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Berbamine

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Identification
Molecular formula
C37H40N2O6
CAS number
478-61-5
IUPAC name
1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one
State
State

At room temperature, Berbamine is typically found in a solid state.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.00
Boiling point (Celsius)
430.00
Boiling point (Kelvin)
703.00
General information
Molecular weight
379.47g/mol
Molar mass
379.4700g/mol
Density
1.3980g/cm3
Appearence

The compound typically appears as a yellow powder or crystalline material. It is not characterized by any distinctive odor.

Comment on solubility

Solubility of 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one

The solubility of 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one (C37H40N2O6) is an intriguing phenomenon that can be influenced by various factors. As a complex organic molecule, its solubility is likely governed by several key properties:

  • Polarity: The presence of hydroxymethyl and methoxy groups suggests some degree of polarity, which might improve solubility in polar solvents.
  • Hydrogen Bonding: The hydroxymethyl function can participate in hydrogen bonding, potentially enhancing solubility in protic solvents such as water and alcohols.
  • Hydrophobic Regions: The hydrocarbon portion of the molecule may leverage solubility in nonpolar solvents, indicating a dual solubility profile.

Common observations about the solubility of similar compounds can also be noted. For example, compounds with hydroxyl or methoxy groups often exhibit:

  1. A higher solubility in organic solvents compared to purely hydrophobic compounds.
  2. A tendency to form stable solutions or colloids when mixed with surfactants or certain polymeric additives.

Ultimately, the solubility of 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one may vary widely, and experimental data would provide the most reliable information. Exploring the interaction with solvents and assessing solubility through various conditions is essential for understanding its chemical behavior.

Interesting facts

Interesting Facts about 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one

1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one is a fascinating compound that resides within the broader category of isoquinolines, a group of alkaloids that exhibit diverse biological activities. Here are some intriguing insights into this compound:

  • Biological Significance: Isoquinolines are renowned for their various pharmacological properties. Compounds in this family often demonstrate antioxidant, antimicrobial, and antitumor activities, making them subjects of interest in medicinal chemistry.
  • Molecular Structure: The unique structure of 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one highlights the presence of a hydroxymethyl group, which enhances its reactivity and potential interactions with biological macromolecules. This functionality may play a crucial role in its therapeutic properties.
  • Natural Sources: Many isoquinoline derivatives are found in plants, contributing to plant defense mechanisms and showcasing the interconnectedness of nature's chemistry. Researchers continue to explore how these compounds can be harnessed for beneficial applications in pharmaceuticals.
  • Synthesis and Research: The synthesis of such compounds is of great interest in organic chemistry. Researchers develop new synthetic pathways not only to produce these compounds but also to modify their structures, thus optimizing their biological activities.
  • Future Potential: Given the ongoing research into isoquinolines, there is potential for developing novel therapeutic agents based on this compound. Studies may reveal more about how 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one can be utilized in treating various diseases.

In conclusion, 1-(hydroxymethyl)-7-methoxy-2H-isoquinolin-6-one exemplifies the rich diversity of the isoquinoline family and accentuates the intricate relationship between chemical structure and biological activity. As the field of medicinal chemistry evolves, the possibilities for this compound remain exciting and ripe for exploration.