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carphedon

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Identification
Molecular formula
C16H21NO2
CAS number
77472-70-9
IUPAC name
1-hydroxy-1,1-diphenyl-4-(1-piperidyl)butan-2-one
State
State

At room temperature, carphedon is in a solid state. It is typically handled as a powder or in crystal form for pharmaceutical applications.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
445.30
Boiling point (Kelvin)
718.45
General information
Molecular weight
275.35g/mol
Molar mass
275.3450g/mol
Density
1.1050g/cm3
Appearence

Carphedon typically appears as a white crystalline powder. The crystalline nature gives it a shiny appearance when viewed in bulk.

Comment on solubility

Solubility of 1-hydroxy-1,1-diphenyl-4-(1-piperidyl)butan-2-one

The solubility of 1-hydroxy-1,1-diphenyl-4-(1-piperidyl)butan-2-one in various solvents exhibits some interesting characteristics. This compound, which features both hydrophobic phenyl groups and a hydrophilic piperidyl moiety, allows for a balance between solubility in organic and aqueous environments.

Factors Influencing Solubility:

  • Polarity: The presence of the hydroxyl group (–OH) contributes to greater polarity, often enhancing solubility in polar solvents such as water.
  • Hydrophobic Interactions: The diphenyl and butanone structures may hinder solubility in highly polar solvents, leading to preferential solubility in organic solvents like ethanol or dichloromethane.
  • Temperature: Increased temperature can generally enhance solubility by increasing molecular motion and interactions, although this can vary depending on the solvent.

Therefore, one might observe that:
- In polar solvents, this compound may show moderate solubility due to hydrogen bonding capabilities.
- In nonpolar solvents, solubility may be higher due to favorable van der Waals interactions with the large phenyl groups.

In conclusion, understanding the solubility profile of 1-hydroxy-1,1-diphenyl-4-(1-piperidyl)butan-2-one can greatly aid in its application in chemical processes and allow for optimization in various formulations.

Interesting facts

Interesting Facts about 1-Hydroxy-1,1-diphenyl-4-(1-piperidyl)butan-2-one

This fascinating compound is a member of the family of ketones, exhibiting unique chemical and physical properties that make it a subject of interest in various fields including medicinal chemistry and organic synthesis. Below are some intriguing highlights:

  • Structural Diversity: The presence of both phenyl groups and a piperidine ring in the structure contributes to its diverse reactivity and interaction with biological systems.
  • Biological Relevance: Compounds similar to this one have been explored for their potential therapeutic effects, particularly in neuropharmacology, due to their interaction with neurotransmitter systems.
  • Synthesis and Applications: Researchers are constantly looking into efficient synthetic routes for preparing this compound, making it a valuable target for organic synthesis. It can be a building block for complex organic molecules.
  • Pharmacophore Analysis: The distinct structural features of the piperidyl and diphenyl moieties allow for interesting studies concerning their roles in the binding affinity and selectivity of potential drug candidates.

In the words of chemists, "Understanding the intricacies of such compounds opens pathways to innovative solutions in drug development and material science." Each aspect of 1-hydroxy-1,1-diphenyl-4-(1-piperidyl)butan-2-one not only highlights its chemical significance but also underscores its role as a potential key player in advancing therapeutic strategies.

Synonyms
2-BUTANONE, 1,1-DIPHENYL-1-HYDROXY-4-PIPERIDINO-
24860-77-3
1,1-Diphenyl-1-hydroxy-4-piperidino-2-butanone
BRN 1351466
DTXSID60179569
5-20-02-00414 (Beilstein Handbook Reference)
RefChem:257782
DTXCID70102060
2-Butanone,1,1-diphenyl-1-hydroxy-4-piperidino-