Skip to main content

Ertugliflozin

ADVERTISEMENT
Identification
Molecular formula
C22H25ClO7S
CAS number
1210344-57-2
IUPAC name
1-ethyl-N-[2-hydroxy-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-propyl-pyrrolidine-2-carboxamide
State
State

At room temperature, Ertugliflozin is a solid.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
873.15
Boiling point (Kelvin)
600.00
General information
Molecular weight
436.96g/mol
Molar mass
436.5300g/mol
Density
1.5600g/cm3
Appearence

Ertugliflozin is typically described as a white to off-white crystalline powder.

Comment on solubility

Solubility Overview

The compound 1-ethyl-N-[2-hydroxy-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-propyl-pyrrolidine-2-carboxamide, with its complex structure, reveals interesting solubility characteristics.

General Solubility Characteristics

Solubility is a critical property that can influence the behavior and applications of a compound in various environments. Here are some key points regarding the solubility of this compound:

  • Hydrophilicity and Hydrophobicity: The presence of multiple hydroxyl (-OH) groups suggests that this compound may be more hydrophilic, promoting solubility in polar solvents such as water.
  • Influence of Functional Groups: The carboxamide and hydroxyl functionalities are known for enhancing solubility due to their ability to form hydrogen bonds.
  • Tetrahydropyran Structure: The cyclic ether structure can impart some lipophilic characteristics; however, the competing hydrophilic groups could balance this effect.
  • Solvent Compatibility: Likely soluble in a range of solvents including water, alcohols, and possibly some organic solvents due to its diverse functional groups.

Influencing Factors

Several factors can influence the solubility of this compound:

  • Temperature: An increase in temperature typically enhances solubility for most solids.
  • pH Levels: The solubility can be affected by the pH of the solution, particularly for the carboxamide moiety.
  • Concentration: Higher concentrations of solutes can lead to precipitation, which can impact the effective solubility.

In conclusion, while this compound's specific solubility in various solvents may require experimental determination, its functionality indicates a propensity for enhanced solubility in polar media, highlighting its potential utility in pharmaceutical formulations and other applications.

Interesting facts

Exploring 1-Ethyl-N-[2-hydroxy-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-propyl-pyrrolidine-2-carboxamide

The compound 1-ethyl-N-[2-hydroxy-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-propyl-pyrrolidine-2-carboxamide is a fascinating example of organic chemistry that showcases a blend of structural complexity and potential biological significance. Here are some interesting insights into this unique compound:

  • Structural Complexity: This compound features multiple functional groups, including an amino acid derivative and a tetrahydropyran structure, which contribute to its intricate molecular architecture.
  • Potential Biological Activity: The presence of hydroxyl groups suggests that this compound may exhibit antioxidant properties. Researchers often investigate its potential in pharmaceuticals or nutraceuticals.
  • Synergistic Effects: The combination of functionalities, like the -NH- (amide) and -OH (hydroxyl) groups, could lead to synergistic interactions that enhance biological activity, making it an exciting target for further research.
  • Natural Product Inspired: The structure resembles that of various naturally occurring compounds found in plants and fungi, which are known for their health benefits. This raises questions about its possible sources and analogs in nature.

As researchers continue to investigate this compound, it opens up avenues for new discoveries in drug design and the understanding of complex biochemical pathways. It stands as a testament to the fascinating and diverse world of chemical compounds, inviting further exploration both in terms of synthesis and potential applications.

Synonyms
1-ethyl-N-[2-hydroxy-1-(3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl)propyl]-4-propylpyrrolidine-2-carboxamide
23298-12-6
DTXSID00878463
DTXSID30274939
D-ERYTHRO-ALPHA-D-GALACTO-OCTOPYRANOSIDE DERIVAT