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1-Hydroxypiperidine

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Identification
Molecular formula
C5H11NO
CAS number
6800-18-2
IUPAC name
1-hydroxypiperidine
State
State

1-Hydroxypiperidine is a liquid at room temperature.

Melting point (Celsius)
25.00
Melting point (Kelvin)
298.15
Boiling point (Celsius)
216.00
Boiling point (Kelvin)
489.15
General information
Molecular weight
101.15g/mol
Molar mass
101.1530g/mol
Density
0.9950g/cm3
Appearence

1-Hydroxypiperidine is a colorless to pale yellow liquid. It is typically used in organic synthesis and can become more colorful when impurities are present.

Comment on solubility

Solubility of 1-hydroxypiperidine

1-hydroxypiperidine, with the chemical formula C5H11NO, displays notable solubility characteristics that are interesting to explore. This compound is a derivative of piperidine and features a hydroxyl group, which significantly influences its solubility properties.

Some key points about the solubility of 1-hydroxypiperidine include:

  • Polarity: The presence of the hydroxyl group (-OH) increases the polarity of the molecule, enhancing its capacity to form hydrogen bonds with water.
  • Water Solubility: 1-hydroxypiperidine is generally considered soluble in water, which is typical for many compounds containing hydroxyl groups.
  • Organic Solvents: This compound is also soluble in various organic solvents such as methanol and ethanol, making it versatile in various chemical reactions.
  • Temperature Effect: As the temperature increases, solubility in water typically increases as well, which is an important consideration in laboratory settings.

In summary, 1-hydroxypiperidine exhibits good solubility in both polar and non-polar solvents, largely due to its structural features that facilitate interactions such as hydrogen bonding. Understanding these solubility characteristics is crucial for its applications in research and industry.

Interesting facts

Interesting Facts About 1-Hydroxypiperidine

1-Hydroxypiperidine is a fascinating chemical compound, belonging to the piperidine family. This compound has garnered interest in various fields, including medicinal chemistry and organic synthesis, due to its unique properties and potential applications. Here are some captivating aspects of 1-hydroxypiperidine:

  • Chemical Structure: The structure of 1-hydroxypiperidine features a six-membered ring containing nitrogen, which is part of the piperidine structure. The presence of a hydroxyl group (-OH) adds to its reactivity and makes it a versatile building block in organic synthesis.
  • Biological Importance: 1-hydroxypiperidine has been studied for its potential pharmaceutical applications. Compounds with similar structures have been implicated in various biological activities, leading to research in drug development and agrochemicals.
  • Synthesis: The synthesis of 1-hydroxypiperidine can be accomplished through various methods, including the reduction of specific precursors or reactions involving piperidine derivatives. This flexibility makes it an appealing target for chemists interested in synthetic methodology.
  • Solubility: One notable feature of 1-hydroxypiperidine is its ability to interact with both hydrophilic and hydrophobic environments, making it suitable for diverse applications in chemical reactions and formulations.
  • Research Applications: Due to its functional hydroxyl group, this compound can serve as a precursor for synthesizing more complex molecules, enabling researchers to create new materials with tailored properties.

In conclusion, 1-hydroxypiperidine presents a compelling study subject for scientists and students alike. Its distinctive features and potential applications make it a noteworthy compound in the world of chemistry.

Synonyms
Piperidin-1-ol
1-Hydroxypiperidine
N-Hydroxypiperidine
1-PIPERIDINOL
Piperidine, 1-hydroxy-
EINECS 225-362-9
BRN 0102726
DTXSID9063611
LKPFBGKZCCBZDK-UHFFFAOYSA-
5-20-03-00478 (Beilstein Handbook Reference)
1Piperidinol
Piperidin1ol
1Hydroxypiperidine
Piperidine, 1hydroxy
DTXCID7040603
225-362-9
inchi=1/c5h11no/c7-6-4-2-1-3-5-6/h7h,1-5h2
lkpfbgkzccbzdk-uhfffaoysa-n
4801-58-5
MFCD00038048
9ANQ5DB3A2
Piperidinol
hydroxypiperidine
piperidol
N-hydroxy-piperidine
1-hydroxy-piperidine
UNII-9ANQ5DB3A2
SCHEMBL1360
CHEMBL277887
STK331484
AKOS015897997
CS-W016646
1-Hydroxypiperidine, >=96.0% (GC)
AS-38272
DA-18313
SY240047
NS00031750
EN300-6472910
Q6951371