can improve solubility and bioavailability, further exemplifying the careful design often utilized in medicinal chemistry.

Applications in Research

This compound is often explored for its potential neuroprotective effects and its ability to modulate neurotransmitter systems. Researchers investigate its efficacy as a:

  • Therapeutic Agent: There is growing interest in its possible applications in treating neurological disorders.
  • Research Tool: The structural attributes make it a valuable compound for studying specific receptor interactions.

Conclusion

In the world of drug development, compounds like 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-pyrrolidin-2-one serve as a reminder of the intricate designs woven into modern chemistry. As the scientific community continues to unveil the mysteries of such compounds, the potential for innovative therapies expands, highlighting the importance of both structure and function in chemistry.

Synonyms
doxapram
309-29-5
Dopram
1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-one
Doxapramum
Docatone
2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-
Doxapram [USP:JAN]
Doxapramum [INN-Latin]
1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone
HSDB 3318
CHEBI:681848
2-Pyrrolidinone, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-
1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one
EINECS 206-216-3
Doxapram (INN)
BRN 0628691
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-
UNII-94F3830Q73
AHR-619
94F3830Q73
DTXSID2022963
309-29-5 (free)
Doxapram (USP:JAN)
DOXAPRAM [INN]
Doxapramum (INN-Latin)
1-ethyl-4- (2-morpholin-4-ylethyl)- 3,3-diphenyl-pyrrolidin-2-one
Doxapram (USP:INN:BAN:JAN)
Doxapram [USP:INN:BAN:JAN]
1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone
C24H30N2O2
(+/-)-1-ETHYL-4-(2-MORPHOLINOETHYL)-3,3-DIPHENYL-2-PYRROLIDINONE
1-ETHYL-4-(2-(4-MORPHOLINYL)ETHYL)-3,3-DIPHENYL-2-PYRROLIDINONE
2-PYRROLIDINONE, 1-ETHYL-4-(2-(4-MORPHOLINYL)ETHYL)-3,3-DIPHENYL-, (+/-)-
Docatone (TN)
(+-)-doxapram
Doxapram [INN:BAN]
NCGC00167459-01
1-ethyl-4-(2-(morpholin-4-yl)ethyl)-3,3-diphenylpyrrolidin-2-one
Doxapram?
DOPREAM
(+/-)-doxapram
DOXAPRAM [HSDB]
DOXAPRAM [JAN]
DOXAPRAM [MI]
DOXAPRAM [VANDF]
DOXAPRAM [WHO-DD]
CHEMBL1754
Oprea1_016788
SCHEMBL644504
DTXCID002963
GTPL7169
R07AB01
HMS3886I17
BCP04484
HY-B0551
BDBM50505297
s5257
STK634791
AKOS005266711
BCP9000625
CCG-268390
DB00561
SB18932
AC-12510
AC-30628
AS-76170
DA-72893
BCP0726000068
NS00001120
C15540
D07873
EN300-123060
AB00698528-03
AB00698528_07
Q737743
BRD-A46179541-003-01-5
BRD-A46179541-311-02-0
BRD-A46179541-311-03-8
1-Ethyl-4-(2-morpholin-4-yl-ethyl)-3,3-diphenyl-pyrrolidin-2-one
1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone #
206-216-3