Skip to main content

1-Fluoro-3-nitrobenzene

ADVERTISEMENT
Identification
Molecular formula
C6H4FNO2
CAS number
403-03-8
IUPAC name
1-fluoro-3-nitro-benzene
State
State

At room temperature, 1-fluoro-3-nitrobenzene exists as a liquid.

Melting point (Celsius)
-2.00
Melting point (Kelvin)
271.15
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
157.10g/mol
Molar mass
157.1120g/mol
Density
1.3720g/cm3
Appearence

1-Fluoro-3-nitrobenzene is a pale yellow liquid.

Comment on solubility

Solubility of 1-fluoro-3-nitro-benzene

1-fluoro-3-nitro-benzene, with its unique combination of functional groups, exhibits interesting solubility characteristics that are worth exploring. Here are some key points regarding its solubility:

  • Polarity: The presence of both a fluoro group and a nitro group contributes to the overall polarity of the molecule. This typically leads to enhanced solubility in polar solvents.
  • SOLVENT INTERACTIONS: 1-fluoro-3-nitro-benzene tends to dissolve well in solvents such as ethanol and acetone, which can accommodate polar interactions.
  • Limited Solubility: Conversely, its solubility in nonpolar solvents (like hexane) is generally low, as the polarity of the molecule diverges from the properties of nonpolar solvents.
  • Hydrophobic Effects: The bulky nature of the benzene ring, combined with its functional groups, may also impart some hydrophobic characteristics, impacting solubility in aqueous solutions.

In conclusion, 1-fluoro-3-nitro-benzene is moderately soluble in polar solvents, while showing poor solubility in nonpolar solvents, creating a fascinating balance driven by its molecular structure.

Interesting facts

Interesting Facts about 1-Fluoro-3-nitro-benzene

1-Fluoro-3-nitro-benzene is a fascinating compound that showcases the intricacies of aromatic chemistry. Here are some intriguing aspects to consider:

  • Dual Functional Groups: This compound features both a fluoro group and a nitro group attached to a benzene ring, which can significantly influence its reactivity. The presence of these substituents makes it a subject of interest in various chemical reactions.
  • Applications in Synthesis: 1-Fluoro-3-nitro-benzene acts as a useful intermediate in organic synthesis. Its chemical properties allow it to participate in substitution reactions, particularly in the synthesis of more complex fluorinated compounds.
  • Environmental Impact: Compounds containing both fluorine and nitro groups are often evaluated for their environmental implications. They can potentially serve as pollutants or bioactive compounds, which raises important questions in environmental chemistry.
  • Studies and Research: Ongoing research explores the role of such nitrofluorobenzenes in various biological systems. As a potential candidate for drug design, they may exhibit interesting pharmacological activities.
  • Enhanced Polarity: The combination of the electronegative fluorine atom and the strong electron-withdrawing nitro group results in an increased polarity, affecting its interaction with other molecules and solvents.

In summary, 1-fluoro-3-nitro-benzene represents a blend of unique structural characteristics and potential applications that make it a valuable compound for chemists exploring both synthetic and environmental realms. As researchers continue to investigate the behavior of such compounds, they may reveal more about their roles in chemical processes and their significance in various fields.

Synonyms
1-FLUORO-3-NITROBENZENE
402-67-5
3-Fluoronitrobenzene
m-Fluoronitrobenzene
Benzene, 1-fluoro-3-nitro-
m-Nitrofluorobenzene
1-Fluoro-3-nitro-benzene
CCK4NSJ7M3
3-nitrofluorobenzene
EINECS 206-953-0
MFCD00007196
NSC 60651
NSC-60651
1-NITRO-3-FLUOROBENZENE
DTXSID20193201
3-fluoro-1-nitrobenzene
1-fluoro-3-nitro benzene
NSC60651
3-fluoro-nitrobenzene
3-nitro-fluorobenzene
3-fluoro nitro benzene
2-fluoro-4-nitrobenzene
Nitrobenzene, 3-fluoro-
UNII-CCK4NSJ7M3
SCHEMBL248013
META FLUORO NITROBENZENE
CHEMBL164634
1-Fluoro-3-nitrobenzene, 97%
DTXCID90115692
BCP16131
Benzene, 1-fluoro-3-nitro-(8CI)
AKOS000120876
AKOS040744780
AC-2900
CS-W018306
AS-33375
Benzene, 1-fluoro-3-nitro-(8CI)(9CI)
DB-024003
F0110
NS00042783
EN300-20820
A25214
1-Fluoro-3-nitrobenzene, purum, >=97.0% (GC)
Q63395619
3-FluoronitrobenzenE;3-Fluoro-1-nitrobenzene;M-Nitrofluorobenzene
206-953-0