Skip to main content

4-Fluorobiphenyl

ADVERTISEMENT
Identification
Molecular formula
C12H9F
CAS number
324-60-3
IUPAC name
1-fluoro-4-phenyl-benzene
State
State

4-Fluorobiphenyl is typically found in a solid state at room temperature.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.15
General information
Molecular weight
172.20g/mol
Molar mass
172.1960g/mol
Density
1.1000g/cm3
Appearence

4-Fluorobiphenyl is a colorless crystalline solid.

Comment on solubility

Solubility of 1-Fluoro-4-phenyl-benzene

1-Fluoro-4-phenyl-benzene, with its chemical structure that includes a fluorine atom attached to a phenyl group, presents some intriguing solubility characteristics. Given its structure, we can anticipate certain trends:

  • Solvent Compatibility: This compound is generally more soluble in organic solvents due to its hydrophobic nature. Common solvents include:
    • Hexane
    • Toluene
    • Chloroform
  • Water Solubility: 1-Fluoro-4-phenyl-benzene has limited solubility in water. The presence of the fluorine atom does not significantly enhance its polarity, which results in its inability to interact favorably with water molecules.
  • Temperature Influence: Increasing the temperature can enhance its solubility in organic solvents as the kinetic energy of the molecules increases.

In summary, while 1-fluoro-4-phenyl-benzene is not water-soluble, its solubility in organic solvents makes it a potential candidate for various chemical applications, particularly in organic synthesis and material science. As a general rule, remember that the compound's solubility can be predicted by its structural features and the nature of the solvent.

Interesting facts

Interesting Facts About 1-Fluoro-4-phenyl-benzene

1-Fluoro-4-phenyl-benzene, often regarded in the realm of organic chemistry, is an intriguing compound with several notable aspects:

  • Reactivity: The presence of the fluorine atom in its structure influences its reactivity, making it a useful intermediate in the synthesis of various aromatic compounds.
  • Applications: This compound is particularly significant in the production of pharmaceuticals and agrochemicals, where it plays a role in enhancing biological activity.
  • Fluorinated Compounds: Compounds containing fluorine are known for their unique properties, including increased lipophilicity and thermal stability, which can affect the behavior of molecules in biological systems.
  • Research Interest: 1-Fluoro-4-phenyl-benzene has garnered attention in scientific studies focused on understanding reaction mechanisms and the effects of fluorination on molecular properties.

As a derivative of benzene with substituted phenyl and fluorine groups, this compound exemplifies the complexities involved in organic synthesis and molecular interactions. It serves as a fascinating study subject for chemists aiming to explore aromatic compounds' reaction pathways and applications in advanced materials and pharmaceuticals.

“The study of fluorinated derivatives opens a new world of possibilities in chemical synthesis, where subtle changes can lead to significant effects.”

Synonyms
4-FLUOROBIPHENYL
324-74-3
4-Fluoro-1,1'-biphenyl
p-Fluorodiphenyl
1-fluoro-4-phenylbenzene
4-Fluoro-1,1-biphenyl
Biphenyl, 4-fluoro-
4-Fluoro-1,1'-diphenyl
1,1'-Biphenyl, 4-fluoro-
para-Fluorobiphenyl
p-Fluorobiphenyl
(4-Fluorophenyl)benzene
4-Fluoro-biphenyl
EINECS 206-304-1
NSC 56686
MFCD00011650
DTXSID00186111
1-FLUORO-4-PHENYL-BENZENE
pFluorodiphenyl
4-Flurobiphenyl
paraFluorobiphenyl
4'-Fluorobiphenyl
Biphenyl, 4fluoro
4'-Fluoro-biphenyl
4Fluoro1,1'biphenyl
(4Fluorophenyl)benzene
1,1'Biphenyl, 4fluoro
4-Fluorobiphenyl, 95%
SCHEMBL412237
4-Fluoro-1,1'-biphenyl #
CHEMBL122439
DTXCID10108602
1,1'Biphenyl, 4fluoro (9CI)
NSC56686
1,1'-Biphenyl, 4-fluoro-(9CI)
NSC-56686
AKOS006223689
AB01065
FS-4454
AC-18713
SY049810
F0482
NS00041532
206-304-1