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p-Fluorotoluene

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Identification
Molecular formula
C7H7F
CAS number
352-32-9
IUPAC name
1-fluoro-4-methyl-benzene
State
State

At room temperature, p-Fluorotoluene is a liquid. It is stable under normal conditions of use and storage, though it should be kept away from strong oxidizing agents.

Melting point (Celsius)
-32.40
Melting point (Kelvin)
240.75
Boiling point (Celsius)
129.70
Boiling point (Kelvin)
402.85
General information
Molecular weight
110.13g/mol
Molar mass
110.1270g/mol
Density
0.9987g/cm3
Appearence

p-Fluorotoluene is a clear colorless liquid that possesses an aromatic odor similar to benzene, with a slight sweetness due to the methyl group. It is often used in organic synthesis and chemical research.

Comment on solubility

Solubility of 1-fluoro-4-methyl-benzene

1-fluoro-4-methyl-benzene, also known as p-fluorotoluene, exhibits notable solubility characteristics that are important for its applications in organic chemistry.

In terms of solubility, consider the following:

  • Solvent Interaction: This compound is primarily soluble in organic solvents, such as ethanol and diethyl ether, reflecting its non-polar aromatic structure.
  • Temperature Dependence: The solubility of 1-fluoro-4-methyl-benzene may increase with raise in temperature, a common behavior for many organic compounds.
  • Limited Water Solubility: Due to its hydrophobic characteristics, this compound exhibits very low solubility in water, which can be typical for many fluorinated aromatic compounds.
  • Influence of Functional Groups: The presence of the fluorine atom provides unique properties that can alter its solubility compared to other methyl-substituted benzenes.

These solubility traits make 1-fluoro-4-methyl-benzene suitable for various synthetic applications, emphasizing the importance of understanding solubility in the context of chemical behavior.

Interesting facts

Interesting Facts about 1-Fluoro-4-methyl-benzene

1-Fluoro-4-methyl-benzene, also known as p-fluorotoluene, is an intriguing aromatic compound that presents unique properties and potential applications. Here are some fascinating aspects of this compound:

  • Aromatic Stability: This compound features a benzene ring, which is known for its stability due to resonance. The substitution of a fluorine atom and a methyl group enhances its chemical behavior, leading to interesting reactivity.
  • Fluorine's Influence: The presence of the fluorine atom in 1-fluoro-4-methyl-benzene contributes to its polarity and lipophilicity. Fluorine is known for its electronegative nature, often influencing the compound’s reactivity and interactions with other molecules.
  • Applications in Synthesis: It serves as a valuable intermediate in organic synthesis. The ability to introduce functionalities to aromatic compounds makes it a great candidate in the development of pharmaceuticals and agrochemicals.
  • Environmental Considerations: Understanding the behavior of 1-fluoro-4-methyl-benzene in different environmental conditions is important. Its persistence and potential impact suggest that further studies are essential in terms of toxicity and environmental fate.
  • Research Gateway: Scientists are continually exploring the compound's properties. It has been a subject of interest in studies focusing on the influence of fluorinated compounds on biological systems and catalysis.

In conclusion, 1-fluoro-4-methyl-benzene is not just a simple substitution of a benzene ring; it represents a gateway to advanced chemical studies, showcasing the interplay of structure and reactivity in organic chemistry. As stated by prominent chemists, "Every molecule tells a story," and this particular one opens up a wealth of possibilities.

Synonyms
4-Fluorotoluene
P-FLUOROTOLUENE
352-32-9
1-Fluoro-4-methylbenzene
Benzene, 1-fluoro-4-methyl-
p-Fluoromethylbenzene
Toluene, p-fluoro-
1-Methyl-4-fluorobenzene
p-Fluoromethyl benzene
p-tolyl fluoride
NSC 8861
NUD6WZ1B8F
para-Fluorotoluene
1-Fluoro-4-methyl-benzene
EINECS 206-520-6
BRN 1362373
AI3-28561
NSC-8861
FLUOROTOLUENE, P-
UN2388
P-FLUOROTOLUENE [MI]
CHEMBL346605
DTXSID7059852
4-05-00-00800 (Beilstein Handbook Reference)
UN-2388
2194-09-4
UNII-NUD6WZ1B8F
MFCD00000358
4-Fluorobenzyl radical
4-Fluorotoluene-?-d1
4-Fluorotoluene, 97%
WLN: FR D
SCHEMBL12689
(4-Fluorophenyl)methyl radical
SCHEMBL7257251
DTXCID6038958
4-FLUORO-1-METHYLBENZENE
NSC8861
GFA08890
BDBM50008544
STL280319
AKOS009031486
BP-12816
BS-23827
DB-023922
F0041
NS00041670
EN300-19368
p-Fluorotoluene [UN2388] [Flammable liquid]
Q26840772
F0001-1019
Z104473648
206-520-6