Skip to main content

o-Fluorobenzotrifluoride

ADVERTISEMENT
Identification
Molecular formula
C7H4F4
CAS number
88-15-3
IUPAC name
1-fluoro-2-(trifluoromethyl)benzene
State
State

The compound is a liquid at room temperature.

Melting point (Celsius)
-33.00
Melting point (Kelvin)
240.15
Boiling point (Celsius)
102.30
Boiling point (Kelvin)
375.45
General information
Molecular weight
162.11g/mol
Molar mass
162.1100g/mol
Density
1.3320g/cm3
Appearence

o-Fluorobenzotrifluoride is a colorless liquid with a distinctive aromatic odor. It is often used as a solvent and an intermediate in organic chemical synthesis.

Comment on solubility

Solubility of 1-Fluoro-2-(trifluoromethyl)benzene

1-Fluoro-2-(trifluoromethyl)benzene, known for its unique structure, exhibits interesting solubility characteristics:

  • Polarity: The presence of both fluorine atoms and benzene as a hydrophobic structure contributes to its overall polarity. While the trifluoromethyl group (–CF3) is highly electronegative, its bulky nature can limit interactions with polar solvents.
  • Solvent Compatibility: This compound is less soluble in water due to its hydrophobic character. Instead, it displays better solubility in organic solvents such as ethanol, acetone, and dichloromethane.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature, making it more effective in elevated temperature settings.

In summary, while 1-fluoro-2-(trifluoromethyl)benzene has limited solubility in water due to its non-polar characteristics, it is capable of dissolving well in various organic solvents, highlighting the importance of matching solvent properties to solute behavior.

Interesting facts

Interesting Facts About 1-fluoro-2-(trifluoromethyl)benzene

1-fluoro-2-(trifluoromethyl)benzene, commonly referred to as a fluorobenzene derivative, holds a significant role in the field of organic chemistry due to its unique electronic and steric properties. Here are some fascinating aspects of this compound:

  • Reactivity: The presence of fluorine atoms in the structure enhances the reactivity of the molecule, making it a valuable intermediate in various chemical reactions, such as electrophilic aromatic substitution.
  • Applications: This compound is widely used in the synthesis of pharmaceutical compounds and agrochemicals. Its unique structure allows for tailored interactions with biological targets.
  • Regioselectivity: The substituent effects of the fluorine atoms can significantly influence the regioselectivity during chemical reactions, allowing chemists to control the direction of the reactions more effectively.
  • Synthetic Pathways: Researchers have developed multiple synthetic pathways to produce this compound, demonstrating its importance in synthetic organic chemistry.
  • Fluorinated Compounds: Compounds containing fluorine are often characterized by their lower polarity and higher thermal stability, which can be advantageous in various applications.

Overall, 1-fluoro-2-(trifluoromethyl)benzene serves as a fascinating example of how fluorinated compounds can alter chemical behavior and pave the way for advanced developments in chemistry and materials science.

Synonyms
2-Fluorobenzotrifluoride
392-85-8
1-Fluoro-2-(trifluoromethyl)benzene
o-Fluorobenzotrifluoride
1-FLUORO-2-TRIFLUOROMETHYLBENZENE
Benzene, 1-fluoro-2-(trifluoromethyl)-
alpha,alpha,alpha,2-Tetrafluorotoluene
MFCD00000374
NSC 10314
o,alpha,alpha,alpha-Tetrafluorotoluene
EINECS 206-880-4
DTXSID6059940
1-fluoro-2-trifluoromethyl-benzene
Benzene, fluoro(trifluoromethyl)-
alpha,alpha,alpha,Ar-Tetrafluorotoluene
NSC10314
o-trifluoromethylfluorobenzene
SCHEMBL169053
2-Fluorobenzotrifluoride, 99%
DTXCID9039606
2-fluoro-(trifluoromethyl)benzene
JHDLVVSXLOTMIE-UHFFFAOYSA-N
NSC-10314
1-fluoro-2-(trifluoromethyl)-benzene
o,.alpha.,.alpha.-Tetrafluorotoluene
AKOS009158358
CS-W016093
Toluene,.alpha.,.alpha.,o-tetrafluoro-
AC-23630
PS-11776
DB-330347
F0389
NS00042660
EN300-61892
o,.alpha.,.alpha.,.alpha.-Tetrafluorotoluene
Toluene, .alpha.,.alpha.,.alpha.,o-tetrafluoro-
Toluene, o,.alpha.,.alpha.,.alpha.-tetrafluoro-
Z975844608