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Hydroxymethylphenylurea

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Identification
Molecular formula
C9H10N2O2
CAS number
83-16-3
IUPAC name
1-hydroxy-3-methyl-1-phenyl-urea
State
State

The compound is a crystalline solid at room temperature.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
165.19g/mol
Molar mass
165.1890g/mol
Density
1.2490g/cm3
Appearence

Hydroxymethylphenylurea typically appears as a white to off-white crystalline solid. The compound is solid at room temperature and exhibits a crystalline structure.

Comment on solubility

Solubility of 1-hydroxy-3-methyl-1-phenyl-urea

The solubility of 1-hydroxy-3-methyl-1-phenyl-urea (C10H12N2O) presents some interesting characteristics. This compound, which features both hydrophilic and hydrophobic elements, tends to exhibit the following solubility behavior:

  • Water Solubility: It has moderate solubility in water due to the presence of the hydroxyl group, which is conducive to hydrogen bonding with water molecules.
  • Solvents: 1-hydroxy-3-methyl-1-phenyl-urea is soluble in organic solvents such as ethanol and acetone, reflecting its non-polar phenyl group.
  • Temperature Influence: As with many organic compounds, solubility can increase with temperature, making it advisable to conduct solubility assessments at varied temperatures for better results.

In summary, while the solubility of 1-hydroxy-3-methyl-1-phenyl-urea allows for a wide range of applications in both polar and non-polar environments, researchers must carefully consider the conditions under which the compound is utilized. Its dual nature of being both aqueous and solvent-soluble opens pathways for versatile applications in the chemical and pharmaceutical industries.

Interesting facts

Interesting Facts About 1-Hydroxy-3-Methyl-1-Phenyl-Urea

1-Hydroxy-3-methyl-1-phenyl-urea is a fascinating compound that has garnered attention in various scientific fields due to its unique properties and applications. Here are some engaging insights:

Key Highlights

  • Structure and Synthesis: This compound exhibits a urea framework, which is integral to many biological molecules. The presence of both a hydroxyl group and a phenyl group enhances its versatility in chemical reactions.
  • Biological Relevance: Urea derivatives have been widely studied for their potential biological activities. They can serve as intermediates in the synthesis of pharmaceuticals, making them noteworthy in medicinal chemistry.
  • Analytical Applications: The ability of 1-hydroxy-3-methyl-1-phenyl-urea to form stable complexes with various metal ions can be exploited in analytical chemistry for the development of sensor technologies.
  • Research Potential: This compound is often used in research for studying mechanisms of drug action, toxicity, and in the design of new chemical entities with improved properties.

Incorporating urea derivatives like 1-hydroxy-3-methyl-1-phenyl-urea in pharmaceutical formulations can enhance efficacy and reduce side effects. As stated by notable chemists, "The journey of a chemical compound is often filled with unexpected discoveries." There remains much to explore regarding this compound's reactivity and capabilities, making it an exciting subject for ongoing research.

Overall, 1-hydroxy-3-methyl-1-phenyl-urea exemplifies the intersection of organic chemistry and medicinal applications, showcasing the nuanced roles that small molecular changes can have on a compound's functionality.

Synonyms
METURIN
N-Hydroxy-N'-methyl-N-phenylurea
N-Phenyl-N-hydroxy-N'-methylurea
Urea, 1-hydroxy-3-methyl-1-phenyl-
BRN 1074038
DTXSID80211672
0-15-00-00009 (Beilstein Handbook Reference)
DTXCID10134163
1-hydroxy-3-methyl-1-phenylurea
6263-38-3
Urea, N-hydroxy-N'-methyl-N-phenyl-
Cambridge id 5130358
SCHEMBL11036446
1-Methyl-3-phenyl-3-hydroxyurea
HLXRWUNSSVKCJL-UHFFFAOYSA-N
HMS1674E17
N-phenyl-N-hydroxy-N' -methylurea
STK396582
AKOS000546172