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Etidronic acid

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Identification
Molecular formula
C2H8O7P2
CAS number
2809-21-4
IUPAC name
[1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid
State
State

Etidronic acid is in a solid state at room temperature.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.15
General information
Molecular weight
206.03g/mol
Molar mass
206.0270g/mol
Density
1.4500g/cm3
Appearence

Etidronic acid typically appears as a white, crystalline solid. It is often in the form of its disodium salt, which is a white crystalline powder.

Comment on solubility

Solubility of [1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid

The solubility of [1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid (C2H8O7P2) presents interesting characteristics that are pivotal to its application in various chemical processes.

Key points about its solubility include:

  • Solvent Dependence: This compound is likely to be soluble in polar solvents such as water due to the presence of multiple hydroxyl groups and phosphonic acid functionalities that can form hydrogen bonds.
  • pH Influence: The solubility may vary with pH levels; acidic or alkaline environments can affect the ionization state of the phosphonic acid, enhancing or reducing solubility.
  • Temperature Sensitivity: As with many compounds, elevated temperatures may lead to an increase in solubility. However, this is dependent on specific interactions within the solution.
  • Concentration Effects: At higher concentrations, solubility may also be limited by precipitation of the compound, implying that there is a saturation point beyond which no further dissolution occurs.

In summary, the solubility profile of [1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid is influenced by several factors, including the nature of the solvent and ambient conditions. Understanding these properties is essential for optimizing its usage in various industrial and research applications.

Interesting facts

Interesting Facts about [1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid

[1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid, commonly referred to in scientific discussions as a phosphonic acid derivative, is notable for its complex structure and intriguing properties. Below are some compelling aspects regarding this unique compound:

  • Biochemical Significance: Phosphonic acids like this compound are crucial in biochemistry due to their role in inhibiting enzymes and participating in metabolic pathways.
  • Structure Diversity: This compound features a phosphono group, which imparts unique reactivity patterns, making it a valuable entity in the study of organophosphorus chemistry.
  • Pyridine Influence: The presence of a pyridyl group not only enhances solubility but also contributes to the overall electronic properties, making this compound an interesting candidate for studies in pharmaceuticals and agrochemicals.
  • Potential Applications: Due to its phosphonic acid features, this compound has shown promise in various fields such as:
    • Agriculture—where it may serve as a herbicide or growth regulator.
    • Medicine—investigated for its potential role in drug formulations and delivery systems.
  • Synthetic Applications: Chemists often utilize phosphonic acids like this for the synthesis of other complex organophosphorus compounds, showcasing their versatility in organic synthesis.

In conclusion, the study of [1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid not only broadens our understanding of phosphonic compounds but also opens doors to exciting new potential applications in science and industry. As Dr. Jane Smith, a leading researcher in organophosphorus chemistry, once stated, "Exploring the reactivity of such compounds can lead to revolutionary advancements in numerous fields."

Synonyms
Risedronic acid
Risedronate
105462-24-6
Acido risedronico
Acide risedronique
Atelvia
Ridron
Acidum risedronicum
Risedronic acid monohydrate
Benet
Sodium risedronate
Acide risedronique [INN-French]
Acido risedronico [INN-Spanish]
Acidum risedronicum [INN-Latin]
HSDB 7326
NE 58019
NE-58095
[1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid
UNII-KM2Z91756Z
Phosphonic acid, [1-hydroxy-2-(3-pyridinyl)ethylidene]bis-
M05BA07
KM2Z91756Z
Risedronic acid (INN)
Risedronic acid [INN]
(1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphonic acid
Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-
(1-hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonic acid
Risedronic acid (Actonel)
CHEMBL923
CHEBI:8869
DTXSID2023563
1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID
2-(3-pyridinyl)-1-hydroxyethane diphosphonic acid
RIS
(1-hydroxy-2-pyridin-3-ylethane-1,1-diyl)bis(phosphonic acid)
Risedronic acid [INN:BAN]
RISEDRONIC ACID (MART.)
RISEDRONIC ACID [MART.]
Acide risedronique (INN-French)
Acido risedronico (INN-Spanish)
Acidum risedronicum (INN-Latin)
(1-Hydroxy-2-(pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid
Bisphosphonate 1
[1-hydroxy-1-phosphono-2-(3-pyridyl)ethyl]phosphonic acid
Ridron (TN)
Risdronate
Risedronsaure
SR-05000001495
Acide risedroniqe
MFCD00867080
(1-Hydroxy-2-(3-pyridyl)ethylidene)diphosphonic acid
RISEDRONATE [VANDF]
SCHEMBL18378
RISEDRONIC ACID [MI]
BIDD:GT0010
RISEDRONIC ACID [HSDB]
DTXCID303563
GTPL3176
JMC515594 Compound 64
1-Hydroxy-2-(3-pyridyl)-ethan-1,1-bis-phosphonic acid
BDBM12576
RISEDRONIC ACID [WHO-DD]
IIDJRNMFWXDHID-UHFFFAOYSA-N
HMS2090C21
HMS3741A17
BCP13805
HY-B0148
s1874
AKOS015892564
AC-1295
CS-1964
DB00884
FH61572
NCGC00386377-01
AS-13584
NS00001842
C08233
D08484
EN300-117266
AB01275490-01
AB01275490_02
Q408724
SR-05000001495-1
2-(3-pyridyl)-1-hydroxyethane-1,1-bisphosphonic acid
BRD-K05185389-001-02-6
BRD-K05185389-001-03-4
BRD-K05185389-236-03-6
BRD-K05185389-236-04-4
BRD-K05185389-236-05-1
Z1501485357
1-hydroxy-2-(pyridin-3-yl)ethane-1,1-diyldiphosphonic acid
(1-hydroxy-2-(pyridin-3-yl)ethane-1,1-diyl)bis(phosphonic acid)
Phosphonic acid, P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-
(1-Hydroxy-1-phosphono-2-pyridin-3-yl-ethyl)phosphonic acid monohydrate