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4,4'-Difluorobiphenyl

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Identification
Molecular formula
C12H8F2
CAS number
398-23-2
IUPAC name
1-fluoro-4-(4-fluorophenyl)benzene
State
State

At room temperature, 4,4'-Difluorobiphenyl is in a solid state. It is stable under normal conditions of use and storage.

Melting point (Celsius)
81.00
Melting point (Kelvin)
354.15
Boiling point (Celsius)
271.00
Boiling point (Kelvin)
544.15
General information
Molecular weight
190.18g/mol
Molar mass
190.1820g/mol
Density
1.2040g/cm3
Appearence

4,4'-Difluorobiphenyl appears as a crystalline solid that is typically colorless to pale yellow. It may come also in powder form, depending on the polymorphic form and purity.

Comment on solubility

Solubility of 1-fluoro-4-(4-fluorophenyl)benzene

The solubility of 1-fluoro-4-(4-fluorophenyl)benzene, with the chemical formula C12H10F2, provides insight into its behavior in different solvents. Generally, this compound is categorized as a non-polar aromatic hydrocarbon due to its structure, which consists of a benzene ring with fluoro substituents. This affects its solubility properties in the following ways:

  • Solvent Compatibility: 1-fluoro-4-(4-fluorophenyl)benzene is expected to be more soluble in non-polar solvents such as hexane or toluene.
  • Low Polarity: Given its non-polar characteristics, it exhibits limited solubility in polar solvents like water or ethanol.
  • Fluorine Influence: The presence of fluorine atoms can slightly increase the compound's interactions with other solvents, but they do not significantly enhance solubility in polar environments.

As a rule of thumb, "like dissolves like" is a helpful principle here. Thus, one can anticipate that 1-fluoro-4-(4-fluorophenyl)benzene will demonstrate greater solubility in organic solvents compared to aqueous solutions. This understanding is crucial for applications in organic synthesis and industrial processes where solvent selection can impact reaction efficiency.

Interesting facts

Interesting Facts about 1-Fluoro-4-(4-fluorophenyl)benzene

1-Fluoro-4-(4-fluorophenyl)benzene is a fascinating compound with unique properties that makes it of interest in various fields of chemistry and industry.

Notable Features

  • Fluorinated Aromatic Compound: This compound belongs to the family of fluorinated aromatic hydrocarbons, which are known for their stability and distinctive reactivity due to the presence of fluorine atoms.
  • Application in Pharmaceuticals: Compounds like 1-fluoro-4-(4-fluorophenyl)benzene serve as building blocks in the synthesis of pharmaceuticals, benefiting from their ability to modify biological activity.
  • Material Science: The fluorine substituents lend this compound properties that can enhance the chemical resilience and thermal stability of materials, which is valuable in the manufacturing of polymers and advanced materials.

Research Perspectives

From a scientific angle, understanding the behavior of fluorinated compounds is essential as they often exhibit:

  • Reduced Reactivity: The electronegativity of fluorine can stabilize the molecular structure, leading to compounds with lower reactivity compared to their non-fluorinated analogs.
  • Unique Electronic Properties: The introduction of fluorine can significantly alter the electronic distribution in a molecule, impacting its optical and electronic behavior.

Environmental Considerations

As with many fluorinated compounds, environmental impact is an aspect that requires close attention:

  • Research is ongoing to evaluate the persistence of fluorinated compounds in the environment, with emphasis on their potential effects on ecosystems.
  • Regulatory measures are increasingly considering the use and development of fluorinated compounds to mitigate environmental and health risks.

In summary, 1-fluoro-4-(4-fluorophenyl)benzene is not just another compound; it embodies a rich interplay of chemistry, applications, and environmental stewardship, making it a notable subject of study and interest in the scientific community.

Synonyms
4,4'-Difluorobiphenyl
398-23-2
4,4'-Difluoro-1,1'-biphenyl
4,4'-Difluorodiphenyl
1-fluoro-4-(4-fluorophenyl)benzene
4,4-Difluoro-1,1-biphenyl
1,1'-Biphenyl, 4,4'-difluoro-
Biphenyl, 4,4'-difluoro-
P,P'-DIFLUOROBIPHENYL
O0694GMK81
NSC 4173
NSC-4173
EINECS 206-910-6
AI3-19148
DTXSID20192870
4,4'-DIFLUORODIPHENYL [MI]
MFCD00000349
4,4'-Difluorobiphenyl 2000 microg/mL in Acetone
4,4''-Difluorobiphenyl
UNII-O0694GMK81
NSC4173
Biphenyl, 4,4'-difluoro- (6CI,7CI,8CI); 4,4'-Difluoro-1,1'-biphenyl; 4,4'-Difluorobiphenyl; 4,4'-Difluorodiphenyl; NSC 4173; p,p'-Difluorobiphenyl
4,4'Difluorodiphenyl
Biphenyl,4'-difluoro-
4,4'-difluoro-biphenyl
4,4/'-Difluorobiphenyl
4,4\'-Difluorobiphenyl
Biphenyl, 4,4'difluoro
1, 4,4'-difluoro-
4,4'Difluoro1,1'biphenyl
SCHEMBL197346
1,1'Biphenyl, 4,4'difluoro
4,4'-Difluorobiphenyl, 97%
PZDAAZQDQJGXSW-UHFFFAOYSA-
DTXCID60115361
Biphenyl, 4,4'difluoro (8CI)
Biphenyl, 4,4'-difluoro-(8CI)
CS-M2784
4,4'-Difluoro-1,1'-biphenyl #
STL453629
1-fluoro-4-(4-fluorophenyl)-benzene
AKOS005255096
PS-8377
1,1'Biphenyl, 4,4'difluoro (9CI)
1,1'-Biphenyl, 4,4'-difluoro-(9CI)
D2181
NS00043139
Q27285154
InChI=1/C12H8F2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8H
206-910-6