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Cetylpyridinium chloride

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Identification
Molecular formula
C21H38ClN
CAS number
123-03-5
IUPAC name
1-hexadecylpyridin-1-ium;chloride
State
State

At room temperature, cetylpyridinium chloride is generally found in solid state as a powder or can be dissolved in water to form a solution.

Melting point (Celsius)
77.00
Melting point (Kelvin)
350.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
340.00g/mol
Molar mass
339.9960g/mol
Density
0.6000g/cm3
Appearence

Cetylpyridinium chloride is typically found as a white or almost white microcrystalline powder or granules. It is also available as a solution where it appears as a colorless to slightly yellow liquid.

Comment on solubility

Solubility of 1-hexadecylpyridin-1-ium chloride

The solubility of 1-hexadecylpyridin-1-ium chloride is an intriguing subject due to its amphiphilic nature, which results from the long hydrophobic alkyl chain attached to the pyridinium cation.

Key Points on Solubility:

  • Solvent Dependency: This compound demonstrates variable solubility depending on the solvent. It is generally soluble in polar solvents such as water, due to the ionic nature of the chloride, while it displays lower solubility in non-polar solvents.
  • Hydrophobic and Hydrophilic Balance: The long hydrocarbon tail enhances interactions with non-polar substances, yet the pyridinium moiety promotes interaction with polar solvents, suggesting dual solubility characteristics.
  • Temperature Effects: Solubility can be influenced by temperature; typically, increased temperature enhances solubility in most solvents.
  • Concentration Factors: At higher concentrations, 1-hexadecylpyridin-1-ium chloride may exhibit self-assembly behavior, forming micelles which can affect its overall solubility behavior in a given medium.

In summary, the solubility of 1-hexadecylpyridin-1-ium chloride is a balance of its hydrophilic and hydrophobic characteristics, which makes it suitable for various applications, especially in surfactant technologies and colloidal systems.

Interesting facts

Interesting Facts about 1-Hexadecylpyridin-1-ium Chloride

1-Hexadecylpyridin-1-ium chloride is a fascinating quaternary ammonium compound, known for both its unique properties and varied applications in the field of chemistry. Here are some noteworthy points about this versatile compound:

  • Pyridinium Ion: The compound contains a pyridinium ion, which is a positively charged nitrogen atom within a six-membered aromatic ring. This structure is fundamental to its biological activity.
  • Long-Chain Alkyl Group: The hexadecyl chain provides hydrophobic characteristics that contribute to its efficacy as a surfactant, enhancing its ability to interact with other organic materials.
  • Microbial Activity: Studies have shown that compounds like 1-hexadecylpyridin-1-ium chloride exhibit antimicrobial properties, making them useful in antiseptic applications.
  • Surface Activity: Due to its surfactant properties, it can reduce surface tension, which is beneficial in a variety of industrial formulations, including detergents and emulsions.
  • Versatile Solubility: The balance between its hydrophilic pyridinium part and hydrophobic hexadecyl chain grants this compound versatility in solubility, making it applicable in both aqueous and organic phases.
  • Biocompatibility: Research indicates that modifications to the alkyl chain length can affect cytotoxicity and enhance biocompatibility, which is essential for its use in medical applications.

In summary, 1-hexadecylpyridin-1-ium chloride is a compound that bridges the gap between organic chemistry and practical applications. Its unique molecular structure contributes to its functionality, ranging from antimicrobial agents to surfactants in various products. As research progresses, we may continue to uncover new roles for this intriguing chemical species.

Synonyms
cetylpyridinium chloride
123-03-5
hexadecylpyridinium chloride
Pristacin
Cepacol
Ceprim
Cetamium
Dobendan
Pyrisept
Aktivex
Biosept
1-Cetylpyridinium chloride
Ceepryn chloride
Cepacol chloride
Quaternario CPC
Acetoquat CPC
Intexsan CPC
Swabettes Hoechst
Ammonyx CPC
Medilave
Cetyl pyridinium chloride
Merocet
N-Hexadecylpyridinium chloride
N-Cetylpyridinium chloride
Ceeprin chloride
Cetylpyridini chloridum
Fixanol C
1-Palmitylpyridinium chloride
Cetylpyridinii chloridum
CETYLPYRIDINIUM CHLORIDE ANHYDROUS
Cloruro de cetilpiridinio
Chlorure de cetylpyridinium
Cetilpiridinio cloruro
6BR7T22E2S
DTXSID6041761
CHEBI:32915
NSC-14864
DTXCID4021761
Ceepryn
Pyridinium, 1-hexadecyl-, chloride (1:1)
NSC-756673
mouthwash
Antispetic
Catamium
Merovit
Corinz
Health
Search
BreathAway
CleanZing
mouth fresh
Scope
TheraStom
BioShell
Merocets plus
Alcohol Free
QCare
CVS Antiseptic
Gppe oral liq
Scope Icy Blast
E-zen Gargle
Gppe dental rinse
Chloride, Ceepryn
Antiplaque solution
Hello empower mint
Mint Alcohol Free
Suction Toothbrushes
Zestymint Antiseptic
Cepacol Antibacterial
cetylpyridium chloride
Crest Scope Original
Equate Healthy Mouth
SARINA
Mastikis fresh gargle
Oral B Gum Detoxify
Antiseptic Oral Rinse
Kalaya Breath Refresh
Cetylpyridinium cloride
Cetylpridinium Chloride
Oral B Plaque Defense
Oral-B Anti-Bacterial
Alcohol Free Antiseptic
Multi-Action Antiseptic
RefChem:5661
Hello Peace Out Plaque
cetylpyridinium chloratum
Killfire mouth freshener
SARINA ANTISEPTIC
Antigingivitis/Antiplaque
cAtylpyridinium (cation)
LAMRING COOL MINT
LAMRING STRAWBERRY
TheraBreath Healthy Gums
Breath mellow Water Lily
Chloride, Cetylpyridinium
Double X CONCENTRATED
Crest Pro-Health Clinical
Therabreath Plaque Control
PerCara Oral Health Rinse
QUALITY CHOICE MINT
Breath mellow Azalea Peach
Crest Pro-Health Advantage
Crest Pro-Health Gum Care
CloSYS Silver Healthy Gums
DuoCare Clinical Oral Rinse
Crest Pro-Health Germ Guard
Family Wellness Total Health
ReddyPort Antiplaque Solution
CETYLPRYIDINIUM CHLORIDE
COOL SENSE STICK GARGLE
Assured Oral Health Fresh Mint
Aurora Alcohol Free Clean Mint
CPH Anti-bacterial Breath Mist
Crest Pro-Health Bacteria Guard
Equaline Multi-Action Antiseptic
B05CA01
D08AJ03
D09AA07
HYVEE PRO CLEAN BLUE MINT
R02AA06
Roccos Old School Peircing Armor
Shopko Alcohol Free Multi Action
Crest Deep Cleanse Germ Treatment
Crest Pro-Health Multi-Protection
Kimvent Oral Care Toothbrush pack
Parodontax Active Gum Health Mint
TARGET UP AND UP GUM CARE
Therabreath Deep Clean Fresh Mint
BreathAway Mouth Rinse Fresh Mint
Anhydrous, Cetylpyridinium Chloride
Chloride Anhydrous, Cetylpyridinium
antigingivitis/antiplaque mouth rinse
CPC 1000 Pre and Post Teat Dip
Suction Swab with Corinz Oral Rinse
TheraBreath Healthy Gums Oral Rinse
Crest Pro-Health Intense Clean Mint
Crest Pro-Health Intense Fresh Mint
Denti Whoo Bubble Concentrated Gargle
PerCara Oral Health Rinse Fresh Mint
CETYLPYRIDINIUM CHLORIDE 0.05%
CPC 0.05% Antiplaque/Anti-gingivitis
Crest Pro-Health Gum and Breath Purify
Oral B Gum Detoxify Special Care Rinse
Parodontax Active Gum Health Clear Mint
DISCOUNT DRUG MART MINT MOUTHWASH
Colgate Total Active Prevention Spearmint
Crest Pro Health Gum plus Bacteria Guard
SmartMouth Mouthwash Clinical DDS Formula
Suction Toothbrush with Corinz Oral Rinse
Colgate Total Active Prevention Gum Health
Colgate Total Active Prevention Peppermint
SmartMouth Clinical Gum and Plaque Formula
Colgate Total Advanced Gum Health Mouthwash
Crest Pro-Health Breath Purify and Gum Care
SmartMouth Advance Clinical DDS Formula Mint
Oral B Plaque Defense Special Care Oral Rinse
Colgate Total 12 Hr Pro-Shield Spearmint Surge
Colgate Total Advanced Pro-Shield Peppermint Blast
Colgate Total Advanced Pro-Shield Spearmint Surge
Equate Healthy Gums Clean Mint Breath Oral Rinse
QCARE ORAL CLEANSING AND SUCTIONING SYSTEM
Crest Pro-Health Pro Active Defense Whole Mouth Clean
QCare Petite Size Oral Cleansing and Suctioning System
Scope All Day CPC Antigingivitis/Antiplaque Mouthwash
Crest Pro-Health Multi-Protection Refreshing Clean Mint
Hello Peace Out Plaque peace out, plaque antigingivitis
Scope Get Fresh CPC Antigingivitis/Antiplaque Mouthwash
SmartMouth SmartMouth Gum Health Zinc Activated Formula
Parodontax Active Gum Health Daily Mouthwash Breath Freshener
Scope All Day CPC Antigingivitis/Antiplaque Mouthwash All Day
Toothette Oral Care Single Use System with Antiseptic Oral Rinse
204-593-9
QCare Oral Cleansing and Suctioning System compatible with 0.12% Chlorhexidine Gluconate (CHG) Oral Rinse
D9OM4SK49P
NB-002
1-hexadecylpyridin-1-ium chloride
1-Hexadecylpyridinium chloride
Tserigel
Pyridinium, 1-hexadecyl-, chloride
Cetylpyridinium chloride [INN]
MFCD00011731
Cetylpyridinium (chloride)
1-Hexadecylpyridin-1-ium;chloride
Caswell No. 166A
HSDB 38
Cetilpiridinio cloruro [DCIT]
EINECS 204-593-9
Cetylpyridinii chloridum [INN-Latin]
NSC 14864
EPA Pesticide Chemical Code 069160
UNII-6BR7T22E2S
Cloruro de cetilpiridinio [INN-Spanish]
Chlorure de cetylpyridinium [INN-French]
AI3-15070
NB 002
1-Hexadecylpyridinium chloride (1:1)
Cetyl-pyridinium chloride
hexadecylpyridine, chloride
SCHEMBL4763
CHEMBL34833
SPECTRUM1500169
orb1300767
1-Hexadecyl-Pyridinium Chloride
1-hexadecylpyridin-1-iumchloride
HMS501B08
HY-B1464R
HMS1920M13
HMS2091A20
HMS3652F05
HMS5082L04
Pharmakon1600-01500169
HY-B1464
NSC14864
Tox21_301296
CCG-39719
CETYLPYRIDINIUM CHLORIDE [MI]
MSK163017
NSC756673
s4172
SBB080799
AKOS005267197
Cetylpyridinium (chloride) (Standard)
CETYLPYRIDINIUM CHLORIDE [HSDB]
KS-5309
WLN: T6KJ A16 & Q & G
CETYLPYRIDINIUM CHLORIDE [WHO-DD]
NCGC00094618-01
NCGC00094618-02
NCGC00257543-01
AC-32490
CAS-123-03-5
DB-041704
A5161
CS-0013168
H0078
NS00093500
SW222237-1
EN300-23845
F20369
A832584
Q418318
SR-05000001582
SR-05000001582-1
Z89264780