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Phenylephrine Hydrochloride

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Identification
Molecular formula
C9H14NO2Cl
CAS number
61-76-7
IUPAC name
1-[hydroxy(phenyl)methyl]propylammonium;chloride
State
State

At room temperature, Phenylephrine hydrochloride is in a solid state. It maintains its crystalline structure under standard conditions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
203.67g/mol
Molar mass
203.6730g/mol
Density
1.1750g/cm3
Appearence

Phenylephrine hydrochloride appears as a white or almost white crystalline powder. It is hygroscopic in nature, meaning it can absorb moisture from the air. The compound is odorless.

Comment on solubility

Solubility of 1-[hydroxy(phenyl)methyl]propylammonium chloride

The solubility of 1-[hydroxy(phenyl)methyl]propylammonium chloride can be intriguing due to its unique structure. This compound contains an ammonium group, which typically enhances solubility in polar solvents. Here’s a closer look at its solubility characteristics:

  • Polar Solvents: Compounds with ammonium groups are generally soluble in polar solvents such as water. The ability to form hydrogen bonds with water enhances solubility.
  • Low Solubility in Organic Solvents: In non-polar or less polar organic solvents, the solubility is expected to be quite limited. This is due to the compound's ionic character.
  • pH Dependency: The solubility may also depend on the pH of the solution. In acidic conditions, protonation of the amine group can lead to increased solubility.

In conclusion, while 1-[hydroxy(phenyl)methyl]propylammonium chloride is likely to be soluble in water due to its ammonium group, its solubility profile can change based on various environmental factors. Always consider these aspects when preparing or using this compound in various applications.

Interesting facts

Interesting Facts about 1-[hydroxy(phenyl)methyl]propylammonium;chloride

This compound is a fascinating representative of the class of ammonium salts, and it has sparked interest for its potential applications in various fields of chemistry and pharmaceuticals. Here are some intriguing aspects:

  • Biological Relevance: Compounds of this type often exhibit biological activity, which makes them valuable in medicinal chemistry. Their ability to interact with biological systems opens up possibilities for drug design and development.
  • Ionization Properties: The presence of the ammonium ion makes this compound a good candidate for studying ionic interactions in solution. This property can be critical for understanding solubility, reactivity, and overall behavior in biological contexts.
  • Functional Groups: The hydroxy and phenyl groups in the structure contribute to its ability to engage in hydrogen bonding and π-π stacking interactions. This can influence both the stability and reactivity of the compound, as well as its interactions with other molecules.
  • Applications in Material Science: Compounds like 1-[hydroxy(phenyl)methyl]propylammonium;chloride are investigated for their potential use as polymer additives or surfactants, as the ammonium and hydroxy groups may enhance material properties.
  • Synthesis and Characterization: The synthesis of such compounds can be achieved through various methods, providing a rich area for experimental investigation and characterization through techniques such as NMR and mass spectrometry.

As chemists, we often find that the interaction of various functional groups within a molecule can lead to unexpected properties. Understanding these interactions is key to harnessing the potential of compounds like 1-[hydroxy(phenyl)methyl]propylammonium;chloride in research and industry.

In essence, this compound serves as a reminder of the intricate relationships between molecular structure and functionality, inspiring countless research avenues in the pursuit of new technologies and therapeutic agents.

Synonyms
Nor-homoephedrine
Phenylbutanolamine hydrochloride
alpha-(alpha-Aminopropyl)benzyl alcohol hydrochloride
NSC 24527
BENZYL ALCOHOL, alpha-(1-AMINOPROPYL)-, HYDROCHLORIDE, (+-)-
Benzenemethanol, alpha-(1-aminopropyl)-, hydrochloride
(1-hydroxy-1-phenylbutan-2-yl)azanium;chloride