Skip to main content

1-Fluoro-6-isothiocyanatohexane

ADVERTISEMENT
Identification
Molecular formula
C7H12FNS
CAS number
1565-89-1
IUPAC name
1-fluoro-6-isothiocyanato-hexane
State
State

At room temperature, 1-Fluoro-6-isothiocyanatohexane is in a liquid state.

Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.15
Boiling point (Celsius)
180.30
Boiling point (Kelvin)
453.45
General information
Molecular weight
163.25g/mol
Molar mass
163.2460g/mol
Density
0.9875g/cm3
Appearence

1-Fluoro-6-isothiocyanatohexane typically appears as a clear, colorless liquid. It may have a faint odor characteristic of isothiocyanates.

Comment on solubility

Solubility of 1-fluoro-6-isothiocyanato-hexane

The solubility of 1-fluoro-6-isothiocyanato-hexane, a compound featuring both a fluorine atom and an isothiocyanate functional group, can be rather fascinating. Generally, the solubility of organic compounds can be influenced by several factors, including polarity, molecular size, and the presence of functional groups.

Key points regarding the solubility of this compound include:

  • Polarity: The presence of the electronegative fluorine atom tends to increase the polarity of the molecule, potentially enhancing its solubility in polar solvents such as water.
  • Functional Group Effects: The isothiocyanate group is known to both interact favorably with polar solvents and impart unique solubility characteristics, often enabling the compound to dissolve in a range of solvents.
  • Molecular Size: Given that 1-fluoro-6-isothiocyanato-hexane is a hexane derivative, its relatively larger carbon chain may limit solubility in highly polar solvents while providing better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or acetone.

In conclusion, while 1-fluoro-6-isothiocyanato-hexane exhibits some degree of solubility in various solvents, its specific solubility profile is likely influenced by the balance of its polar and non-polar characteristics. This balance makes it a compound of interest for further exploration in solubility studies.

Interesting facts

Interesting Facts about 1-Fluoro-6-isothiocyanato-hexane

1-Fluoro-6-isothiocyanato-hexane is a fascinating compound that belongs to the family of organic compounds known as isothiocyanates. These compounds are recognized for their diverse biological activities, and 1-fluoro-6-isothiocyanato-hexane is no exception. Here are some intriguing highlights about this compound:

  • Reactivity: The presence of both a fluorine atom and an isothiocyanate group contributes to the compound's unique reactivity profile.
    This makes it interesting for use in various chemical syntheses and modifications.
  • Biological Potential: Isothiocyanates are known for their potential antitumor properties. 1-Fluoro-6-isothiocyanato-hexane may present similar beneficial effects, making it a candidate for further study in pharmaceuticals.
  • Environmental Applications: Compounds like 1-fluoro-6-isothiocyanato-hexane can also play roles in agrochemicals, acting as natural pesticides. Their efficient mode of action provides an eco-friendly alternative to traditional chemical pesticides.
  • Fluorine Chemistry: The incorporation of fluorine into organic compounds generally enhances their stability and lipophilicity. This characteristic can lead to improved performance in various applications, particularly in drug formulation and design.
  • Structure-Activity Relationship (SAR): Understanding how the structure of 1-fluoro-6-isothiocyanato-hexane affects its biological activity can provide insights into rational drug design, where small changes can lead to more effective pharmaceuticals.

The unique combination of fluorine and isothiocyanate functionalities cements 1-fluoro-6-isothiocyanato-hexane as an exciting subject of study within the fields of synthetic organic chemistry and medicinal applications. As research progresses, this compound may lead to valuable contributions in various scientific domains.

Synonyms
6-Fluorohexyl isothiocyanate
334-52-1
ISOTHIOCYANIC ACID, 6-FLUOROHEXYL ESTER
BRN 1758830
DTXSID30187035
4-04-00-00719 (Beilstein Handbook Reference)
DTXCID40109526