Interesting facts
Interesting Facts About 1-Ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic Acid
This compound is a member of the quinoline family, which is known for its importance in medicinal chemistry and the design of pharmaceuticals. Quinoline derivatives, particularly those with functional groups like fluorine or piperazine, often exhibit enhanced biological activity.
Key Characteristics
- Fluorine Substitution: The presence of fluorine atoms at the 6 and 8 positions significantly influences the compound's chemical properties, enhancing lipophilicity and metabolic stability.
- Piperazine Group: The 3-methylpiperazine moiety attached to this compound suggests potential applications in antipsychotic and antidepressant therapies due to the known activity of piperazine derivatives in these areas.
- Quinoline Ring: The quinoline nucleus is an important pharmacophore in many drugs, making this compound a valuable candidate for further research in drug development.
Furthermore, this compound may possess antimicrobial properties, as many quinolone derivatives are known for their efficacy against a range of bacteria. Research into this compound could also reveal potential applications in the treatment of various infections, showcasing its utility in the pharmaceutical landscape.
Potential Applications
- Antibacterial Agents: With the ongoing rise of antibiotic-resistant bacteria, novel compounds like this one are critical in the search for new antibiotics.
- Chemotherapy Adjuvants: The structure may lend itself to enhancing the effectiveness of existing chemotherapeutic agents.
- Diagnostic Agents: Potential applications in imaging or tracing biological pathways due to specific interactions with biomolecules.
As scientists continue to explore the unique attributes of this compound, it stands as a prime example of how structural modifications can lead to significant advancements in medicinal chemistry. In the realm of drug discovery, it's always exciting to see how compounds like this can lead to breakthroughs in our understanding and treatment of complex diseases!
Synonyms
lomefloxacin
98079-51-7
Lomefloxacine
Lomefloxacino
Lomefloxacinum
Lomefloxacine [French]
Lomefloxacino [Spanish]
Maxaquin
LFLX
Lomefloxacinum [Latin]
DM 10 (bactericide)
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
DM-10
SC-47111A
Lomefloxacin (USAN)
CCRIS 6305
CHEBI:116278
UNII-L6BR2WJD8V
L6BR2WJD8V
1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-ethyl-6-fluoranyl-8-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
Uniquin
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
BRN 4210041
(+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Lomefloxacin [USAN:INN:BAN]
Maxaquin (TN)
LOMEFLOXACIN [MI]
LOMEFLOXACIN [INN]
LOMEFLOXACIN [USAN]
LOMEFLOXACIN [VANDF]
LOMEFLOXACIN [WHO-DD]
DTXSID4040680
Okacin
Lomefloxacinum (Latin)
3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, (+-)-
SC 47111A
(+/-)-1-ETHYL-6,8-DIFLUORO-1,4-DIHYDRO-7-(3-METHYL-1-PIPERAZINYL)-4-
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
3-QUINOLINECARBOXYLIC ACID, 1-ETHYL-6,8-DIFLUORO-1,4-DIHYDRO-7-(3-METHYL-1-PIPERAZINYL)-4-OXO-, (+/-)-
Maxaquin (hydrochloride)
NY-198 (hydrochloride)
lomefloxacina
lomenfloxacin
SC-47111B (mesylate)
DAcalogiflox
SC-47111 (hydrochloride)
Lomefloxacin,(S)
MFCD00242673
Spectrum_001431
Prestwick0_000238
Prestwick1_000238
Prestwick2_000238
Prestwick3_000238
Spectrum2_000696
Spectrum3_001494
Spectrum4_000158
Spectrum5_001246
CHEMBL561
Epitope ID:119067
Lopac0_000678
SCHEMBL34609
BSPBio_000315
BSPBio_003107
KBioGR_000636
KBioSS_001911
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride
DivK1c_000365
SPBio_000851
SPBio_002236
BPBio1_000347
DTXCID2020680
GTPL12407
HY-B0455A
KBio1_000365
KBio2_001911
KBio2_004479
KBio2_007047
KBio3_002607
J01MA07
S01AE04
NINDS_000365
HMS2090O16
BCP11730
RKL10067
SC47111A
BDBM50417952
s5491
STL483414
AKOS015964770
CCG-204764
DB00978
KS-5014
SDCCGSBI-0050657.P004
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
1-ethyl-6,8-difluoro-7-(3-methylpiperazinyl)-4-oxohydroquinoline-3-carboxylic acid
IDI1_000365
SMP1_000287
NCGC00015603-02
NCGC00015603-03
NCGC00015603-04
NCGC00015603-05
NCGC00015603-07
NCGC00015603-16
NCGC00162221-01
NCGC00178293-01
NCGC00178293-02
FL170160
SBI-0050657.P003
Lomefloxacin 1000 microg/mL in Acetonitrile
NS00007577
C07078
D02318
G85922
AB00053622-04
AB00053622-05
AB00053622_06
AB00053622_07
EN300-18553898
Q203618
BRD-A75850590-003-05-6
BRD-A75850590-003-06-4
BRD-A75850590-003-09-8
BRD-A75850590-213-01-0
(+/-)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid hydrochloride
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo- (+/-)
Solubility of 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
The solubility of 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid (C17H18FN3O3) can be described as follows:
Understanding the solubility behavior of this compound is essential because it plays a crucial role in its bioavailability and application in pharmaceuticals. Considering the factors outlined above, it would be reasonable to predict that the solubility characteristics of this compound will present a unique challenge during formulation.